Mindfulness practice with Tao Art (Calligraphy and Song Greatest Love)
Mindfulness practice with Tao Art (Calligraphy and Song Greatest Love): During mindfulness practice with Tao Art (Calligraphy and Greatest Love Song), participants will repeatedly trace the lines of calligraphy with fingers while listening to, singing, or chanting with Tao Song. This enables them to achieve deep concentration, while maintaining fully alert state. The practice can be done in sitting or standing, depending on the health status and age and will last 30 minutes and is done daily for 12 months.
Study summary
The goal of this pilot clinical trial is to learn if a subtle energy transmission and Tao Calligraphy Mindfulness Practice works to improve mitochondrial DNA. The main questions it aims to answer are:
* Does Tao Calligraphy Mindfulness practice improve mitochondrial DNA content in peripheral blood leucocytes in adults?
* Will this improvement of mitochondrial DNA content in peripheral blood leucocytes be statistically significant? Researchers will compare the values of mitochondrial DNA content in peripheral blood leucocytes at beginning of the mindfulness practices to the values at 3 months, 6 months and 12 months of practice group.
Participants will:
* have blood samples will drawn at accredited institutions and analyzed for Mitochondrial DNA content in Leucocytes upon entry into the study - Baseline time point; at 3-months time point, at six-months time point and at twelve-months time point.
* All participants will complete the set of 3 questionnaires upon entry into the study - Baseline time point; at 3-months time point, at six-months time point and at twelve-months time point.
* Practice the Mindfulness with Tao Calligraphy minimum 30 minutes daily.
Eligibility
Sex
ALL
Min age
19 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Age 19 and over
* Willingness and ability to comply with data collection requirements
* Submission of required documentation before entering the study, including informed consent and consent to release of information
* Healthy or Ill, with the exception of genetic illnesses and cancer (for which treatments could negatively impact measurement) and serious mental disorders (e.g. bipolar disorder, schizophrenia, psychosis),
* Willingness to allow their data to be used for research purposes and published as deemed fit (while conforming to all applicable privacy laws) by Sha Research Foundation.
* Willingness to practice the daily calligraphy meditations and follow the protocol.
Exclusion Criteria:
* Not meeting any of the inclusion criteria
* Bipolar disorders, other serious mental disorders (e.g. schizophrenia, psychosis), genetic illnesses (primarily affected chromosomes), and cancer (treatment could negatively impact telomere during research period)
* inability to sign consent and follow instructions
* Unwillingness to participate in data gathering
* Unable to follow the practice regimen, including the daily calligraphy meditations
* Pregnant or nursing. Participants who become pregnant during the study will be required to end their participation. (to avoid any, at current time unknown, potential negative effect of the study on the fetus).
* There are no exclusion criteria placed upon potential subjects related to national origin, culture, ethnicity, race, sex, physical disability, sexual orientation, religion, or spiritual practices.
Primary outcome measure(s)
Mean Change from Baseline in Mitochondrial-to-nuclear genome ratio (Mitochondrial DNA content) in peripheral blood Leukocytes at 3 months, 6 months and 12 months — From start of Mindfulness practices with Tao Art (Calligraphy and Song Greatest Love) to end of practices at 12 months Genomic DNA is extracted from peripheral blood and DNA concentration and purity are assessed by spectrophotometer. Mitochondrial DNA content in leukocytes is quantified by real-time quantitative PCR. Calculating Mitochondrial DNA content is done as follows: Ct values for Mitochondrial DNA targets are normalized to the nuclear gene Ct using the delta-delta cycle threshold method, using equation: Mitochondrial DNA content = relative Mitochondrial DNA abundance / nuclear DNA abundance. This ratio reflects the relative number of mitochondrial genomes per nuclear genome in leukocytes.
The normal range for the mitochondrial-to-nuclear genome ratio (Mitochondrial DNA/ Nuclear DNA) in human blood leukocytes is approximately 1.2 to 1.8.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
