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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
NCT05307705Breast Cancer
Eli Lilly and Company
Phase 1
260
Arizona, California, Florida, Georgia, Massachusetts, Minnesota, Missouri, New York
2022-05-11
Recruiting
REMASTer: REcurrent Brain Metastases After SRS Trial
NCT05124912Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
Monteris Medical
Not applicable
261
California, Illinois, Maryland, Missouri, North Carolina, Ohio, Wisconsin
2022-05-10
Active, closed
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.
NCT05109728Glioblastoma
Novartis Pharmaceuticals
Phase 1
63
New York, Pennsylvania, Texas, Wisconsin
2022-05-10
By invitation
Posterior Cervical Fixation Study
NCT04770571Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease
NuVasive
Observational
150
California, Connecticut, Maryland, New York, Pennsylvania, Tennessee, Texas
2022-05-10
Active, closed
Safety of Herpes Zoster Subunit (HZ/su) Vaccine During Pregnancy in Adult Women With Immunocompromised Conditions
NCT05811754Herpes Zoster
GlaxoSmithKline
Observational
2,844
Massachusetts
2022-05-09
Active, closed
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
NCT05069558Stroke, Patent Foramen Ovale, PFO
Occlutech International AB
Not applicable
450
Arizona, California, Colorado, District of Columbia, Illinois, Kentucky, Maine, Massachusetts
2022-05-09
Recruiting
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
NCT04771572Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma, T-cell-prolymphocytic Leukemia
Newave Pharmaceutical Inc
Phase 1
100
Illinois, Massachusetts, North Carolina, Ohio, Texas, Utah
2022-05-08
Active, closed
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
NCT05134012Coronary Artery Disease
MedTrace Pharma A/S
Phase 3
215
Iowa, Minnesota, Missouri, Pennsylvania, Texas, Virginia
2022-05-08
Recruiting
Trial for Treating Painful Degenerative Disc Disease
NCT05287867Degenerative Disc Disease
Regenexx, LLC
Not applicable
42
Colorado
2022-05-06
Active, closed
HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged โ‰ฅ2 Years With Congenital Hyperinsulinism (CHI)
NCT04732416Congenital Hyperinsulinism
Hanmi Pharmaceutical Company Limited
Phase 2
17
Pennsylvania
2022-05-05
Active, closed
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
NCT04960579Multiple Myeloma
Poseida Therapeutics, Inc.
Phase 1
275
Arizona, California, Georgia, Illinois, Iowa, Kansas, Maryland, Michigan
2022-05-05
Recruiting
To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva
NCT05090891Fibrodysplasia Ossificans Progressiva (FOP)
Incyte Corporation
Phase 2
98
Minnesota, Pennsylvania
2022-05-05
Active, closed
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis
NCT05371964Myelofibrosis
Geron Corporation
Phase 1
30
California, Florida, New York, Washington
2022-05-04
Active, closed
RADIANCE Continued Access Protocol
NCT05017935Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc.
Not applicable
300
California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Louisiana
2022-05-04
Active, closed
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
NCT05269004Multiple Sclerosis
Hoffmann-La Roche
Phase 3
1,300
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-05-03
Recruiting
Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix
NCT05197881Cervical Cancer by FIGO Stage 2018
Varian, a Siemens Healthineers Company
Not applicable
125
Alabama, Arkansas, California, Pennsylvania, Texas
2022-05-03
Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
NCT05366881Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer
Adela, Inc
Observational
7,000
California, Florida, Georgia, Indiana, Kentucky, Minnesota, Ohio, Oregon
2022-05-03
Active, closed
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
NCT05280548Fabry Disease
Sanofi
Phase 3
104
Alabama, California, Georgia, Illinois, New York, Texas, Utah, Virginia
2022-05-03
Active, closed
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent ฮฒ-Thalassemia (TDT)
NCT05356195Beta-Thalassemia, Thalassemia, Genetic Diseases, Inborn, Hematologic Diseases
Vertex Pharmaceuticals Incorporated
Phase 3
16
Tennessee
2022-05-03
Active, closed
Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth Restorations
NCT05315414Jaw, Edentulous, Partially
Dentsply Sirona Implants and Consumables
Not applicable
138
Iowa
2022-05-03
Recruiting
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
NCT04879329Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
372
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Massachusetts, Michigan
2022-05-03
Recruiting
Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)
NCT05369052Diabetic Foot Infection
MicuRx
Phase 3
865
California
2022-05-03
Active, closed
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
NCT05329649Sickle Cell Disease, Hydroxyurea Failure, Hydroxyurea Intolerance, Hemoglobinopathies
Vertex Pharmaceuticals Incorporated
Phase 3
13
North Carolina, Pennsylvania, Tennessee
2022-05-02
Active, closed
A Study to Assess Long-term Outcomes of Myocarditis Following Administration of COVID-19 mRNA Vaccine (SPIKEVAX)
NCT06189053Myocarditis
ModernaTX, Inc.
Observational
1,500
Illinois
2022-04-30
Active, closed
EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)
NCT05444894Transfusion Dependent Beta Thalassemia, Hemoglobinopathies, Thalassemia Major, Thalassemia Intermedia
Editas Medicine, Inc.
Phase 1/2
9
California, Minnesota, New York, Ohio, Pennsylvania, Tennessee
2022-04-29
Recruiting
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
NCT04991831Tremor Associated With Tremor Dominant Parkinson's Disease
InSightec
Observational
50
Florida, Illinois, Massachusetts, New York, North Carolina, Ohio
2022-04-28
Recruiting
Cephea Early Feasibility Study
NCT05061004Mitral Regurgitation
Abbott Medical Devices
Not applicable
90
Arizona, California, Georgia, Illinois, Kansas, Michigan, Minnesota, New York
2022-04-28
Recruiting
STOP AF First Post-Approval Study
NCT05227053Paroxysmal Atrial Fibrillation
Medtronic Cardiac Ablation Solutions
Observational
200
Alaska, Connecticut, District of Columbia, Florida, Iowa, Louisiana, Massachusetts, Michigan
2022-04-28
Recruiting
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617Seizures, Lennox Gastaut Syndrome
SK Life Science, Inc.
Phase 3
252
California, Florida, Idaho, Kentucky, Louisiana, Maryland, Minnesota, Missouri
2022-04-28
Active, closed
Evolutโ„ข EXPAND TAVR II Pivotal Trial
NCT05149755Moderate Aortic Valve Stenosis
Medtronic Cardiovascular
Not applicable
650
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Kentucky
2022-04-27
Active, closed
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
NCT05035823Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
Synchron Medical, Inc.
Not applicable
6
New York, Pennsylvania
2022-04-27
Active, closed
A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
NCT05171647Non-Hodgkin Lymphoma
Hoffmann-La Roche
Phase 3
208
California, Missouri, Texas
2022-04-25
Active, closed
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
NCT06809218Post-Intensive Care Syndrome, Sedation
Sedana Medical
Phase 3
312
Tennessee
2022-04-22
Active, closed
Safety and Efficacy of APG-157 in Head and Neck Cancer
NCT05312710Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity, Squamous Cell Carcinoma of the Oropharynx
Aveta Biomics, Inc.
Phase 2
24
California, Florida
2022-04-22
Recruiting
MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
NCT05076760Solid Tumor, Advanced Cancer, Metastatic Cancer, Non Small Cell Lung Cancer
Memgen, Inc.
Phase 1
40
Florida, North Carolina
2022-04-21
Active, closed
US Pilot Study of the CereVascยฎ eShuntยฎ System in Normal Pressure Hydrocephalus
NCT05232838Hydrocephalus, Normal Pressure, Hydrocephalus
CereVasc Inc
Not applicable
50
Connecticut, Florida, Kansas, Kentucky, Massachusetts, New York, Rhode Island, Virginia
2022-04-20
Active, closed
Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors
NCT05352750Advanced Solid Tumor, Soft Tissue Sarcoma Adult
Sonnet BioTherapeutics
Phase 1
42
California
2022-04-20
Active, closed
Use of the Impella BTRโ„ข in Patients With Heart Failure: An Early Feasibility Study
NCT05291884Heart Failure, Acute Decompensated Heart Failure
Abiomed Inc.
Not applicable
10
Georgia, Illinois, Massachusetts, New Jersey, Ohio
2022-04-20
By invitation
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Durvalumab
NCT05303532Cancer
AstraZeneca
Phase 3
214
California, Colorado, Tennessee
2022-04-19
Recruiting
Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
CereGate Inc.
Not applicable
41
California, Colorado, Florida, Illinois, North Carolina, Tennessee, Washington
2022-04-18
Active, closed
Study to Evaluate the Efficacy and Safety of Venglustat in Adult and Pediatric Patients With Gaucher Disease Type 3
NCT05222906Gaucher's Disease Type III
Sanofi
Phase 3
43
Connecticut, Iowa, Texas, Virginia
2022-04-18
Recruiting
(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors
NCT05208047Advanced Gastrointestinal Stromal Tumors, Metastatic Cancer
Cogent Biosciences, Inc.
Phase 3
482
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Illinois, Iowa
2022-04-14
Active, closed
A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)
NCT05288166Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs
Eli Lilly and Company
Phase 3
925
Arizona, Arkansas, California, Colorado, Florida, Georgia, Indiana, Kentucky
2022-04-14
Recruiting
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
NCT05061550Non-small Cell Lung Cancer
AstraZeneca
Phase 2
630
Arkansas, California, Connecticut, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-04-14
Recruiting
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
NCT05131022Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B Cell Lymphoma (DLBCL), Follicular Lymphoma (FL)
Nurix Therapeutics, Inc.
Phase 1
572
California, Colorado, Connecticut, Florida, Georgia, Illinois, Maryland, New York
2022-04-13
Active, closed
CONVERGE Post-Approval Study (PAS)
NCT05393180Chronic Atrial Fibrillation
AtriCure, Inc.
Not applicable
53
California, Connecticut, Florida, Georgia, Kentucky, Maryland, Massachusetts, New Jersey
2022-04-13
Recruiting
To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers
NCT05356741Locally Advanced or Metastatic HER2-Expressing Cancers
Vir Biotechnology, Inc.
Phase 1/2
645
California
2022-04-13
Active, closed
Phase 1/2 Study of Avutometinib (VS-6766) + Sotorasib With or Without Defactinib in KRAS G12C NSCLC Patients
NCT05074810Non Small Cell Lung Cancer, KRAS Activating Mutation
Verastem, Inc.
Phase 1/2
153
Colorado, District of Columbia, Illinois, Maryland, Massachusetts, Michigan, Minnesota, Missouri
2022-04-12
Recruiting
Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
NCT05406167Cancer, Cancer Central Nervous System, Cancer Thoracic, Cancer, Gastrointestinal
RefleXion Medical
Observational
500
California, Connecticut, Pennsylvania, Texas
2022-04-12
Active, closed
Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer
NCT05316155Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC
Phase 1/2
235
Alabama, California, Colorado, Florida, Illinois, Indiana, Kentucky, Louisiana
2022-04-11
Recruiting
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
NCT04829175Stress Urinary Incontinence, Pelvic Organ Prolapse
Ethicon, Inc.
Observational
1,000
Connecticut, North Carolina, Pennsylvania
2022-04-11
Active, closed
Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis
NCT05071716Hepatic Encephalopathy
Bausch Health Americas, Inc.
Phase 3
524
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia
2022-04-07
Active, closed
Butterfly Pivotal Study
NCT05341661BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms (LUTS)
Butterfly Medical Ltd.
Not applicable
245
New York, Texas
2022-04-07
Active, closed
CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung
NCT05306288Lung Cancer
Delfi Diagnostics Inc.
Observational
11,935
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2022-04-07
By invitation
Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy (IgAN)
NCT05248659Immunoglobulin A Nephropathy
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 2/3
600
Alabama, California, Colorado, Florida, Georgia, Massachusetts, Michigan, New York
2022-04-05
Active, closed
Multi-Center Study of ManNAc for GNE Myopathy
NCT04231266GNE Myopathy
Leadiant Biosciences, Inc.
Phase 2
54
California, Iowa, Kansas, Maryland, Massachusetts, Missouri, New York, Ohio
2022-04-05
Active, closed
Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia
NCT05001828Acute Myeloid Leukemia, Adult
Polaris Group
Phase 1
38
Florida, North Carolina, Texas
2022-04-05
Recruiting
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
NCT04627428Dry Age-related Macular Degeneration
Luxa Biotechnology, LLC
Phase 1/2
18
California, Michigan
2022-04-05
Active, closed
Study to Assess the Safety and Immunogenicity of TPOXXยฎ When Administered Orally for 28 Days With JYNNEOS
NCT04957485Smallpox
SIGA Technologies
Phase 2
100
Nebraska, Ohio
2022-04-05
Recruiting
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
NCT05267626Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma, Non-Small Cell Lung Cancer
Aulos Bioscience, Inc.
Phase 1/2
159
Florida, Michigan, Minnesota, Missouri, North Carolina, Tennessee, Texas, Utah
2022-04-04
Active, closed
Gekoโ„ข Cross Therapy Registry - Wound
NCT05007301Wound, Venous Leg Ulcer, Diabetic Foot Ulcer, Arterial Leg Ulcer
Firstkind Ltd
Observational
2,500
New York
2022-04-04
By invitation
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447Diabetic Retinopathy, DR
AbbVie
Phase 2
100
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2022-04-04
Active, closed
Precise Procedural and PCI Plan (P4)
NCT05253677Coronary Artery Disease
CoreAalst BV
Not applicable
1,090
California, Minnesota, New York
2022-04-01
Recruiting
Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL
NCT04872478Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia
Meryx, Inc.
Phase 1
50
Georgia, New York
2022-04-01
Active, closed
A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera
NCT05210790Polycythemia Vera
Protagonist Therapeutics, Inc.
Phase 3
293
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana
2022-04-01
Active, closed
A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
NCT05159700Advanced Solid Tumor, Advanced Solid Malignancies
Zhuhai Yufan Biotechnologies Co., Ltd
Phase 1
39
Colorado, Florida, Ohio, Texas, Virginia
2022-03-31
Recruiting
Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques
NCT05642182Psoriasis
SFA Therapeutics
Phase 1
90
Florida, North Dakota, Pennsylvania
2022-03-31
Active, closed
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
NCT05215574Pancreatic Cancer, Breast Cancer, Gastric Cancer, Non-small Cell Lung Cancer
NGM Biopharmaceuticals, Inc
Phase 1
130
Arizona, California, Florida, Michigan, New York, Oklahoma, Texas
2022-03-31
Recruiting
Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT
NCT04959903Hematological Malignancies
Smart Immune SAS
Phase 1/2
36
New York
2022-03-31
Active, closed
Olorofim Aspergillus Infection Study
NCT05101187Invasive Aspergillosis
F2G Biotech GmbH
Phase 3
225
Alabama, California, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-03-31
Active, closed
Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations
NCT05256290Non-Small Cell Lung Cancer, Advanced Non-Small Cell Squamous Lung Cancer, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Cancer
Black Diamond Therapeutics, Inc.
Phase 1/2
200
Alabama, Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Kansas
2022-03-31
Recruiting
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
NCT05312879Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated
Phase 2/3
466
Alabama, Arizona, Arkansas, California, Connecticut, District of Columbia, Florida, Georgia
2022-03-30
Recruiting
4D-710 in Adult Patients With Cystic Fibrosis
NCT05248230Cystic Fibrosis Lung
4D Molecular Therapeutics
Phase 2
30
Alabama, Arizona, California, Colorado, Florida, Illinois, Kansas, Maryland
2022-03-29
Active, closed
Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)
NCT05232929Spinal Muscular Atrophy
Genentech, Inc.
Phase 4
403
Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Kentucky
2022-03-29
Active, closed
Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)
NCT05270668Diffuse Cutaneous Systemic Sclerosis, Interstitial Lung Disease
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 2
154
Arizona, California, Colorado, Connecticut, District of Columbia, Maryland, Massachusetts, Michigan
2022-03-29
Active, closed
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
NCT05303636Change in Bone Mineral Density, Bone Loss
Insud Pharma
Phase 4
1,536
Arizona, Colorado, Florida, Louisiana, Michigan, Nebraska, North Dakota, Pennsylvania
2022-03-28
Active, closed
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
NCT05196035Chronic Kidney Disease, Proteinuria
Bayer
Phase 3
219
California, Florida, Maryland, Missouri, Ohio, Oregon, Utah, Washington
2022-03-28
Active, closed
Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC
NCT05301842Hepatocellular Carcinoma
AstraZeneca
Phase 3
760
Alabama, Arizona, California, Georgia, Maryland, New Mexico, New York, Tennessee
2022-03-28
Recruiting
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
NCT04895436Chronic Lymphocytic Leukemia (CLL)
AbbVie
Phase 2
75
California, Georgia, Iowa, Massachusetts, Michigan, Minnesota, Mississippi, New Jersey
2022-03-28
Recruiting
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
NCT04928846Non Small Cell Lung Cancer
AbbVie
Phase 3
768
Alabama, Arizona, California, Florida, Georgia, Hawaii, Illinois, Indiana
2022-03-25
Active, closed
Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT05348577Prostate Cancer
AstraZeneca
Phase 3
1,035
Arizona, California, Colorado, Maryland, Minnesota, New Jersey, New York, Ohio
2022-03-25
Recruiting
A Study in Patients With Advanced Cancers
NCT05320588Advanced Cancer, Advanced Solid Tumor, Cancer, Oncology
BiOneCure Therapeutics Inc.
Phase 1/2
332
Texas, Virginia
2022-03-25
Active, closed
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
NCT05317416Multiple Myeloma
Pfizer
Phase 3
854
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Kansas, Michigan
2022-03-25
Active, closed
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)
NCT05224141Small Cell Lung Carcinoma
Merck Sharp & Dohme LLC
Phase 3
460
Alabama, California, Florida, Indiana, Massachusetts, Michigan, Mississippi, Pennsylvania
2022-03-24
Active, closed
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
NCT05135559Haemophilia A and B With and Without Inhibitors
Novo Nordisk A/S
Phase 3
153
California, Colorado, Florida, Georgia, Illinois, Indiana, Louisiana, Missouri
2022-03-24
Recruiting
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
NCT05477576GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor, Gastroenteropancreatic Neuroendocrine Tumor Disease, Neuroendocrine Tumors
RayzeBio, Inc.
Phase 3
338
Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Iowa, Kentucky
2022-03-24
Active, closed
Remote Optimization, Adjustment and Measurement for Deep Brain Stimulation
NCT05269862Parkinson Disease
Abbott Medical Devices
Not applicable
100
Arizona, California, Florida, Illinois, Indiana, Massachusetts, New Hampshire, Ohio
2022-03-24
Recruiting
OssDsignยฎ Spine Registry Study ("Propel")
NCT05329129Degenerative Disc Disease, Spinal Stenosis
OssDsign
Observational
450
California, Connecticut, Florida, Georgia, Illinois, Kentucky, Maryland, Minnesota
2022-03-23
Active, closed
Determination of SpO2 and PR Accuracy Specifications at Rest (71Ag_Vital-0031)
NCT05297500Hypoxia
Nihon Kohden
Observational
12
California
2022-03-23
Active, closed
Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients
NCT05264545Partially Edentulous Maxilla or Mandible
McGuire Institute
Not applicable
100
Colorado, Illinois, Nebraska, Tennessee, Texas, Washington, Wisconsin
2022-03-22
Active, closed
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
NCT05277051Neoplasms
GlaxoSmithKline
Phase 1
152
California, North Carolina, Oklahoma, Pennsylvania, Texas, Utah
2022-03-22
Active, closed
A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma
NCT04980222Lymphoma
Hoffmann-La Roche
Phase 2
46
California, Iowa, Michigan, Missouri, New Jersey, New York, Texas
2022-03-22
Active, closed
R&D Study to Evaluate Cordio's Usability and to Collect Patient Speech Utterances
NCT05876533Chronic Heart Failure
Cordio Medical
Observational
216
Connecticut, Florida, Georgia
2022-03-18
By invitation
Long-Term Follow-up Study
NCT05332054Lymphoma, Non-Hodgkin, Relapsed Non-Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Non-Hodgkin Lymphoma
Caribou Biosciences, Inc.
Observational
150
Alabama, Arizona, California, Colorado, Florida, Georgia, Iowa, Kentucky
2022-03-16
Recruiting
Phase I Human Analytics (HALO) Study
NCT05423860Cardiovascular Diseases, Cancer, Dementia, Traumatic Brain Injury
HALO Diagnostics
Observational
2,000
California
2022-03-16
By invitation
Global Utilization And Registry Database for Improved preservAtion of doNor Livers
NCT05082077Liver Diseases, Liver Dysfunction, Liver Transplant Disorder, Liver Transplant Rejection
Paragonix Technologies
Observational
2,000
Alabama, California, Florida, Georgia, Maryland, Massachusetts, Nebraska, North Carolina
2022-03-15
Active, closed
A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)
NCT05239728Carcinoma, Renal Cell
Merck Sharp & Dohme LLC
Phase 3
1,800
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Indiana, Maryland
2022-03-15
Active, closed
Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)
NCT05248646Immunoglobulin A Nephropathy
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
530
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Iowa
2022-03-15
Recruiting
Physio-Anatomy Clinical Data Collection Study
NCT05312164Coronary Stenosis
Gentuity, LLC
Observational
150
California, Florida, Georgia, Massachusetts, Minnesota, Ohio
2022-03-14
Active, closed
A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors
NCT05262400Breast Cancer, Solid Tumors
Pfizer
Phase 1/2
235
California, Massachusetts, Michigan, Missouri, Texas, Washington
2022-03-14
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=72

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