Zilurgisertib is named as an intervention in 2 current clinical trials in our UK, USA, France, Italy, Canada, Japan, China, Germany, Spain, Netherlands, Brazil, Mexico, South Korea and Australia registers. 1 is recruiting patients now. The most common phase is Phase 1/2. The lead sponsor is Incyte Corporation. The most-studied condition is Anemia.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL5314579, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3), ligand 11888, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva
NCT05090891 · Fibrodysplasia Ossificans Progressiva (FOP)
|
Phase 2 | Recruiting | Incyte Corporation | UK, USA, China, Germany, France, Spain, Italy, Netherlands, Canada, Brazil, Mexico, South Korea, Australia |
|
INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders
NCT04455841 · Anemia, Post-essential Thrombocythemia Myelofibrosis, Post-polycythemia Vera Myelofibrosis
|
Phase 1/2 | Active, closed | Incyte Corporation | UK, USA, France, Italy, Canada, Japan |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| Incyte Corporation | 2 |
A trial with sites in more than one country appears in each of those registers.
2 current trials in our UK, USA, France, Italy, Canada, Japan, China, Germany, Spain, Netherlands, Brazil, Mexico, South Korea and Australia registers name Zilurgisertib (also registered as INCB000928) as a drug or biological intervention, as of the registry sync on 1 October 2026. Completed and withdrawn studies are not counted.
Yes. 1 of the 2 trials is recruiting: 1 with sites in UK, 1 with sites in USA, 1 with sites in France, 1 with sites in Italy, 1 with sites in Canada, 1 with sites in China, 1 with sites in Germany, 1 with sites in Spain, 1 with sites in Netherlands, 1 with sites in Brazil, 1 with sites in Mexico, 1 with sites in South Korea and 1 with sites in Australia. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
The lead sponsor is Incyte Corporation. The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Zilurgisertib works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Zilurgisertib works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Zilurgisertib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 1 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.