Magnetoencephalography by Optical Pumping Magnetometer

NCT05835817 · tracked via the Priya Life Science France tracker

Sponsor

Centre Hospitalier Universitaire, Amiens

Phase

Not applicable

Started

2023-04-11

Last updated

2025-05-28

Condition(s) studied

MagnetoencephalographyOptical Pump MagnetometerNeonatePremature

Investigational drug(s) / intervention(s)

Magnetoencephalography

Magnetoencephalography: 40 minutes of Magnetoencephalography with Optical Pump Magnetometer

Study summary

MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling.

The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.

Eligibility

Sex

ALL

Min age

1 Day

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * For healthy adult volunteers * Age between 18 and 65 * No pathology, no treatment * No toxicant intake * For term newborns * Child between 38 and 42 weeks gestational age on the day of registration * No pathology, no treatment * For children born prematurely * Child between 28 and 36 weeks gestational age on the day of registration * No pathology, no treatment apart from routine care related to prematurity * For pregnant women * Pregnant with between 28 to 40 weeks gestational age on the day of registration * No pathology, no treatment Exclusion Criteria: * Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible. * Patients who cannot stand to stand still for a few minutes. * Newborn on ventilatory assistance or infusion * Newborn baby not meeting the age criteria

Primary outcome measure(s)

Signal to noise ratio of the MEG OPM — 1 day
Signal to noise ratio of the MEG OPM is in dB
Signal to noise ratio of HR EEG — 1 day
Signal to noise ratio of HR EEG is in dB
Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG — 1 day

Trial sites (1)

Facility	City	Region	Status
CHU Amiens	Amiens	France	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05835817 on ClinicalTrials.gov ↗ ← All trials in France