Ireland
--:--IST
Latest
Clinical Trials in Israel / NCT05766592
Recruiting Phase 3

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

NCT05766592 · tracked via the Priya Life Science Israel tracker
Phase
Phase 3
Started
2024-08-13
Last updated
2026-01-13

Condition(s) studied

Mental Health IssueParent-Child Relations

Investigational drug(s) / intervention(s)

LGBTQ-affirmative CBTABFT-SGM

LGBTQ-affirmative CBT: 16-session LGBTQ-affirmative psychotherapy using cognitive behavioral techniques

ABFT-SGM: 16-session attachment-based family therapy for sexual and gender minority young adults and their nonaccepting parents

Study summary

The purpose of this study is to assess the efficacy of an LGBTQ-affirmative individual cognitive behavioral psychotherapy (CBT) and LGBTQ-affirmative family therapy (attachment-based family therapy for sexual and gender minority young adults; ABFT-SGM) delivered via telehealth to a sample of sexual and gender minority adults with nonaccepting parent(s) in New York, Pennsylvania, Connecticut, and Israel. The investigators will assess whether both treatments are associated with significant decreases in depressive and anxiety symptoms. The investigators will also assess whether and how each treatment achieves reductions in mental health symptoms through specific mechanisms (e.g., rejection sensitivity, internalized stigma, emotion dysregulation, parental rejection and acceptance).

Eligibility

Sex
ALL
Min age
20 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * be 20 and older * be fluent in English * self-identify as lesbian, bisexual, queer, pansexual, or other non-heterosexual identity * currently experience elevated depressive or anxiety symptoms (screened initially using a cutoff of ≥ 2.5 on the Brief Symptom Inventory-4 and further confirmed by the BDI and BAI). * report at least moderate levels of parental rejection or low levels of parental acceptance, as measured using the PARSOS. * have at least one rejecting/nonaccepting parent that agrees to participate in the therapy. * live in New York State, Pennsylvania, Connecticut, or Israel. Exclusion Criteria: * report current mental health treatment ≥1 day/month (except for medication management ≤1 day/week) * report beginning a new medication within the past 30 days * exhibit active psychosis or active mania, as assessed by the SCID-Psych Screen. * exhibit active suicidality or active homicidality, as assessed by the SIDAS * be currently legally mandated to attend treatment * demonstrate gross cognitive impairment, as assessed with the Telephone Interview for Cognitive Status * do not have a parent willing to participate

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
Yale LGBTQ Mental Health Initiative with the Yale School of Public Health Office New York New York Not Yet Recruiting
Ben-Gurion University Psychotherapy Research Lab Beersheba Israel Recruiting

More Yale University trials in Israel

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05766592 on ClinicalTrials.gov ↗ ← All trials in Israel