Eccentric Muscle Training in Cardiac Rehabilitation

Condition(s) studied

Investigational drug(s) / intervention(s)

eccentric bike training: progressive following protocol, 10min

eccentric overload training: dynamic strength training + eccentric overload, progressive over time, 3sets\*10reps (15-20min)

aerobic treadmill training: aerobic training, progressive over time, 10 min

aerobic bike training: aerobic training, progressive following protocol, 10 min

traditional dynamic strength training: dynamic strength training, progression over time, 15-20 min

Study summary

The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.

Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction.

This study will be delivered in a cardiac rehabilitation setting.

Eligibility

Primary outcome measure(s)

• 1Repetition Maximum (=RM) leg press (kg) — pre (baseline) + post (15 weeks)
  One repetition maximum on leg press device Technogym BioCircuit. The patient is positioned correctly on the leg press (back supported, feet on platform in standardized way so that repeated tests are in the same position). The patiënt performes a maximal push, the load is automatically adjusted by the BioCircuit algorithm. The system identifies the maximum successful single push as the 1RM (kg).
• 1Repetition Maximum (=RM) Low Row (kg) — pre (baseline) + post (15weeks)
  One repetition maximum on the low row device Technogym BioCircuit. The patient sits with chest supported, feet on the ground, and grips the handles with arms extended. The patiënt performes a maximal pull, the load is automatically adjusted by the BioCircuit algorithm. The system identifies the maximum successful single lift as the 1RM (kg).
• 1Repetition Maximum (=RM) chest press (kg) — pre (baseline) + post (15weeks)
  One repetition maximum on chest press device Technogym BioCircuit. The patient is positioned correctly on the chest press (back supported, feet on the ground in standardized way so that repeated tests are in the same position). The patiënt performes a maximal push, the load is automatically adjusted by the BioCircuit algorithm. The system identifies the maximum successful single push as the 1RM (kg).
• 1Repetition Maximum (=RM) vertical traction (kg) — pre (baseline) + post (15weeks)
  One repetition maximum on vertical traction device Technogym BioCircuit. The patient is positioned correctly on the vertical traction (back supported, feet on the ground in standardized way so that repeated tests are in the same position). The patiënt performes a maximal pull, the load is automatically adjusted by the BioCircuit algorithm. The system identifies the maximum successful single push as the 1RM (kg).
• Handgrip strength — pre (baseline) + post (15 weeks)
  The Jamar handgrip dynamometer is used to measure grip strength in a standardized way ( 90° flex elbow, forearm neutral, and wrist slightly extended). 3 trials per hand are performed, with 10seconds rest in between. The average value is recorded as grip strength.
• Isometric Qceps peak torque (Nm) — pre (baseline) + post (15weeks)
  The subject is seated in the Biodex System dynamometer and securely strapped (trunk, pelvis, thigh). The dynamometer axis is aligned with the knee joint axis (lateral femoral epicondyle). The knee is fixed at 60° of flexion (0° = full extension). The lower leg is attached to the lever arm just above the ankle. The subject performs a maximal isometric knee extension (pushing against the immovable arm) for 3seconds. 3 tests are done with 10seconds rest in between. The highest torque value (Nm) recorded is taken as the quadriceps peak torque.

Trial sites (1)

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