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Clinical Trials in France / NCT06865040
Recruiting Not applicable

Perioperative Inhaled Therapy in Carcinological Thoracic Surgery in Patients at High Risk of Postoperative Pulmonary Complications

NCT06865040 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire, Amiens
Phase
Not applicable
Started
2025-07-31
Last updated
2026-01-16

Condition(s) studied

Thoracic SurgeryPostoperative Pulmonary Complications (PPCs)

Investigational drug(s) / intervention(s)

Formoterol Fumarate 12 mcg (Foradil Aerolizer)Usual treatment

Formoterol Fumarate 12 mcg (Foradil Aerolizer): Administration in the interventional arm of long-acting inhaled ß-2 mimetics: FORMOTEROL FUMARATE 12 µg pwd inhalation capsule (FORMOTEROL VIATRIS®), taken twice a day intraoperatively from Day-2 to Day 7.

Usual treatment: usual treatment

Study summary

The objective of the study is to evaluate, in a clinical trial, the efficacy of peri operative administration of long-acting inhaled ß-2 mimetics on the occurrence of postoperative pulmonary complications

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adult (\>18 years) * Lung cancer eligible for surgical management by lung resection (non-small cell lung carcinoma = NSCLC) by any route * Naïve to long-term inhaled bronchodilator therapy * High risk of post-operative pulmonary complications (Pre-operative FEV1 \< 80%) Exclusion Criteria: * Patient refusal * Pregnancy * Emergency surgery * Patient with a physiological status of WHO IV or ASA ≥ IV * Asthma * Patients treated with long-acting bronchodilators * Severe heart failure (NYHA IV), unstable ischaemic heart disease (angina or recent infarction \< 3 months), obstructive hypertrophic cardiomyopathy, subvalvular aortic stenosis, severe uncontrolled hypertension Recent stroke \< 3 months * High-grade unresponsive conductive disorders or unstable arrhythmia * Thyrotoxicosis, pheochromocytoma * Unbalanced diabetes * Hypersensitivity to ß-2 mimetics or lactose * Current participation in a trial of another drug therapy

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
CHRU Amiens Amiens France Recruiting

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Other trials for the same condition

Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery Recruiting
Prediction of Postoperative Pulmonary Complications in Thoracic Surgery Starting soon
Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery Starting soon
Risk Factors of Atrial Fibrillation After Cardiac Surgery Starting soon
Diagnosis of Atrial Fibrillation in Postoperative Thoracic Surgery Using a Smartwatch Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06865040 on ClinicalTrials.gov ↗ ← All trials in France