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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Study to Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients
NCT06010342Solid Tumor
Teligene US
Phase 2
60
California, Texas
2023-03-16
Active, closed
Study of Novel Treatment Combinations in Patients With Lung Cancer
NCT05633667Lung Cancer, Advanced or Metastatic Non-Small-Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer
Gilead Sciences
Phase 2
192
Arizona, Indiana, Kentucky, Missouri, Ohio, Oregon
2023-03-16
Recruiting
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
NCT05776069Von Willebrand Diseases
Vega Therapeutics, Inc
Phase 1/2
116
California, Colorado, Georgia, North Carolina, Pennsylvania, Tennessee, Texas, Washington
2023-03-16
Active, closed
A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)
NCT05624554Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Merck Sharp & Dohme LLC
Phase 3
300
Arkansas, Florida, Mississippi, Washington
2023-03-16
Active, closed
Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
Merck Sharp & Dohme LLC
Phase 2
129
California, Colorado, Florida, Illinois, Iowa, Kansas, Kentucky, Michigan
2023-03-16
Recruiting
Vivistim Registry for Paired VNS Therapy (GRASP)
NCT05301140Upper Extremity Problem
MicroTransponder Inc.
Observational
1,000
Florida, Illinois, Kansas, Kentucky, New Jersey, New York, Pennsylvania, Texas
2023-03-15
Recruiting
Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis
NCT05201404Hepatocellular Carcinoma, Cirrhosis
Can-Fite BioPharma
Phase 3
471
Texas
2023-03-15
Active, closed
An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases
NCT05732402Lupus Nephritis, Immunoglobulin A Nephropathy, Membranous Nephropathy, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Alpine Immune Sciences, Inc.
Phase 1/2
72
Arizona, California, Colorado, Florida, Georgia, Maryland, Massachusetts, Missouri
2023-03-15
Active, closed
A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody
NCT05662397Solid Tumor, Adult, Relapsed Cancer, Refractory Cancer
HotSpot Therapeutics, Inc
Phase 1/2
77
Florida, Nevada, New York, Oregon, Pennsylvania, Texas
2023-03-15
Recruiting
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
NCT05482893Gastric or Gastroesophageal Junction Adenocarcinoma, Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancer (BTC)
Phanes Therapeutics
Phase 1/2
258
California, Colorado, Iowa, Kentucky, Massachusetts, North Carolina, Pennsylvania, Texas
2023-03-15
Active, closed
Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
NCT05445778Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
AbbVie
Phase 3
520
Alabama, Arizona, California, Florida, Georgia, Illinois, Indiana, Iowa
2023-03-15
Recruiting
A Study of PYX-201 in Advanced Solid Tumors
NCT05720117Solid Tumor, Advanced Solid Tumor
Pyxis Oncology, Inc
Phase 1
330
Arizona, California, Colorado, Florida, Georgia, Illinois, Massachusetts, Missouri
2023-03-14
Recruiting
Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome
NCT05789056Netherton Syndrome
Quoin Pharmaceuticals
Phase 2/3
20
California, Indiana, Massachusetts, Texas
2023-03-14
Recruiting
An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease
NCT05757141Vanishing White Matter Disease
Calico Life Sciences LLC
Phase 1/2
50
Massachusetts, Pennsylvania, Utah
2023-03-13
Recruiting
A Study of ASP1002 in Adults for Treatment of Solid Tumors
NCT05719558Advanced Solid Tumors
Astellas Pharma Global Development, Inc.
Phase 1
798
Connecticut, Florida, Iowa, Kentucky, Michigan, Minnesota, New York, Ohio
2023-03-13
Recruiting
A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy
NCT05696613Primary Membranous Nephropathy
Cerium Pharmaceuticals, Inc.
Phase 3
148
California, Florida, Georgia, Illinois, Iowa, Michigan, New York, Texas
2023-03-13
Recruiting
Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors
NCT05784688Solid Tumor, Biliary Tract Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer
TiumBio Co., Ltd.
Phase 1/2
140
Texas, Washington
2023-03-10
Recruiting
A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
NCT05643742B-cell Lymphoma, Non-Hodgkin Lymphoma, B-cell Malignancy, Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
CRISPR Therapeutics AG
Phase 1/2
120
Kansas, Missouri, Texas, Utah
2023-03-10
By invitation
A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis
NCT05735483Atopic Dermatitis, Eczema
Eli Lilly and Company
Phase 3
333
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Idaho, Illinois
2023-03-09
Active, closed
Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation
NCT05462145Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Kardium Inc.
Not applicable
549
Alabama, Arkansas, California, Florida, Maryland, Michigan, New York, Ohio
2023-03-09
Recruiting
A Study of BLB-201 RSV Vaccine in Infants and Children
NCT05655182Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.
Phase 1/2
137
California, Colorado, Idaho, Kansas, Louisiana, Michigan, Nebraska, Ohio
2023-03-09
Active, closed
Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study
NCT05136820Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Reduced Ejection Fraction (HFrEF)
Occlutech International AB
Not applicable
15
Arizona, New York
2023-03-09
Active, closed
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
NCT05739383Primary Prevention of Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals
Phase 3
14,012
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii
2023-03-09
Active, closed
Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1
NCT05222932Melanoma, Head and Neck Squamous Cell Carcinoma
TILT Biotherapeutics Ltd.
Phase 1
15
New York
2023-03-08
Active, closed
FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases in the Thorax
NCT05524064Bone Metastases in the Thorax
Varian, a Siemens Healthineers Company
Not applicable
10
Illinois, Ohio
2023-03-08
Active, closed
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)
NCT05705349HIV-1 Infection
Merck Sharp & Dohme LLC
Phase 3
537
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Michigan
2023-03-08
Active, closed
Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder
NCT05818943GRIN-related Disorders
GRIN Therapeutics, Inc.
Phase 1
24
Maryland, New York
2023-03-07
Active, closed
A Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung Cancer
NCT05635708Non-small Cell Lung Cancer, Metastatic Non-small Cell Lung Cancer
BeiGene
Phase 2
400
California, Massachusetts, New York, Oregon, Texas
2023-03-07
Active, closed
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
NCT05649748Pulmonary Arterial Hypertension
Insmed Incorporated
Phase 2/3
91
Florida, Illinois, New York, Texas
2023-03-07
Active, closed
A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)
NCT05526755Stage II-IIIB Non-small Cell Lung Carcinoma
AstraZeneca
Phase 2
188
California, Nevada, New York
2023-03-06
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
NCT05677971Alpha1-Antitrypsin Deficiency
Takeda
Phase 3
160
Alabama, Arizona, California, Colorado, Florida, Georgia, Indiana, Iowa
2023-03-06
Active, closed
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)
NCT05606614Rett Syndrome
Taysha Gene Therapies, Inc.
Phase 3
17
California, Illinois, Maryland, Massachusetts, Missouri, Texas
2023-03-06
Recruiting
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
NCT05327062Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
XSpline S.p.A.
Not applicable
150
Illinois, Massachusetts, North Carolina
2023-03-06
Active, closed
A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma
NCT05625399Melanoma
Bristol-Myers Squibb
Phase 3
579
Arizona, Arkansas, California, Colorado, Florida, Maryland, Minnesota, Nebraska
2023-03-06
Active, closed
AMX0035 in Adult Patients With Wolfram Syndrome
NCT05676034Wolfram Syndrome
Amylyx Pharmaceuticals Inc.
Phase 2
12
Missouri
2023-03-03
Recruiting
Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas
NCT05768919Glioblastoma
SignPath Pharma, Inc.
Phase 1/2
30
District of Columbia, Maryland
2023-03-03
Recruiting
A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies
NCT05753722Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer, NSCLC
Incendia Therapeutics
Phase 1
270
Arizona, Connecticut, Massachusetts, Oregon, Pennsylvania, Tennessee, Texas, Virginia
2023-03-03
Recruiting
Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia
NCT05640102Waldenstrom Macroglobulinemia
BeiGene
Observational
111
Alabama, California, Mississippi, Nevada
2023-03-03
Active, closed
Camera Qualification Study
NCT05808699Diabetic Retinopathy
Digital Diagnostics, Inc.
Observational
626
California, Florida, Mississippi, Montana, North Dakota, Texas
2023-03-03
Active, closed
A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer
NCT05654623Advanced Breast Cancer
Pfizer
Phase 3
624
California, Connecticut, Florida, Illinois, Kentucky, Louisiana, Mississippi, Missouri
2023-03-03
Active, closed
Effect of AIV007 by Periocular Administration in Subjects with Macular Edema Secondary to Neovascular Age-related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME)
NCT05698329Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Macular Edema
AiViva BioPharma, Inc.
Phase 1
19
California, Oregon, Texas
2023-03-02
Active, closed
Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)
NCT05639114Systemic Lupus Erythematosus
Novartis Pharmaceuticals
Phase 3
436
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2023-03-02
Active, closed
The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study
NCT05489588Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
165
California, Connecticut, District of Columbia, Florida, Illinois, Massachusetts, Michigan, New Jersey
2023-03-02
Active, closed
Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma
NCT05607953Locally Advanced Pancreatic Adenocarcinoma
TriSalus Life Sciences, Inc.
Phase 1
60
Texas
2023-03-01
Active, closed
Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects
NCT05509608Electrode Site Reaction
RetMap, Inc
Phase EARLY_PHASE1
90
Illinois
2023-03-01
Active, closed
Impact of a Health Technology Intervention on Patient Activation in Multiple Myeloma
NCT05673083Multiple Myeloma in Relapse, Multiple Myeloma, Multiple Myeloma, Refractory, Multiple Myeloma With Failed Remission
All4Cure
Observational
200
Arkansas, Florida, Iowa, New York, Oklahoma, Texas, Washington
2023-03-01
Active, closed
REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels
NCT05669755Cardiovascular Disease
Novo Nordisk A/S
Phase 3
7,101
Alabama, Arizona, California, Connecticut, Florida, Georgia, Idaho, Illinois
2023-03-01
Active, closed
Patterned Multichannel Vibrotactile Stimulation for the Longitudinal Treatment of Moderate Stage Parkinson's Disease
NCT05830110Parkinson's Disease
Synergic Medical Technologies, Inc.
Not applicable
30
Oregon
2023-03-01
Recruiting
A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma
NCT05456256Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Lantern Pharma Inc.
Phase 2
90
California, Pennsylvania, Texas, Virginia
2023-03-01
Active, closed
TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)
NCT05573555Breast Cancer
Pfizer
Phase 1/2
20
California, Florida, Illinois, Massachusetts, Missouri
2023-03-01
Active, closed
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
NCT05738486Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases
Eli Lilly and Company
Phase 3
1,175
Arizona, California, Florida, Georgia, Massachusetts, Michigan, New Jersey, Rhode Island
2023-02-28
Active, closed
Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.
NCT05201066Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic
Novartis Pharmaceuticals
Phase 2
33
Oregon, Utah
2023-02-28
Active, closed
A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)
NCT05398341Anterior Cruciate Ligament Injuries
Miach Orthopaedics
Observational
300
California, Colorado, Florida, New Jersey, New York, North Carolina, Oregon
2023-02-28
Active, closed
Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors
NCT05651022Solid Tumor, Adult, HCC - Hepatocellular Carcinoma, CRC (Colorectal Cancer), Pancreatic Adenocarcinoma
Indaptus Therapeutics, Inc
Phase 1/2
120
California, Georgia, Michigan, Missouri, New Jersey, New York, Ohio, Pennsylvania
2023-02-28
Active, closed
Efficacy and Safety of ATX01 in Adult Patients With CIPN (Chemotherapy-induced Peripheral Neuropathy)
NCT05593614Chemotherapy-induced Peripheral Neuropathy
AlgoTherapeutix
Phase 2
276
Florida, Kansas, Maryland, New York, Texas
2023-02-28
Active, closed
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
NCT05566795Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc.
Phase 3
418
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2023-02-27
Active, closed
Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness
NCT06138613Motion Sickness
Vanda Pharmaceuticals
Phase 3
705
California
2023-02-27
Recruiting
A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata
NCT05723198Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases
Eli Lilly and Company
Phase 3
595
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana
2023-02-27
Recruiting
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
NCT05666960Ulcerative Colitis Chronic Mild, Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic, Ulcerative Colitis
Rise Therapeutics LLC
Phase 1
36
California, Florida, Minnesota
2023-02-27
Active, closed
A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)
NCT05668741Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Phase 1/2
26
Alabama, California, Colorado, Kansas, Maryland, Massachusetts, Minnesota, Missouri
2023-02-27
Active, closed
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
NCT05094089Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
W.L.Gore & Associates
Observational
320
Georgia, Massachusetts, Michigan, New Mexico, New York, North Carolina, South Carolina, Virginia
2023-02-24
Recruiting
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
NCT05471856Solid Tumors
Boehringer Ingelheim
Phase 1
66
California, Connecticut, New Jersey
2023-02-24
Active, closed
Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy
NCT06018558Geographic Atrophy
Ocugen
Phase 1/2
60
Arizona, Florida, Indiana, Mississippi, Missouri, New Jersey, North Carolina, Pennsylvania
2023-02-23
Active, closed
TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)
NCT05548127Breast Cancer
Pfizer
Phase 1/2
37
California, Florida, Illinois, Missouri, Texas, Washington
2023-02-23
Active, closed
Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis
NCT05182749Shigellosis
Intralytix, Inc.
Phase 1/2
52
Maryland
2023-02-23
By invitation
An Extension Study of JR-141 to Evaluate the Long-term Safety and Efficacy in MPS II (Hunter Syndrome) Subjects
NCT05594992Mucopolysaccharidosis II
JCR Pharmaceuticals Co., Ltd.
Phase 3
80
California, Pennsylvania
2023-02-22
Active, closed
Investigation of DEXA-C Anterior Cervical Interbody System
NCT05883436Degenerative Disc Disease
Aurora Spine and Pain
Not applicable
71
California, Kentucky, Louisiana, Oklahoma
2023-02-22
Recruiting
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
NCT05651932Multiple Myeloma, Myeloma, Myeloma Multiple
K36 Therapeutics, Inc.
Phase 1
165
California, Florida, Georgia, Massachusetts, Minnesota, New Jersey, New York, North Carolina
2023-02-22
Active, closed
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age
NCT05741476Allergy, Peanut
DBV Technologies
Phase 3
600
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2023-02-21
Active, closed
Study With Various Immunotherapy Treatments in Participants With Lung Cancer
NCT05676931Advanced Non-Small Cell Lung Cancer
Gilead Sciences
Phase 2
400
Alabama, California, Florida, Illinois, Louisiana, Michigan, Virginia, Washington
2023-02-21
Recruiting
VIrtual STudy in Achondroplasia for the US (VISTA)
NCT06168201Achondroplasia
BioMarin Pharmaceutical
Observational
170
California, Maryland, North Carolina, Ohio, South Dakota, Texas, Wisconsin
2023-02-21
Recruiting
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
NCT05503797Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors
Fore Biotherapeutics
Phase 2
254
California, Connecticut, Florida, Maryland, Massachusetts, Minnesota, Missouri, Nebraska
2023-02-21
Active, closed
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051)
NCT05631093HIV-1 Infection
Merck Sharp & Dohme LLC
Phase 3
553
California, District of Columbia, Florida, Georgia, New Jersey, Pennsylvania, Texas
2023-02-20
Active, closed
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052)
NCT05630755HIV-1 Infection
Merck Sharp & Dohme LLC
Phase 3
514
Arizona, California, District of Columbia, Florida, Georgia, Massachusetts, Michigan, Missouri
2023-02-17
By invitation
Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C
NCT05905926Irritable Bowel Syndrome With Constipation (IBS-C)
Ardelyx
Phase 3
150
Alabama, California, Florida, Illinois, Indiana, Maine, Minnesota, Nebraska
2023-02-17
Active, closed
A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome
NCT05690386Turner Syndrome
Ascendis Pharma Endocrinology Division A/S
Phase 2
48
California, Colorado, Florida, Georgia, Idaho, Illinois, Massachusetts, Minnesota
2023-02-15
Active, closed
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
NCT05702034Ischemic Stroke; Ischemic Attack, Transient
Janssen Research & Development, LLC
Phase 3
12,523
Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2023-02-15
Active, closed
A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months
NCT05743881Respiratory Syncytial Virus, Human Metapneumovirus
ModernaTX, Inc.
Phase 1
186
California, District of Columbia, Illinois, Louisiana, North Carolina, Rhode Island, South Carolina, Tennessee
2023-02-15
Recruiting
Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
NCT05518188Spasticity, Muscle, Microcephaly, Intellectual Deficiency, Growth Retardation
Elpida Therapeutics SPC
Phase 1/2
4
Texas
2023-02-15
Recruiting
A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer
NCT05683418HR+/HER2-negative Breast Cancer
Totus Medicines
Phase 1
241
Illinois, Massachusetts, Nevada, Pennsylvania, Tennessee, Texas, Virginia
2023-02-15
Active, closed
A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77)
NCT05722015Metastatic Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
377
Arizona, Florida, Illinois, Indiana, Kentucky, Mississippi, Missouri
2023-02-14
Active, closed
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
NCT05711940Treatment Resistant Depression
COMPASS Pathways
Phase 3
572
Arizona, California, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota
2023-02-14
Recruiting
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
Phase 3
160
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Hawaii
2023-02-14
Active, closed
(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
NCT05607004Breast Neoplasms, Invasive Breast Cancer, Estrogen-receptor-positive Breast Cancer, HER2-negative Breast Cancer
Atossa Therapeutics, Inc.
Phase 2
87
Arizona, California, Florida, Illinois, Kentucky, Michigan, Minnesota, Missouri
2023-02-14
Active, closed
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238Haemophilia A, Haemophilia A With Inhibitors
Novo Nordisk A/S
Phase 3
451
California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Michigan
2023-02-13
Active, closed
Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL
NCT05555862Anal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition, AIN 2/3, HPV Infection
Frantz Viral Therapeutics, LLC
Phase 2
17
Illinois, New York
2023-02-10
Recruiting
Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT05739981Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Imunon
Phase 1/2
30
Maryland, New York, Oklahoma, Texas
2023-02-10
Recruiting
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
NCT05682378Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
Phase 3
195
Florida, New York, Ohio, Pennsylvania, Utah
2023-02-10
Active, closed
Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
NCT05605899High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company
Phase 3
300
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Iowa
2023-02-10
Recruiting
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
NCT05519475Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Regeneron Pharmaceuticals
Phase 2
120
Arizona, California, Colorado, Florida, Indiana, Louisiana, Maryland, Mississippi
2023-02-09
Active, closed
A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy
NCT05621317Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis, Immune System Diseases
Aravax Pty Ltd
Phase 2
90
Arkansas, California, Georgia, Indiana, Maryland, Massachusetts, North Carolina
2023-02-09
Recruiting
Home Sleep Therapy for Older Adults With MCI
NCT05771844Mild Cognitive Impairment, Sleep, Transcranial Electrical Stimulation, Machine Learning
Brain Electrophysiology Laboratory Company
Not applicable
60
North Carolina, Oregon
2023-02-08
Active, closed
A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
NCT05578976Diffuse Large B-Cell Lymphoma
Genmab
Phase 3
900
Arizona, Arkansas, California, Colorado, Florida, Hawaii, Illinois, Indiana
2023-02-08
Active, closed
A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors
NCT05731271Locally Advanced Solid Tumor, Metastatic Tumor, Colorectal Adenocarcinoma
Transcenta Therapeutics (Hangzhou) Co., Ltd.
Phase 1/2
111
Oregon, Texas
2023-02-08
Recruiting
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
NCT05518578Epilepsy, Seizures, Epileptic
Supernus Pharmaceuticals, Inc.
Phase 2
60
Florida
2023-02-07
Active, closed
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
NCT05797896Dry Age-related Macular Degeneration, Geographic Atrophy, Retinal Disease, Macular Degeneration
Complement Therapeutics
Observational
250
California, Indiana, Maryland, Nevada, Oregon, Pennsylvania, Texas
2023-02-07
Active, closed
A Study to Evaluate RO7204239 in Participants With Facioscapulohumeral Muscular Dystrophy
NCT05548556Facioscapulohumeral Muscular Dystrophy (FSHD)
Hoffmann-La Roche
Phase 2
51
California, Colorado, Kansas, Maryland
2023-02-07
Recruiting
CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
NCT05722418Relapsed/Refractory Multiple Myeloma
Caribou Biosciences, Inc.
Phase 1
50
Alabama, Colorado, Florida, Kentucky, New Jersey, New York, North Carolina, Ohio
2023-02-06
Active, closed
Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)
NCT05609968Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
Phase 3
614
Alabama, California, Florida, Georgia, Louisiana, Michigan, Minnesota, New York
2023-02-06
Active, closed
An English/Spanish Mobile Augmented Reality Pain Assessment App for Hispanic/Latino Pediatric Cancer Patients
NCT06635434Pain, Pediatric Cancer
ALTality, Inc.
Phase EARLY_PHASE1
16
Texas
2023-02-05
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=65

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