Protocol-driven Nutrition in Preterm Infants

Condition(s) studied

Investigational drug(s) / intervention(s)

Nutrition plan supported by advanced clinical nutrition software: Infants undergo regular anthropometric assessments (weight, length, head circumference), and detailed fluid and nutrient intake is recorded. Weekly analysis of the macronutrient composition of maternal or donor milk is conducted, enabling personalized fortification to meet the infant's current needs. The intervention utilizes a dedicated nutrition software tool, incorporating Fenton growth charts, to support clinical decisions and track progress via z-scores compared to term-born infants. By aligning nutrient supply with individual requirements and promoting early enteral feeding, the project seeks to enhance growth outcomes, minimize risks such as bronchopulmonary dysplasia or retinopathy, and shorten the length of stay in neonatal intensive care.

Study summary

The project is a national, prospective, multicenter, interventional pilot project focused on protocol-driven nutrition in preterm infants in the Czech republic.

The primary aim of the project is to prepare, test, and develop a proposal for a national methodology for the care of preterm newborns in the field of nutrition. This will reduce health risks in premature infants and minimize the negative impacts on the overall development of the child and the family of the premature infant.

Eligibility

Primary outcome measure(s)

• Z-score for body weight at 36 weeks corrected gestational age — Up to a corrected gestational age of 36 weeks
• Z-score for body length at 36 weeks corrected gestational age — Up to a corrected gestational age of 36 weeks
• Z-score for head circumference at 36 weeks corrected gestational age — Up to a corrected gestational age of 36 weeks

Trial sites (5)

More Institute of Health Information and Statistics of the Czech Republic trials in Czechia