Sensori-motor and Perceptual Functions of the PPC.

Condition(s) studied

Investigational drug(s) / intervention(s)

point targets: In the experiences 1 and 2, the participant needs to point different visual targets (LED) in the dark.

tactile stimulation: In the experience 3, a tactile stimulation is applied to the middle finger of the 2 hands. The participant needs to indicate into a microphone when he feels the stimulation.

visual images: Target dots or visual images are presented on a computer screen. The participant is required to point to the targets or to react as soon as possible by pressing a response button when they are detected.

Study summary

To produce hand's movement directed towards a target, the investigator must combine several sensory information, such as vision or proprioception. The posterior parietal cortex (PPC) is a region of the cortex involved in this multisensory integration. A lesion of the PPC cause a visuo-motor trouble called optic ataxia but these patients also have perceptual troubles.

The aim of the study is to understand the different functions of the PPC and especially how the processes of spatial coding of the sensory information influences perception and motor planning.

In this study, the investigator want to explore the sensory motor and the perceptual performance of patients with optic ataxia compared with healthy subjects, using 6 behavioral tests.

Objectify the consequences of PPC impairment (visual-motor and perceptual consequences) on patients' quality of life and autonomy.

Eligibility

Primary outcome measure(s)

• response error - number of pointing error — Day 0 after each stimulation
• response error -measure of reaction times — Day 0 after each stimulation
• response error - percentage of right responses — Day 0 after each stimulation

Trial sites (1)

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