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Clinical Trials in Brazil / NCT06737614
Recruiting Observational

Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study

NCT06737614 · tracked via the Priya Life Science Brazil tracker
Sponsor
Pontificia Universidad Catolica de Chile
Phase
Observational
Started
2025-05-01
Last updated
2025-05-29

Condition(s) studied

Critical Illness

Study summary

The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients.

We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions.

Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * 18 years * Admitted to ICU * Functioning arterial line in place Exclusion Criteria: * Pregnancy * Inadequate arterial line transduction (see below) * Refusal of consent * Patient who requires extracorporeal circulation

Primary outcome measure(s)

Trial sites (3)

FacilityCityRegionStatus
Hospital Do Coracao São Paulo Brazil Recruiting
Hospital Clinico UC Christus Santiago Chile Recruiting
Fundacion Valle del Lili Cali Colombia Recruiting

Other trials for the same condition

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE) Recruiting
Patient Characterization Panel to Improve Satisfaction With the Intensive Care Unit Stay (CONNECT) Starting soon
Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU Recruiting
Swallowing Assessment for Predicting Extubation Failure in Critically Ill Patients Starting soon
Volume Removal Intolerance During Net Ultrafiltration in Acute Kidney Injury Patients Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06737614 on ClinicalTrials.gov ↗ ← All trials in Brazil