Intravenous lidocaine administration: General anesthesia with intravenous lidocaine administration
Study summary
The goal of this study is, in a population of patients undergoing ERCP surgery, treated preventively with NSAIDs and divided into two groups according to the absence (group 1) or presence (group 2) of intravenous lidocaine in the general anesthesia protocol.
The main objective of this study is to compare the incidence of post-ERCP pancreatitis between the two groups.
type of study: clinical trial participant population/health conditions: Patients with ERCP surgery
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patient over 18 years of age
* Patient who has read and signed the consent form for participation in the study
* Patient candidate for ERCP with virgin papilla
Exclusion Criteria:
* Patient with sphincterotomized papilla
* Patient under court protection, guardianship or curatorship
* Pregnant woman or woman of childbearing age without highly effective contraception for the duration of the study (surgically sterile, intrauterine device (\> 14 days), hormonal contraception (same dose and formulation for at least 6 months), sexual abstinence. Women after menarche and until they become postmenopausal, unless they are permanently infertile or have undergone surgical sterilization, are considered to be of childbearing age, i.e. fertile. A postmenopausal condition is defined as the absence of menstruation for 12 months without any other medical cause
* Patient not affiliated with the French social security system
* Patient participating in another clinical research protocol
* Impossibility to give the subject informed information and/or written informed consent: dementia, psychosis, disorders of consciousness, non-French speaking patient
* Contraindication to the use of NSAIDs
* Contraindication to anesthesia or to the administration of any of the products used in anesthesia protocols (including lidocaine)
Primary outcome measure(s)
Plasma lipase level — Hour 24 A plasma lipase level greater than or equal to 3N, considered to be indicative of a PAP, is the primary endpoint of the study
Trial sites (1)
Facility
City
Region
Status
Hôpital Privé des Peupliers
Paris
France
Recruiting
More GCS Ramsay Santé pour l'Enseignement et la Recherche trials in France
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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