Haptic stimulation device: Both patients and healthy participants will perform manual dexterity tasks using the Dextrain Manipulandum. In addition, they will receive finger vibrations delivered via rings that we have previously developed. These vibrations will have a frequency of 150 Hz and will be delivered for a duration of 150 ms.
Brain MRI: Subjects and patients will undergo anatomical, resting-state functional, and diffusion brain MRI sequences.
Study summary
In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation. We will also evaluate the integrity of brain structure and function using MRI.
Eligibility
Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* First symptomatic stroke, ischaemic or haemorrhagic in the early subacute phase (up to 3 weeks post-stroke)
* Upper limb paresis (≤4/5 MRC Scale)
* Ability to grasp, lift and put down 1 block (from the BBT test)
* Be affiliated to a social security
Exclusion Criteria:
* Presence of another neurological or musculoskeletal condition affecting upper limb movement
* Severe cognitive impairment and/or aphasia with inability to understand and carry out instructions
* Contraindications to MRI (claustrophobia, presence of cochlear implants and/or pacemakers)
* Persons subject to legal protection measures
* Persons subject to judicial protection measures
* Pregnancy
* Life-threatening conditions or conditions requiring follow-up at 6 months
* Epilepsy
* Known hypersensitivity or allergy to silicone
Primary outcome measure(s)
Gain in the prediction of manual dexterity recovery — 3 months post enrollment The primary outcome measure is a 10% improvement in the prediction of the Box and Block Test (BBT) score at 3 and 6 months post-stroke achieved by adding the haptic effect to a multivariate model.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
