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Clinical Trials in Israel / NCT00353210
Recruiting Observational

The Derivation of Human Embryonic Stem Cell Lines From PGD Embryos

NCT00353210 · tracked via the Priya Life Science Israel tracker
Phase
Observational
Started
2004-04-06
Last updated
2025-03-05

Condition(s) studied

Infertility

Study summary

Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body. hESC are important for studying developmental biology and for cell replacement therapies for the treatment of degenerative human diseases. An additional use for embryonic stem cells would be for the in vitro study of diseases. hESC lines derived from embryos diagnosed as abnormal by PGD testing would afford such models for study. Because embryos tested by PGD and found to be abnormal would only under rare circumstances be transferred to the uterus of a woman (and in most cases would be discarded), the derivation of new hESC lines from these embryos would provide a viable less ethically-objectionable source of cells with which to study the mechanisms of differentiation and developmental biology.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Couple has derived embryos by IVF. * Couple has tested these embryos by PGD and does not want to utilize the embryos to build their families. * Couple signs informed consent. Exclusion Criteria: * Couple does not sign informed consent.

Trial sites (1)

FacilityCityRegionStatus
Hadassah Medical Organization Jerusalem Israel Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT00353210 on ClinicalTrials.gov ↗ ← All trials in Israel