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Clinical Trials in France / NCT07337889
Recruiting Not applicable

Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder

NCT07337889 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2026-06-01
Last updated
2026-06-22

Condition(s) studied

Borderline Personality DisorderBorderline Personality Disorder (BPD)Bipolar Disorder (BD)

Investigational drug(s) / intervention(s)

Relationship-use questionnaire

Relationship-use questionnaire: Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships

Study summary

This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability.

The study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships.

This innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a "Relationship Use Disorder."

Eligibility

Sex
ALL
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria: * General : aged 18-45 * Specific : * Borderline personality disorder (BPD)assessed by SCID, without bipolar disorder * Bipolar disorder (assessed by SCID), without BPD (evaluated by SCID) * Healthy controls with no psychiatric disorders (screened by SCID). Exclusion Criteria: * Psychotic disorders (evaluated by SCID) * lack of informed consent * Not affiliated with social security * Under judicial or administrative confinement or involuntary hospitalization * Protected by law (e.g., under guardianship) * Pregnancy or breastfeeding * Inability to understand, speak, or write in French * Inability to understand the study's purpose or methodology * Excluded from another study during the exclusion period * Participants who have received over €6000 in annual indemnities * For Bipolar Participants (without BPD) : Current moderate or severe depressive episode (BDI score \> 18) or Current hypomanic/manic episode (YMRS \< 12)

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
CHU Montpellier Montpellier France Recruiting

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07337889 on ClinicalTrials.gov ↗ ← All trials in France