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Clinical Trials in France / NCT07036445
Recruiting Not applicable

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain

NCT07036445 · tracked via the Priya Life Science France tracker
Sponsor
Clinique du Sport, Bordeaux Mérignac
Phase
Not applicable
Started
2025-09-11
Last updated
2025-09-18

Condition(s) studied

Herniated Disc

Investigational drug(s) / intervention(s)

Epidural Steroid InjectionEpidural platelet-rich plasma injection

Epidural Steroid Injection: Intervention consists of interlaminar CT guided epidural steroid injection

Epidural platelet-rich plasma injection: Intervention consists of interlaminar CT guided epidural platelet-rich plasma injection after recovery of plasma by blood sampling and centrifugation

Study summary

The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications.

This study aims to compare these two treatments over the long term (2 years).

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Diagnosis of unilateral resistant LRP associated with a herniated disc on MRI images. (Diagnosis of resistance after 6 weeks of appropriate medical treatment). Exclusion Criteria: * Patients with infections, * Patients who have had previous percutaneous corticosteroid injections, * Patients undergoing systemic corticosteroid treatment, * Patients with immune deficiencies, * Patients who are allergic to the contrast medium used, * Pregnant or breastfeeding patients, * Patients with a history of allergies to anesthetics or corticosteroids, * Anticoagulant treatment or blood disorders, patients on antiplatelet therapy * Taking NSAIDs within two weeks prior to the procedure

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Clinique du Sport Mérignac France Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07036445 on ClinicalTrials.gov ↗ ← All trials in France