Memory in Neurology project (PAMNEU) aims to map the distribution and severity of cognitive impairment in patients of outpatient neurologic offices across the geographical area of the Czech Republic. 1000 patients in 50 neurologic offices will undergo cognitive tests (ALBA and PICNIR) and psychometric scales (FAQ-CZ and GDS-CZ) to asses their functional state and depressive symptoms.
The trial's primary goal is to assess the distribution of cognitive impairment among diagnostic groups in neurologic care according to the ICD-10. Additionally, the feasibility of ALBA and PICNIR methods to uncover previously undiagnosed cognitive impairments will be evaluated.
Eligibility
Sex
ALL
Min age
50 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Dispensarization of at least six months in an outpatient neurologic office with an ICD-10 diagnosis
* Age\>=50
* Permanent residency in the geographical area of the Czech Republic
Exclusion Criteria:
* Diagnosis of mental retardation (F70-F79) according to ICD-10
* Refusal to sign the informed consent and consent with GDPR
* Uncorrected visual impairment
* Uncorrected auditory impairment
* Impairment of hand movement preventing the patient from filling in the questionnaires.
* Inability to participate in the project
Primary outcome measure(s)
Baseline ALBA — Established on Day 0 as a single assessment. Amnesia Light and Brief Assessment (ALBA) test is an innovative method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-12 (a lower value denotes a more severe cognitive impairment).
Baseline PICNIR — Established on Day 0 as a single assessment. Picture Naming and Immediate Recall test (PICNIR) is an innovative test method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-20 (a lower value denotes a more severe cognitive impairment).
Statistical analysis of ALBA results — The final statistical analysis will be performed through study completion, an average of 6 months. Statistical analysis of ALBA results compared to groups determined by ICD-10 diagnosis and demographical data.
Statistical analysis of PICNIR results — The final statistical analysis will be performed through study completion, an average of 6 months. Statistical analysis of PICNIR results compared to groups determined by ICD-10 diagnosis and demographical data.
Trial sites (1)
Facility
City
Region
Status
Teaching Hospital Královské Vinohrady
Prague
Prague
More Charles University, Czech Republic trials in Czechia
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
