Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids

Condition(s) studied

Investigational drug(s) / intervention(s)

Stereo Radiographic EOS Measurements: Healthy control will undergo a stereo radiographic EOS exam with their arm in various positions. 1. Relaxed standing (0 degree of abduction) 2. 45 degree of abduction in the coronal plane 3. 90 degree of abduction in the coronal plane 4. 120 degree of abduction in the coronal plane 5. 45 degree anterior flexion in the sagittal plane 6. 90 degree anterior flexion in the sagittal plane 7. 120 degree of anterior flexion in the sagittal plane 8. 45 degree extension in the sagittal plane

Study summary

Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration.

Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear.

The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.

Eligibility

Primary outcome measure(s)

• Compere In-vivo glenohumeral joint contact patterns in patients using EOS stereo radiographic imaging — 2 years
  Evaluating in-vivo glenohumeral joint contact patterns in patients with different type of osteoarthritic glenoids pre- and post-TSA. Glenohumeral contact areas are compared before and after surgery in patients with osteoarthritic glenoids, using EOS stereo radiographic imaging
• Compere in-vivo glenohumeral joint contact patterns in healthy subjects using EOS stereo radiographic imaging — 2 years
  Evaluating glenohumeral joint contact patterns in healthy subjects and comparing them with patients with osteoarthritic glenoids before patients receive surgery and after patients receive surgery. Glenohumeral contact areas are compared using EOS stereo radiographic imaging
• Pre-operative factor: Humeral Head Migration — 2 years
  Identifying probable pre-operative factors; for example the amount of HHM; on glenohumeral contact area after surgery using pre- and postoperative CT scans.
• Pre-operative factor: Inclination and rotator cuff muscle's quality — 2 years
  Identifying probable pre-operative factors; for example the inclination and rotator cuff muscle's quality; on glenohumeral contact area after surgery using pre- and postoperative CT scans.
• Pre-operative factor: Degree of glenoid version — 2 years
  Identifying probable pre-operative factors; for example the degree of glenoid version; on glenohumeral contact area after surgery using pre- and postoperative CT scans.
• Intra-operative factors: Degree of glenoid orientation correction — 2 years
  Identifying probable intra-operative factors; for example the degree of glenoid orientation correction; on glenohumeral contact area after surgery.
• Intra-operative factors: Joint-line medialization — 2 years
  Identifying probable intra-operative factors; for example the joint-line medialization; on glenohumeral contact area after surgery.
• Amount of osteolysis inside the glenoid vault and around glenoid component — 2 years
  Evaluating the amount of osteolysis inside the glenoid vault and around glenoid component of the patients at least 2 years after surgery

Trial sites (1)

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