Hypertrophic Scar Prosthetic Pressure in Burn Amputee

Condition(s) studied

Investigational drug(s) / intervention(s)

Skin assessment of prothesis interface and control area: Evaluation of Melamin and erythema (Mexameter), TEWL ( Tewameter), skin elasticity (Cutometer), skin thickness (Dermascan)

Interface pressure: Mean and peak interface pressure (limb to prosthetic)

Study summary

Amputation following burn injury is rare but complex, affecting predominantly younger individuals with extensive burns, particularly electrical injuries, and often resulting in residual limbs characterized by scarring, contractures, grafted or flapped tissues, and heightened vulnerability to skin breakdown. Prosthesis-covered burn scars often appear to heal better than uncovered areas, suggesting a potential therapeutic pressure effect; however, excessive localized peak pressures may also contribute to recurrent wounds in grafted or scarred tissues. This study aims to quantify prosthesis-induced pressures on the residual limbs of burn-injured amputees and evaluate the feasibility and reliability of applying pressure measurement tools validated in burn care to this distinct clinical context.

Eligibility

Primary outcome measure(s)

• Prosthetic-induced interface pressure — From enrollment to end of visit (2 hours)
  quantification of interface pressure (mmHg) at predefined residual limb sites in burn-related amputees, assessing within-subject differences in interface pressure

Trial sites (1)

More Centre hospitalier de l'Université de Montréal (CHUM) trials in Canada

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