Clinical Trials in Egypt / NCT07112703
Recruiting Not applicable

Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major

NCT07112703 · tracked via the Priya Life Science Egypt tracker
Sponsor
Rawan Mohammed Khairy Mostafa Elsawy
Phase
Not applicable
Started
2025-04-07
Last updated
2025-08-08

Condition(s) studied

Incentive SpirometerPulmonary FunctionFunctional CapacityChild, OnlyThalassemia Major

Investigational drug(s) / intervention(s)

Incentive spirometer exercisesDiaphragmatic breathingPursed lip breathing:Costal breathing exercises

Incentive spirometer exercises: The study group was instructed to use an incentive spirometer, which should be held upright, sealed around the mouthpiece, and taken slowly and deep breaths. They will be motivated to achieve a preset volume through visual feedback. The child will hold their breath for 2-3 seconds at full inspiration and, after each set of 10 breaths, cough to clear mucus from the lungs. The exercise duration is 15 minutes.

Diaphragmatic breathing: The child will lie on their back, place one hand on their belly and one on their chest, and use a balloon or doll to fill both belly and chest up like a balloon. Inhale deeply, let the hands on the belly rise, then exhale slowly, making the belly down. The exercise will last for 10 minutes.

Pursed lip breathing:: Sit in a seated position with crossed legs or knees. Inhale slowly through the nose for three seconds, then exhale through pursed lips, similar to blowing out birthday candles.

Costal breathing exercises: The study involves conducting Costal breathing exercises for children. The exercises involve placing hands on the apical region of the lung, turning the child's head, relaxing the shoulder and neck muscles, taking a deep breath, pushing the hand out, holding, and exhaling slowly. The hands provide pressure and resistance after initiation of inspiration, and the children rest for 2 minutes between exercises. The duration of the exercise varies between the control and study groups.

Study summary

The study was done to:

1. Investigate the effect of respiratory training on functional lung capacity and
2. To detect the effect of respiratory training on pulmonary functions in children with β-thalassemia major.
3. To detect the level of oxygen saturation and heart rate during and after blood transfusion in children with β-thalassemia major.

Eligibility

Sex
ALL
Min age
6 Years
Max age
10 Years
Healthy volunteers
No
Inclusion Criteria: 1. Diagnosed as thalassemia \& subjected to blood transfusion 2. Their age range from 6 to 10 years old 3. Both sexes, male and female, will participate. 4. Subjects are able to follow simple verbal commands or instructions included in the procedures. Exclusion Criteria: 1. Children with mental retardation or any other disability . 2. Children with visual or hearing defects. 3. Children with cardiovascular, chest pulmonary, and heart diseases. 4. Children with any postoperative cardiovascular, chest pulmonary, and heart conditions.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Zagazig university hospitals. Zagazig Egypt Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07112703 on ClinicalTrials.gov ↗ ← All trials in Egypt