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Clinical Trials in Brazil / NCT07466069
Recruiting Not applicable

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

NCT07466069 · tracked via the Priya Life Science Brazil tracker
Sponsor
University of Sao Paulo
Phase
Not applicable
Started
2026-03
Last updated
2026-03-12

Condition(s) studied

Obesity & OverweightEating DisordersBody Image DisturbanceGender Diverse Populations

Investigational drug(s) / intervention(s)

TransForm Health Program

TransForm Health Program: A 6-month structured intervention including monthly adolescent group sessions, monthly caregiver sessions, monthly individual goal-setting meetings, and weekly reinforcement messages focused on healthy eating, physical activity, body appreciation, and prevention of unhealthy weight-control behaviors.

Study summary

Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities. However, no structured lifestyle interventions specifically tailored to this population have been developed.

This randomized controlled trial aims to evaluate the effectiveness of a 6-month interdisciplinary lifestyle intervention designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14 years. Participants will be randomized (1:1) to either an intervention group receiving monthly group sessions (for adolescents and caregivers separately) and weekly supportive messages, or a control group receiving standard outpatient care and general health recommendations.

The primary outcome is quality of life measured by the WHOQOL-BREF. Secondary outcomes include eating disorder symptoms, body image, diet quality, physical activity levels, sedentary behavior, body composition, and anthropometric measures.

Eligibility

Sex
ALL
Min age
10 Years
Max age
14 Years
Healthy volunteers
No
Inclusion Criteria: * Aged 10-14 years * Self-identified as transgender or gender-diverse Exclusion Criteria: * Current diagnosis of eating disorder requiring specialized treatment * Severe psychiatric instability * Cognitive impairment limiting participation

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo São Paulo São Paulo Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07466069 on ClinicalTrials.gov ↗ ← All trials in Brazil