Psychotic DisordersPsychosisSchizophrenia and Related DisordersSchizophrenia ProdromalDiagnosis, Psychiatric
Study summary
Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic transition to validate a french predictive model of this transition using computerized speech analysis techniques
Eligibility
Sex
ALL
Min age
15 Years
Max age
30 Years
Healthy volunteers
No
Inclusion Criteria:
* Major and/or minor from 15 to 30 years old
* Who alleged a suicidal gesture or idea or behavior that has repercussions in their emotional, social or professional life
* If patients receive neuroleptic treatment that impairs cognitive abilities, a one-week wash-out period will be scheduled prior to assessment.
* Affiliated with or beneficiary of a health insurance/social security system
* Able and willing to provide written informed consent
Exclusion Criteria:
* History of psychosis
* Risk of self-harm or violence not compatible with outpatient treatment
* QI\<70 (WAIS)
* Neurological disorder or major health problem
* Impossibility to interrupt neuroleptic treatment for one week
* Refusal to participate
Primary outcome measure(s)
Transition to schizophrenia — 2 years Determined from the CAARMS scale (COMPREHENSIVE ASSESSMENT OF AT RISK MENTAL STATES)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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