ENDOMETRIOSIS - MRI

NCT05779462 · tracked via the Priya Life Science France tracker

Sponsor

University Hospital, Lille

Phase

Observational

Started

2023-05-23

Last updated

2025-12-26

Condition(s) studied

EndometriosisMobility LimitationMagnetic Resonance ImagingDiagnosisPelvisComparative Study

Investigational drug(s) / intervention(s)

Dynamic MRI Sequence

Dynamic MRI Sequence: Addition of a Dynamic MRI Sequence during the MRI examination performed in routine care

Study summary

Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes clinical diagnosis difficult. It therefore seems important to improve the complementary examinations available to make the diagnosis more precise and to better study the effectiveness of the treatments implemented. The clinical examination and per-surgical findings of patients with deep pelvic endometriosis show a clear decrease in the mobility of the pelvic organs in relation to each other, but few studies have looked at this mobility, which could however have an implication in explaining the pathophysiology of the disease and the symptomatology of the patients, as well as in the detection of lesions preoperatively. The persistence of hypo-mobility could also help to understand treatment failures.

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

50 Years

Healthy volunteers

Inclusion Criteria: * Patient referred for suspected pelvic endometriosis requiring pelvic MRI * Female, nulliparous, * patient with signed written consent, patient with health insurance, * patient willing to comply with all study procedures and duration Exclusion Criteria: * BMI \> 35, * history of hereditary collagen and elastic tissue disease, * history of pelviperitonitis, * history of major pelvic surgery, * inability to receive informed information, * inability to participate in the entire study, * lack of social security coverage, * refusal to sign consent

Primary outcome measure(s)

the mean vertical displacement (in millimeters) measured on the anterior wall of the vagina between rest and maximum pushing force during dynamic MRI — Baseline

Trial sites (1)

Facility	City	Region	Status
Service de chirurgie gynécologique Hôpital Jeanne de Flandre - CHU de LILLE	Lille	France	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05779462 on ClinicalTrials.gov ↗ ← All trials in France