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Clinical Trials in Brazil / NCT06661356
Starting soon Not applicable

Peer-led Community-based PrEP Delivery Among Youth in Brazil

NCT06661356 · tracked via the Priya Life Science Brazil tracker
Sponsor
University of Alabama at Birmingham
Phase
Not applicable
Started
2026-10
Last updated
2026-03-05

Condition(s) studied

Pre-Exposure Prophylaxis (PrEP)HIV

Investigational drug(s) / intervention(s)

COMPrEP

COMPrEP: Participants will be paired with peer lay workers and will meet with peer lay workers at private community location. They will discuss options for oral PrEP with peer lay workers and be provided provide daily oral PrEP or event-driven (2-1-1) PrEP. Participants will take part in rapid HIV testing at each visit. They will also meet with peer lay workers at private community location for follow-up at 1, 5, 9, and 13 months.

Study summary

The goal of this project is to conduct a series of studies to refine, test, and understand experiences with a peer-led community-based intervention in which youth will be integrated into health care teams and trained to deliver HIV pre-exposure prophylaxis (PrEP) to their peers. The study team will conduct a randomized trial to determine if peer delivery of PrEP to youth aged 15-24 in Brazil will increase PrEP uptake, persistence, and adherence compared to standard PrEP care provided in health facilities.

Eligibility

Sex
ALL
Min age
15 Years
Max age
24 Years
Healthy volunteers
Accepted
Eligibility Criteria: * Aged 15-24 years * Candidate for HIV prevention * Sexually active * Not currently using PrEP * Willing to discuss oral PrEP * Agree to be randomized to either intervention or standard care arm Exclusion Criteria: * HIV positive test result * Not currently sexually active * Currently using PrEP

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
Federal University of Bahia Salvador Estado de Bahia
University of São Paulo São Paulo São Paulo

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06661356 on ClinicalTrials.gov ↗ ← All trials in Brazil