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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
Efficacy of ProgenaMatrixโ„ข in the Management of DFUs
NCT06292026Diabetic Foot Ulcer
ProgenaCare Global, LLC
Not applicable
100
Washington
2022-03-14
Recruiting
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
NCT01297400Burns
Skingenix, Inc.
Phase 2
60
Arizona, California, District of Columbia, Iowa
2022-03-11
Active, closed
Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer
NCT05169567Breast Neoplasm, Neoplasm Metastasis
Eli Lilly and Company
Phase 3
368
Arizona, Arkansas, California, Colorado, Florida, Georgia, Hawaii, Illinois
2022-03-11
Recruiting
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
NCT04864054Hepatocellular Carcinoma, Liver Cancer, Adult, Liver Neoplasm, Metastatic Liver Cancer
Eureka Therapeutics Inc.
Phase 1/2
60
California, Kansas, New York, Oregon, Texas, Washington
2022-03-11
Active, closed
A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants โ‰ฅ16 Years of Age With Fabry Disease
NCT05206773Fabry Disease
Sanofi
Phase 3
122
Alabama, California, Florida, Georgia, New York, Ohio, Pennsylvania, Texas
2022-03-11
Recruiting
Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes
NCT04496479End Stage Liver Disease
LyGenesis, Inc.
Phase 2
12
Massachusetts, Texas
2022-03-11
Active, closed
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT05238883Gastric Cancer, Renal Cell Carcinoma, Melanoma, Sarcoma
HiFiBiO Therapeutics
Phase 1
72
Arizona, California, Florida, Minnesota, Missouri, Texas, Virginia
2022-03-10
Recruiting
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
NCT05315700Solid Tumors
ORIC Pharmaceuticals
Phase 1/2
350
California, Connecticut, District of Columbia, Florida, Illinois, Massachusetts, Minnesota, New York
2022-03-10
Active, closed
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
BeOne Medicines
Phase 3
799
California, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky
2022-03-10
Active, closed
Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
NCT05280470Extensive-stage Small-cell Lung Cancer
Daiichi Sankyo
Phase 2
187
Arkansas, Florida, Illinois, Maryland, Massachusetts, Michigan, Missouri, New Jersey
2022-03-09
Recruiting
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
NCT05201781Multiple Myeloma
Janssen Research & Development, LLC
Phase 4
295
Arizona, California, Florida, Georgia, Illinois, Indiana, Kansas, Massachusetts
2022-03-09
Active, closed
Long-Term Follow-Up (LTFU) for Gene Therapy of Leukocyte Adhesion Deficiency-I (LAD-I)
NCT06282432Leukocyte Adhesion Deficiency
Rocket Pharmaceuticals Inc.
Observational
9
California
2022-03-09
Active, closed
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
NCT05064878CDKL5 Deficiency Disorder, Generalized Tonic Clonic Seizure, Epileptic Spasm, Refractory Seizures
Zogenix, Inc.
Phase 3
87
Alabama, California, Colorado, District of Columbia, Georgia, Massachusetts, Michigan, North Carolina
2022-03-08
Recruiting
An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705
NCT05295433Methylmalonic Acidemia
ModernaTX, Inc.
Phase 1/2
56
California
2022-03-08
Active, closed
INTIBIA Pivotal Study
NCT05250908Urinary Incontinence, Urge, Urinary Bladder, Overactive, Urinary Bladder Diseases, Urologic Diseases
Coloplast A/S
Not applicable
208
California, District of Columbia, Florida, Georgia, Idaho, Kansas, Massachusetts, Michigan
2022-03-07
Recruiting
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
NCT05261139COVID-19
Pfizer
Phase 3
160
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Louisiana, Maryland
2022-03-07
Recruiting
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
NCT05091424Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Hoffmann-La Roche
Phase 1
332
Minnesota, New York, Ohio, Texas, Utah
2022-03-07
Recruiting
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
NCT04883411Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy
ReVivo Medical, Corp.
Not applicable
50
New Jersey, New York, Ohio
2022-03-07
Active, closed
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer
NCT05132582HER2 Positive Breast Cancer
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
654
Arizona, Arkansas, California, Florida, Georgia, Illinois, Kentucky, Maryland
2022-03-07
Active, closed
Cardiac Implantable Electronic Device (CIED) Research Study
NCT05061862Arrhythmias, Cardiac, Bradycardia, Tachycardia
Medtronic Cardiac Rhythm and Heart Failure
Observational
1,000
Florida, Georgia, Oregon, Pennsylvania, Virginia
2022-03-06
Active, closed
Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
NCT05215340Metastatic Non Small Cell Lung Cancer
Daiichi Sankyo
Phase 3
740
Arizona, California, Colorado, Maryland, Massachusetts, New Hampshire, New Jersey, New York
2022-03-04
Recruiting
FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
NCT05304962Breast Cancer
Regor Pharmaceuticals Inc.
Phase 1
64
California, Florida, Georgia, Massachusetts, Missouri, New York
2022-03-04
Recruiting
Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects
NCT04775706Short Bowel Syndrome
Hanmi Pharmaceutical Company Limited
Phase 2
18
Massachusetts, Ohio
2022-03-03
Active, closed
Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends
NCT04865679Symptomatic Neuroma, Amputation, Chronic Nerve Pain
Axogen Corporation
Not applicable
15
Massachusetts, Texas
2022-03-02
Recruiting
A Study of Prucalopride in Breastfeeding Women With Constipation
NCT04838522Chronic Idiopathic Constipation (CIC)
Takeda
Observational
12
California
2022-03-02
Recruiting
Trisol System EFS Study
NCT04905017Tricuspid Regurgitation
Trisol Medical
Not applicable
30
California, Georgia, New York, Ohio, Pennsylvania, Tennessee, Virginia
2022-03-02
Active, closed
A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
NCT05090371Relapsing-Remitting Multiple Sclerosis
Novartis Pharmaceuticals
Phase 4
136
Alabama, Arizona, California, Florida, Idaho, Louisiana, Maryland, Massachusetts
2022-03-02
Active, closed
A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)
NCT05119569Relapsing Multiple Sclerosis
Hoffmann-La Roche
Phase 2
109
California, Nevada
2022-03-01
Active, closed
A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis
NCT05250973Amyloidosis
Janssen Research & Development, LLC
Phase 2
151
California, Connecticut, Florida, Georgia, Massachusetts, Michigan, New York, North Carolina
2022-03-01
Recruiting
Multi-analyte Blood Test Clinical Trial
NCT05199259Liver Cirrhosis, Liver Cancer, HCC, Hepatocellular Carcinoma
Helio Genomics
Observational
1,200
California, Florida, Texas
2022-03-01
Recruiting
Inappropriate Sinus Tachycardia Registry
NCT05107635Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome
AtriCure, Inc.
Observational
500
California, Florida, Kansas, Maryland, Ohio, Texas, Utah, Washington
2022-03-01
Active, closed
A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
NCT05243550Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
UroGen Pharma Ltd.
Phase 3
240
Arizona, California, Kansas, Maryland, Missouri, New Jersey, New York, Tennessee
2022-03-01
Recruiting
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
NCT04988555Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, Multiple Myeloma, Myelodysplastic Syndromes
Sumitomo Pharma America, Inc.
Phase 1/2
606
California, Colorado, District of Columbia, Florida, Illinois, Maryland, Massachusetts, New Jersey
2022-02-28
Recruiting
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
NCT05156398Migraine
Pfizer
Phase 3
640
Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Illinois
2022-02-28
Active, closed
A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
NCT05224102Diabetic Macular Edema
Genentech, Inc.
Phase 4
218
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Maryland, Michigan
2022-02-28
Recruiting
MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers
NCT04647240Venous Stasis Ulcer, Venous Leg Ulcer
Merakris Therapeutics
Phase 2
80
Arizona, California, Florida, Louisiana, New York, Ohio, Texas, Virginia
2022-02-26
Active, closed
A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS
NCT05279755Amyotrophic Lateral Sclerosis
ProJenX
Phase 1
72
Massachusetts, Texas
2022-02-26
Active, closed
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen
NCT05185843Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Phase 3
24
California, Florida, Michigan, New York
2022-02-25
Active, closed
A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1)
NCT05222802Glioblastoma Multiforme
Katmai Pharmaceuticals Inc.
Phase 1
52
California, Florida, Massachusetts, Michigan, New York, Ohio, Tennessee, Utah
2022-02-25
Active, closed
Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain
NCT05287373Peripheral Neuralgia, Chronic Pain
Nalu Medical, Inc.
Not applicable
89
Arizona, Arkansas, California, Colorado, District of Columbia, North Carolina, Oregon, Texas
2022-02-23
Recruiting
Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)
NCT04665037Invasive Fungal Infection
Merck Sharp & Dohme LLC
Phase 2
40
California, Florida, Illinois, North Carolina, Texas
2022-02-22
Active, closed
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
NCT05120349Non-Small Cell Lung Cancer
AstraZeneca
Phase 3
390
Alaska, California, Colorado, Delaware, Georgia, Illinois, Maryland, New Jersey
2022-02-21
Active, closed
Setrusumab vs Placebo for Osteogenesis Imperfecta
NCT05125809Osteogenesis Imperfecta
Ultragenyx Pharmaceutical Inc
Phase 2/3
183
Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Illinois
2022-02-21
Active, closed
A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC
NCT05211895Non-Small Cell Lung Cancer
AstraZeneca
Phase 3
791
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Kentucky, Maryland
2022-02-18
Active, closed
Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer
NCT04851613Breast Cancer
Laekna Limited
Phase 3
256
California, Georgia, Iowa, Mississippi, Vermont, Virginia
2022-02-18
Recruiting
Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant
NCT05027906Prevention of Rejection in Kidney Transplant
Eledon Pharmaceuticals
Phase 1/2
48
Ohio
2022-02-18
Active, closed
A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration
NCT05230537Age-Related Macular Degeneration
Novartis Pharmaceuticals
Phase 2
168
California, Colorado, Florida, Indiana, Louisiana, Maryland, Massachusetts, New Jersey
2022-02-17
Recruiting
A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT05128825High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 2
310
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois
2022-02-17
Active, closed
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
NCT05239143Breast Cancer, Ovarian Cancer, Non Small Cell Lung Cancer, Colorectal Cancer
Poseida Therapeutics, Inc.
Phase 1
180
California, Colorado, Iowa, Kansas, Maryland, Massachusetts, Nebraska, New York
2022-02-15
Active, closed
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
NCT05103358Tumor, Tumor, Solid, Metastasis, Metastatic Cancer
Aadi Bioscience, Inc.
Phase 2
120
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii
2022-02-15
Recruiting
Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
NCT05263206Pruritus
Sanofi
Phase 3
284
California, District of Columbia, Florida, Georgia, Indiana, Kentucky, Louisiana, Maryland
2022-02-15
Active, closed
Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis
NCT05138133Lupus Nephritis
AstraZeneca
Phase 3
363
Arizona, California, Florida, Georgia, Kentucky, New Jersey, New York, North Carolina
2022-02-15
Active, closed
A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema
NCT05121376Hereditary Angioedema, HAE
BioMarin Pharmaceutical
Phase 1/2
44
Alabama, Arizona, California, Colorado, Kansas, Maryland, Mississippi, Missouri
2022-02-15
Active, closed
A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)
NCT04573023Mucopolysaccharidosis II
JCR Pharmaceuticals Co., Ltd.
Phase 3
86
Arizona, California, Illinois, Minnesota, New York, North Carolina, Pennsylvania
2022-02-14
Recruiting
Sustained Acoustic Medicine for Osteoarthritis Pain
NCT05254574Osteoarthritis
ZetrOZ, Inc.
Phase 1
200
Florida
2022-02-14
Recruiting
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT05627960Triple Negative Breast Cancer, Hormone-Resistant Breast Cancer, Non Small Cell Lung Cancer, Mesothelioma
A&G Pharmaceutical Inc.
Phase 1
77
Maryland
2022-02-14
Active, closed
Long-term Follow-up Study of Allogeneic Gamma Delta (ฮณฮด) CAR T Cells
NCT04911478Lymphoma, Follicular, Lymphoma, Mantle-Cell, Marginal Zone Lymphoma, Primary Mediastinal B-cell Lymphoma
Adicet Therapeutics
Observational
50
California, Kentucky, Texas, Wisconsin
2022-02-14
Active, closed
177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer
NCT05204927Metastasis From Malignant Tumor of Prostate
Curium US LLC
Phase 3
439
Arizona, California, Florida, Illinois, Maryland, Michigan, Minnesota, Missouri
2022-02-14
Active, closed
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
NCT05383274Urethral Stricture
Urotronic Inc.
Phase 4
34
Arkansas, Florida, Louisiana, Maryland, Nevada, New Jersey, New York, Texas
2022-02-14
Active, closed
A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer
NCT05141721Colorectal Neoplasms
Seattle Project Corporation
Phase 2/3
700
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Illinois, Indiana
2022-02-12
Recruiting
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
NCT06378632Heart Failure
Cordio Medical
Observational
500
Alabama, California, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana
2022-02-11
Active, closed
A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)
NCT05031780Sickle Cell Disease
Agios Pharmaceuticals, Inc.
Phase 2/3
286
California, Connecticut, District of Columbia, Florida, Illinois, Indiana, Louisiana, Maryland
2022-02-11
Recruiting
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors
NCT05269316Solid Tumor, Advanced Solid Tumor
Impact Therapeutics, Inc.
Phase 1/2
61
New Jersey, New York, South Carolina, Texas
2022-02-11
Recruiting
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
NCT04779320Crohn's Disease (CD)
Takeda
Phase 3
120
Arizona, California, Florida, Georgia, Illinois, Indiana, Maryland, Massachusetts
2022-02-10
Active, closed
LIFE-BTK PK Sub-study
NCT05208905Critical Limb Ischemia (CLI)
Abbott Medical Devices
Not applicable
9
Florida, Massachusetts, Oklahoma
2022-02-10
Active, closed
Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc
NCT05258435Cervical Disc Disease, Degenerative Disc Disease
NuVasive
Observational
131
California, Colorado, Florida, Illinois, Indiana, Louisiana, North Carolina, Texas
2022-02-09
Recruiting
US Post-Market Surveillance Study of the Surfacer System
NCT05050799Venous Disease
Merit Medical Systems, Inc.
Observational
30
Arizona, Florida, Georgia, Ohio, Texas, Utah, Virginia
2022-02-08
Active, closed
Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease
NCT05202509Atherosclerotic Cardiovascular Disease
NewAmsterdam Pharma
Phase 3
9,541
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois
2022-02-07
Recruiting
Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma
NCT04879043Multiple Myeloma, Plasma Cell Disorder
Heidelberg Pharma AG
Phase 1/2
78
Georgia, Kentucky, Nebraska, New York, Texas
2022-02-07
Active, closed
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
NCT05221840Non-Small Cell Lung Cancer
AstraZeneca
Phase 3
1,051
California, Connecticut, Florida, Illinois, Indiana, Kentucky, Maryland, Michigan
2022-02-07
Active, closed
Insigniaโ„ข Hip Stem Outcomes Study
NCT05144191Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
Stryker Orthopaedics
Not applicable
313
Arizona, California, Illinois, Nevada, New York, North Carolina, Pennsylvania, Tennessee
2022-02-07
Recruiting
InSpace Accelerated Rehabilitation Study
NCT05329584Rotator Cuff Tears
Stryker Endoscopy
Not applicable
160
Arizona, Arkansas, Colorado, Florida, Georgia, Illinois, Minnesota, New York
2022-02-07
Recruiting
Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
NCT05266417Parkinson Disease
Gateway Institute for Brain Research
Phase 2
56
Florida
2022-02-07
Recruiting
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
NCT05231785Early-Onset Alzheimer Disease
Alnylam Pharmaceuticals
Phase 1
60
California, Indiana
2022-02-04
Active, closed
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)
NCT05173987Endometrial Neoplasms
Merck Sharp & Dohme LLC
Phase 3
280
Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky
2022-02-03
By invitation
A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
NCT05076617Stereotypical Prolonged Seizures
UCB Biopharma SRL
Phase 3
300
Arizona, Arkansas, California, District of Columbia, Florida, Hawaii, Idaho, Illinois
2022-02-03
Recruiting
Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction
Impulse Dynamics
Not applicable
1,500
Alabama, Arizona, California, Connecticut, Florida, Georgia, Indiana, Iowa
2022-02-03
Active, closed
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD)
NCT05063162Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD)
UCB Biopharma SRL
Phase 3
113
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Maryland, Massachusetts
2022-02-02
Active, closed
First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer
NCT05156866Advanced Solid Tumor, Gastric Cancer, Pancreas Cancer, Gastroesophageal Junction Adenocarcinoma
TORL Biotherapeutics, LLC
Phase 1
163
California, Indiana, Missouri, Texas
2022-02-02
Recruiting
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
NCT05070845Primary Immune Thrombocytopenia
Pfizer
Phase 2
91
North Carolina
2022-02-02
Active, closed
Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older
NCT05304351Herpes Zoster, Shingles
Curevo Inc
Phase 2
1,516
Arizona, Florida, Illinois, Kansas, Kentucky, Nevada, Oklahoma, Tennessee
2022-02-02
Active, closed
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)
NCT05262023Frontotemporal Dementia
Denali Therapeutics Inc.
Phase 1/2
85
California, Maryland, Pennsylvania
2022-02-01
Active, closed
A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
NCT05094336Advanced MTAP-null Solid Tumors
Amgen
Phase 1/2
329
California, Florida, Indiana, Maryland, Michigan, Missouri, New Jersey, New York
2022-02-01
Active, closed
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies
NCT05207670Non-Hodgkin Lymphoma
Genentech, Inc.
Phase 2
320
Alabama, Alaska, Arizona, California, Colorado, Delaware, Florida, Iowa
2022-02-01
By invitation
Long-Term Follow-up: Phase I/II Clinical Study to Evaluate the Safety and Efficacy of the Infusion of RP-L102
NCT07527975Fanconi Anemia
Rocket Pharmaceuticals Inc.
Observational
14
California
2022-02-01
Active, closed
Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
NCT04770870Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
DT MedTech, LLC
Not applicable
94
Arkansas, California, Florida, Indiana, Maryland, New Mexico, North Carolina, Oklahoma
2022-02-01
Active, closed
Gene Therapy Study for Children With CLN5 Batten Disease
NCT05228145Neuronal Ceroid Lipofuscinosis CLN5
Neurogene Inc.
Phase 1/2
6
New York
2022-01-31
Active, closed
A Study to Look at the Health Outcomes of Patients With COVID-19 and Influenza
NCT05160636COVID-19, Coronavirus Disease 2019, Influenza
Pfizer
Observational
999
New York
2022-01-31
Recruiting
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
NCT05150691HER2-positive Advanced Solid Tumor
DualityBio Inc.
Phase 1/2
796
California, District of Columbia, Florida, Georgia, Hawaii, Illinois, Louisiana, Maryland
2022-01-31
Active, closed
EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
NCT05263037Chronic Low-back Pain, Anxiety, Depression
AppliedVR Inc.
Not applicable
1,093
California
2022-01-31
Active, closed
Tumor-induced Osteomalacia Disease Monitoring Program
NCT04783428Tumor-induced Osteomalacia (TIO)
Ultragenyx Pharmaceutical Inc
Observational
23
Connecticut, Indiana, Maryland, Tennessee, Virginia
2022-01-31
By invitation
Post Market Clinical Follow-Up Study for EVOLUTIONยฎ NitrXโ„ข Keeled Tibia and EVOLUTIONยฎ NitrXโ„ข CS/CR Femur With Cruciate Sacrificing Insert
NCT04816773Joint Diseases, Osteoarthritis, Arthritis Knee, Avascular Necrosis
MicroPort Orthopedics Inc.
Observational
150
California
2022-01-27
Active, closed
Kerecis Case Registry for SurgiBind : Soft Tissue Reinforcement
NCT05898711Surgery-Complications
Kerecis Ltd.
Observational
200
Virginia
2022-01-27
Active, closed
Study Assessing Long-term Safety and Efficacy of Alpelisib in Patients With PIK3CA-Related Overgrowth Spectrum (PROS) Who Previously Participated in Study CBYL719F12002 (EPIK-P1)
NCT04980833PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals
Phase 2
41
Massachusetts
2022-01-27
Recruiting
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132Advanced Solid Tumor, Non Small Cell Lung Cancer, Untreated Advanced NSCLC, 1st Line NSCLC
Synthekine
Phase 1/2
364
Arizona, California, Connecticut, District of Columbia, Georgia, Illinois, Maryland, Massachusetts
2022-01-25
Recruiting
Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia
NCT05184335Schizophrenia
Reviva Pharmaceuticals
Phase 3
690
Arizona, Arkansas, California, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-01-24
Active, closed
Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis
NCT05203939Retinitis Pigmentosa, Leber Congenital Amaurosis
Ocugen
Phase 1/2
22
Arizona, California, Florida, Georgia, Oregon, Pennsylvania, Texas
2022-01-24
Active, closed
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
NCT05159765Myopia
Visioneering Technologies, Inc
Not applicable
144
California, Illinois, New York, Texas
2022-01-22
Active, closed
Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged โ‰ฅ1 to <7 Years With NF1-related Symptomatic, Inoperable PN
NCT05309668Neurofibromatosis Type 1
AstraZeneca
Phase 1/2
36
Ohio, Pennsylvania, Texas, Virginia
2022-01-21
Active, closed
A Study to Learn About the Effect of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Risdiplam (ASCEND)
NCT05067790Spinal Muscular Atrophy
Biogen
Phase 3
45
Arizona, California, Georgia, Massachusetts, Michigan, New York, North Carolina, Pennsylvania
2022-01-21
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=73

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