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Clinical Trials in Brazil / NCT03574103
Recruiting Not applicable

Chronic Effect of Fasting

NCT03574103 · tracked via the Priya Life Science Brazil tracker
Sponsor
Federal University of Minas Gerais
Phase
Not applicable
Started
2018-07-09
Last updated
2025-03-18

Condition(s) studied

Overweight and Obesity

Investigational drug(s) / intervention(s)

Caloric restriction onlyCaloric restriction plus TRF morningCaloric restriction plus TRF night

Caloric restriction only: Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements), without restriction in time for feeding, for 8 weeks.

Caloric restriction plus TRF morning: Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 12 p.m. to 8 p.m.) and 16 hours of fasting, for 8 weeks.

Caloric restriction plus TRF night: Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 8 a.m. to 4 p.m.) and 16 hours of fasting, for 8 weeks.

Study summary

The aim of the study is to determine if time-restricted feeding (TRF) is an effective dietary strategy to weight loss after 8 weeks intervention. TRF will be compared with an intervention without restriction in time for feeding. Both strategies will be with caloric restriction.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
59 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Females; * Aged between 18 and 59 years old; * Body mass index equal or greater 25 kg/m²; * Agree to sign the informed consent. Exclusion Criteria: * Any chronic health conditions (e.g. chronic renal failure, autoimmune, heart, and liver disease); * Thyroid diseases or medications for its treatment; * Medications known to affect total energy expenditure; * Use of steroids, immunosuppressants or non-steroidal anti-inflammatory drugs, weight-loss medications, oral hypoglycemic agents or insulin and any medications that influence metabolic and/or inflammatory parameters; * Previous surgery for weight loss; * Pregnancy or breast-feeding; * Smoking; * Alcohol use (\>2 doses/day).

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
Hospital da Clínicas Belo Horizonte Minas Gerais Recruiting
Hospital das Clínicas Belo Horizonte Minas Gerais Recruiting

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Other trials for the same condition

Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity Enrolling by invitation
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03574103 on ClinicalTrials.gov ↗ ← All trials in Brazil