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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
NCT07070232Advanced Solid Tumor
BioNTech SE
Phase 1/2
1,438
Arizona, California, Connecticut, Florida, Georgia, Massachusetts, Michigan, New York
2025-08-12
Recruiting
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
NCT07380412ADHD, Sleep Disturbance, Brain Fog
Outliers, Inc.
Not applicable
90
Nevada
2025-08-12
Recruiting
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
NCT07096674Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
Phase 2
90
Alabama, California, Florida, Georgia, Michigan, Nevada, North Carolina, Ohio
2025-08-12
Recruiting
Self-balancing Personal Exoskeleton for SCI (WINY)
NCT07222033Spinal Cord Injury, Paraplegia and Tetraplegia
Wandercraft
Not applicable
12
New York
2025-08-11
Recruiting
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
NCT06979596Malignant Neoplasm
Merck Sharp & Dohme LLC
Phase 2
250
Alaska, Florida, Louisiana, Nebraska, New Jersey, New York, Ohio, Texas
2025-08-11
Recruiting
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
NCT07099898Neoplasms, Lung
GlaxoSmithKline
Phase 3
420
California, North Carolina
2025-08-11
Active, closed
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
NCT07076199Diabetes Mellitus, Type 1
Novo Nordisk A/S
Phase 3
877
Alabama, California, Colorado, Florida, Georgia, Idaho, Illinois, Indiana
2025-08-11
Recruiting
Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults
NCT06988618Prurigo Nodularis
Galderma R&D
Observational
600
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana
2025-08-11
Recruiting
A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs
NCT06908928Triple Negative Breast Cancer
Mabwell (Shanghai) Bioscience Co., Ltd.
Phase 1
52
California, Colorado, Illinois, Massachusetts, New York
2025-08-11
Recruiting
Study of MAR002 in Healthy Men
NCT07195175Acromegaly
Marea Therapeutics
Phase 1
45
Arizona
2025-08-11
Recruiting
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM0504 Tablets in Non-diabetic Overweight or Obese Adult Subjects
NCT07166081Non-diabetic Overweight or Obese
BrightGene Bio-Medical Technology Co., Ltd.
Phase 1
80
Maryland
2025-08-11
Recruiting
Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study
NCT07264426Chronic Inflammatory Demyelinating Polyradiculoneuropathy, CIDP, CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy)
argenx
Observational
200
North Carolina
2025-08-11
Recruiting
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
NCT06927739Acute Coronary Syndromes, Coronary Arterial Disease (CAD), Inflammation, Heart Disease
Abcentra
Phase 2
240
California, Florida, Indiana, Kentucky, Maryland, Michigan
2025-08-11
Recruiting
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
NCT07105098Schizophrenia
Neurocrine Biosciences
Phase 3
284
California, Georgia, Ohio
2025-08-11
Recruiting
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
NCT07122986Healthy Participants
Pfizer
Phase 1
310
California, Florida, New York, Ohio, Tennessee
2025-08-11
Recruiting
A Long-Term Study of JNT-517 in Participants With Phenylketonuria
NCT06628128Phenylketonuria (PKU)
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
240
Florida, Oregon, Pennsylvania, Texas, Utah
2025-08-11
Recruiting
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT
NCT05337241Refractory Ventricular Tachycardia
Thermedical, Inc.
Not applicable
130
Alabama, Pennsylvania, South Carolina, Tennessee, Utah
2025-08-09
Recruiting
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
NCT07172516Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
Xenon Pharmaceuticals Inc.
Phase 3
400
Arizona, Arkansas, California, Florida, Georgia, Illinois, Missouri, Nevada
2025-08-08
Recruiting
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
NCT06699849Sickle Cell Disease Vaso-occlusive Crisis
CSL Behring
Phase 2
70
California, Florida, Georgia, Illinois, Kentucky, Maryland, Michigan, Missouri
2025-08-07
Recruiting
REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam
NCT02880163Hemorrhagic Shock, Trauma, Exsanguinating Hemorrhage, Shock; Traumatic
Arsenal Medical, Inc.
Not applicable
40
Alabama, Ohio
2025-08-07
Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
NCT07094516Alzheimer's Disease
Novartis Pharmaceuticals
Phase 2
407
Arizona, California, Florida, Hawaii, Kansas, Massachusetts, Missouri, Nevada
2025-08-07
Recruiting
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06896916Multiple Myeloma
AbbVie
Phase 1
135
California, Colorado, Missouri, New Jersey, New York, North Carolina, Washington
2025-08-07
Recruiting
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
NCT07098338Non-Small Cell Lung Cancer
AstraZeneca
Phase 2
278
California, Georgia, Maryland, Texas, Virginia
2025-08-07
Not yet open
Optical Coherence Tomography (OCT) Based Intraoral Scanner
NCT07092592The Focus of the Study is to Evaluate the Efficacy of OCT in Scanning and Reconstructing General Tooth and Gum Anatomy, Tooth Anatomy, Gingival Anatomy
Perceptive Technologies, Inc
Observational
70
Massachusetts
2025-08-07
Recruiting
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism
NCT07007793Primary Hyperaldosteronism
AstraZeneca
Phase 3
250
California, Connecticut, Illinois, Maryland, Massachusetts, Michigan, Minnesota, Mississippi
2025-08-07
Active, closed
A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant
NCT07092865Respiratory Syncytial Virus Infections
GlaxoSmithKline
Phase 2
168
Kentucky, Missouri, Nebraska, New York, Pennsylvania, Texas
2025-08-06
Recruiting
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
NCT06952803Prostate Cancer
AstraZeneca
Phase 3
700
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Maryland
2025-08-06
Recruiting
ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors
NCT07158918Solid Tumors
ABL Bio, Inc.
Phase 1/2
65
Ohio
2025-08-06
Active, closed
Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage
NCT06655207Post Partum Haemorrhage, Maternal Care Patterns, High Risk Pregnancy
Baymatob Operations Pty Ltd
Not applicable
1,000
Colorado, Louisiana, New York, Ohio, Pennsylvania
2025-08-06
Recruiting
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
NCT07114601Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm, Endometrial Neoplasms
Eli Lilly and Company
Phase 1
421
California, Florida, Georgia, Massachusetts, Michigan, Missouri, New York, Pennsylvania
2025-08-06
Recruiting
A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer
NCT06774131Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma
UroGen Pharma Ltd.
Phase 3
70
Alabama, Arizona, Arkansas, California, District of Columbia, Florida, Iowa, Nebraska
2025-08-06
Recruiting
A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
NCT06624644Melanoma (Skin Cancer), Melanoma Stage IIIB-IV, Cutaneous Melanoma, Unresectable Melanoma
Linnaeus Therapeutics, Inc.
Phase 2/3
135
California, Colorado, Florida, Massachusetts, New Mexico, Pennsylvania
2025-08-06
By invitation
Acolyte CTO-PCI Study: Imaging and Catheter System to Treat Patients With Coronary Chronic Total Occlusion, Who Have Persistent Symptoms Following Medical Therapy and Are Undergoing Percutaneous Coronary Interventional Procedures
NCT06795763Coronary Chronic Total Occlusions, Ischemic Heart Disease, Ischemic Heart Disease (IHD), Ischemic Heart Disease Chronic
Elumn8 Medical
Not applicable
115
Georgia, Minnesota, New York, Texas
2025-08-06
Recruiting
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
NCT07088068Type 1 Diabetes Mellitus
Sanofi
Phase 3
723
Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho, Kentucky
2025-08-06
Recruiting
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
NCT07029581Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
Phase 2
180
California, Colorado, District of Columbia, Florida, Hawaii, Illinois, Kansas, New York
2025-08-06
Recruiting
A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.
NCT07021898Metastatic Solid Tumors
Erasca, Inc.
Phase 1
200
Tennessee, Texas, Washington
2025-08-06
Active, closed
Rapamycin and Infection-related Illness
NCT07054320Infectious Diseases
Hoskinson Health and Wellness Clinic
Observational
15
Wyoming
2025-08-06
Recruiting
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
NCT07062965Breast Cancer
Pfizer
Phase 3
400
Arizona, California, Colorado, Connecticut, District of Columbia, Georgia, Illinois, Maryland
2025-08-05
Active, closed
A Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and ฮฒ-cell Function in Participants With Type 2 Diabetes Mellitus
NCT07160257Type 2 Diabetes Mellitus
Amgen
Phase 1
56
California
2025-08-05
Recruiting
Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata
NCT07133308Alopecia Areata
Sun Pharmaceutical Industries, Inc.
Phase 3
355
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho
2025-08-05
Recruiting
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
NCT06113237Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
Jazz Pharmaceuticals
Observational
50
West Virginia
2025-08-05
Recruiting
The Effect Cranberry-Based Products on the Female Microbiome
NCT07109713Vaginal Microbiome, Gut Microbiome, Gut Health
Ocean Spray Cranberries, Inc.
Not applicable
60
Illinois
2025-08-05
Recruiting
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease
NCT06607458Refractory Metastatic Colorectal Cancer
Delcath Systems Inc.
Phase 2
90
California, Florida, Kansas, Louisiana, Utah
2025-08-05
Recruiting
FiberLockerยฎ System Augmentation of Rotator Cuff Repairs
NCT06918041Rotator Cuff Tear, Rotator Cuff Tears, Rotator Cuff Tears of the Shoulder
ZuriMED Technologies Inc.
Not applicable
60
Illinois, Maryland, North Carolina, Oregon
2025-08-05
Recruiting
Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease
NCT06825559Cholestatic Liver Disease
Zydus Therapeutics Inc.
Phase 1
6
Indiana
2025-08-05
Active, closed
Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease
NCT06876363X-Linked Chronic Granulomatous Disease
Ensoma
Phase 1/2
15
California, Florida, Massachusetts, Minnesota, New York, North Carolina, Utah
2025-08-05
Recruiting
Cholate Clearance in Fontan and Heart Failure
NCT07009132Fontan, Right Heart Failure
HepQuant, LLC
Observational
75
Pennsylvania
2025-08-04
Active, closed
Safety and Effectiveness of TurbAlignโ„ข for Middle Turbinate Medialization After Functional Endoscopic Sinus Surgery
NCT07027267Sinus Endoscopic Surgery, Turbinate
Spirair, Inc
Not applicable
50
Illinois, Louisiana, Texas
2025-08-04
By invitation
Health and Financial Impact on the Use of a Personal Exoskeleton in the Home and Community: a Case Study
NCT07030322Spinal Cord Injury
Ekso Bionics
Observational
5
California
2025-08-04
Recruiting
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
NCT07089888Tophaceous Gout
Crystalys Therapeutics
Phase 3
250
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2025-08-04
Recruiting
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
NCT07139743Progressive Multiple Sclerosis
Autolus Limited
Phase 1
18
California
2025-08-04
Recruiting
A Study of Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation
NCT07060989Advanced Solid Tumors
Nutshell Therapeutics (Shanghai) Co., LTD.
Phase 1/2
220
Texas
2025-08-04
Recruiting
A Study Evaluating OBI-902 in Participants With Advanced Solid Tumors
NCT07124117Advanced Solid Tumor
OBI Pharma, Inc
Phase 1/2
147
California, Texas
2025-08-04
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
NCT07145918Schizophrenia
AbbVie
Phase 2
268
Arkansas, California, Maryland, New Jersey, Texas
2025-08-04
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
NCT07005102Non-Squamous Non-Small Cell Lung Cancer
AbbVie
Phase 2/3
854
Arizona, California, Colorado, Florida, Hawaii, Iowa, Nebraska, Nevada
2025-08-03
Recruiting
Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC
NCT07098988Metastatic Non-Squamous Non-Small Cell Lung Cancer, Adult Solid Tumor
CatalYm GmbH
Phase 2
107
Alabama, California, Connecticut, Florida, New York, North Carolina, South Carolina
2025-08-01
Recruiting
A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
NCT06997029Advanced Solid Tumor, Advanced Breast Cancer, Advanced Ovarian Cancer
Bristol-Myers Squibb
Phase 1
234
Alabama, California, Colorado, Massachusetts, Missouri, New Hampshire, New York, Texas
2025-08-01
Recruiting
Study Evaluating the Efficacy and Safety of Artesunate
NCT06853184CMV Infection
Amivas Inc.
Phase 2
90
Massachusetts, Minnesota
2025-08-01
Recruiting
Scalable Intervention for Stress Management
NCT07127575Stress, Diaphragmatic Breathing
Livotion, LLC
Not applicable
60
Indiana
2025-08-01
Recruiting
An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms
NCT07078682Uterine Fibroids, Leiomyoma, Menstrual Pain
Zenchi, Inc.
Not applicable
42
Nevada
2025-08-01
Recruiting
OM336 in Autoimmune Cytopenias
NCT07083960AIHA - Warm Autoimmune Hemolytic Anemia, AIHA - Cold Autoimmune Hemolytic Anemia, ITP - Immune Thrombocytopenia
Lakefront Biotherapeutics West LLC
Phase 1
32
California, District of Columbia, Michigan, Washington
2025-08-01
Recruiting
R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
NCT06398418Solid Tumor, Adult, Solid Tumor, Melanoma, Basal Cell Cancer
Rise Therapeutics LLC
Phase 1
33
Colorado, Tennessee
2025-08-01
Recruiting
A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)
NCT06557460Dry Age-related Macular Degeneration, Geographic Atrophy
Regenerative Patch Technologies, LLC
Phase 2
24
California, Illinois, Texas
2025-08-01
Recruiting
PumaRx Registry Trial
NCT06805461Solid Tumors
RenovoRx
Observational
1,000
Florida, Pennsylvania, Vermont
2025-08-01
Recruiting
Continuous Glucose Monitoring, Diabetes Education, and Peer Support for Management of Uncontrolled Type 2 Diabetes
NCT07054125Type 2 Diabetes Mellitus - Poor Control
Whole Endo
Observational
100
North Carolina
2025-08-01
Recruiting
Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
NCT07136623Pulmnary Hypertension
Eko Devices, Inc.
Observational
1,513
California, North Carolina
2025-08-01
Recruiting
A Study of Dotinurad Versus Allopurinol in Participants With Gout
NCT07089875Gout
Crystalys Therapeutics
Phase 3
500
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2025-08-01
Not yet open
PGx Medication Safety Reviews of Persons With IDD
NCT07092852Intellectual Disability, Mild, Intellectual Disability, Mild to Moderate, Developmental Disability
GalenusRx, Inc.
Observational
700
Florida, New York
2025-08-01
Recruiting
Severe Label Expansion for EVO Products Trial
NCT07090395Obstructive Sleep Apnea
ProSomnus Sleep Technologies
Not applicable
49
New York, Texas
2025-08-01
Recruiting
Autologous Adipose Cells Therapy
NCT06869252Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines
CERM INC.
Phase 1/2
40
Delaware
2025-08-01
Recruiting
Evaluation of Accuracy of the Owlet OSS 3.0 Sensor in the Neonatal Population
NCT06771206Pulse Oximeter Validation
Owlet Baby Care, Inc.
Not applicable
20
Alabama, Minnesota
2025-08-01
Recruiting
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
NCT07044336Endometrial Cancer, Malignant Solid Tumour
AstraZeneca
Phase 3
800
Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Indiana, Maine
2025-08-01
Not yet open
Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples
NCT06531031Bloodstream Infection, Sepsis, Septic Shock
Microbio Co Ltd
Observational
1,500
Indiana, Maryland, New Mexico, Tennessee, Texas
2025-08
Not yet open
Seravue Validation Study for Hepatocellular Carcinoma (HCC) Diagnosis
NCT06994130Hepatic Cancer
ImCare Biotech
Observational
1,392
Massachusetts
2025-08
Not yet open
Pharmacokinetic and Safety Study of Metronidazole Oral Suspension in Pediatric Patients With Anaerobic Bacterial Infection
NCT07146217Bacterial Infections
Saptalis Pharmaceuticals LLC
Phase 2
30
Florida, Texas
2025-08
Recruiting
Evaluating Patient Reported Outcomes and Surgeon Satisfaction With Ziplyftโ„ข
NCT07144761Blepharoplasty
Osheru Inc.
Not applicable
200
Florida, Minnesota, Pennsylvania, South Dakota, Wisconsin
2025-08
Not yet open
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47)
NCT06948019HSP, Hereditary Spastic Paraplegia, Hereditary Spastic Paraparesis, Hereditary Spastic Paraplegia Type 50
BlackfinBio Ltd
Phase 1/2
5
Massachusetts
2025-08
Recruiting
64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
NCT06298916Metastatic Sarcoma, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
Lantheus Medical Imaging
Phase 1/2
26
California, Michigan, Ohio
2025-08
Active, closed
A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
NCT07029711Severe Alopecia Areata
Pfizer
Phase 3
208
California, Colorado, District of Columbia, Florida, Illinois, Indiana, Maryland, Michigan
2025-07-31
Active, closed
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
NCT07044297Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC
Phase 3
4,390
Alabama, California, District of Columbia, Florida, Georgia, Illinois, Louisiana, Mississippi
2025-07-31
Recruiting
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
NCT07073547Multiple Myeloma
AstraZeneca
Phase 1
40
Arizona, California, Colorado, Florida, Georgia, Iowa, Minnesota, Missouri
2025-07-31
Recruiting
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
NCT07096193Chronic Hepatitis Delta
Gilead Sciences
Phase 1/2
200
California, Kentucky, Maryland, New York
2025-07-31
By invitation
A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
NCT06885424Solid Tumor Cancer, Solid Tumor, Unspecified, Adult, Colorectal Carcinoma, Colorectal Carcinoma (CRC)
A2 Biotherapeutics Inc.
Observational
400
Arizona, Minnesota, New York
2025-07-31
Recruiting
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
NCT07094113KRAS Altered Advanced or Metastatic Solid Tumors
Amgen
Phase 1
434
California, Georgia, Massachusetts, Missouri, North Carolina, Pennsylvania, Tennessee, Texas
2025-07-31
By invitation
Pilot Trial Evaluating Patient Experience With the MemorEM for Patients With Neurological Diseases
NCT07049341Alzheimer's Disease, Fronto-temporal Dementia, Parkinson Disease (PD), Cortico Basal Degeneration
NeuroEM Therapeutics, Inc.
Not applicable
100
Florida
2025-07-31
Recruiting
Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study
NCT07113288Obstructive Sleep Apnea (OSA)
Inspire Medical Systems, Inc.
Observational
70
Colorado, Florida, Illinois, Kansas, New York
2025-07-31
Recruiting
WRAP North America
NCT06807099Venous Stenosis, Venous Occlusion
Merit Medical Systems, Inc.
Observational
250
Alabama, Arizona, California, Florida, Kentucky, Rhode Island, South Carolina, Tennessee
2025-07-31
Recruiting
Evaluate the Effects of Citicoline on Mood in Healthy Adults
NCT07089238Healthy
Kirin Holdings Company, Limited
Not applicable
90
Ohio
2025-07-31
Active, closed
Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors
NCT07021066Gastric Adenocarcinoma, Advanced Pancreatic Ductal Adenocarcinoma, Esophageal Adenocarcinoma, Biliary Tract Cancer
SystImmune Inc.
Phase 1
160
Arizona, California, Colorado, Connecticut, Louisiana, Michigan, New Jersey, Tennessee
2025-07-30
Recruiting
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
NCT06990399Macular Edema Secondary to Inflammation
Kodiak Sciences Inc
Phase 3
600
Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana, Maryland
2025-07-30
Recruiting
A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months
NCT07126262Hypochondroplasia
BioMarin Pharmaceutical
Phase 2
60
Arizona, California, District of Columbia, Illinois, Maryland, Minnesota, Missouri, Texas
2025-07-30
Recruiting
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
NCT07002034Adjustment Disorder
Reunion Neuroscience Inc
Phase 2
100
Alabama, Arizona, California, Colorado, Florida, Georgia, Hawaii, Illinois
2025-07-30
Recruiting
DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy
NCT07024693Fuchs Endothelial Corneal Dystrophy, Fuchs
Design Therapeutics, Inc.
Phase 2
28
Indiana, Michigan
2025-07-30
Recruiting
Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)
NCT06780111Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC
Phase 1/2
298
Pennsylvania
2025-07-30
Recruiting
Study of BHV-1400 in IgA Nephropathy
NCT07054684IgA Nephropathy
Biohaven Therapeutics Ltd.
Phase 1
20
Connecticut, Florida, Georgia, Illinois, Indiana, Michigan, Missouri, South Dakota
2025-07-30
Recruiting
SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures
NCT07141329Focal Onset Seizures
Supernus Pharmaceuticals, Inc.
Phase 2
100
Florida
2025-07-30
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies
NCT07024784Gynecologic Cancers, Platinum-Sensitive Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer (PSOC)
AbbVie
Phase 2
377
New Jersey, Ohio, Oklahoma, Oregon, Rhode Island, Tennessee, Texas, Virginia
2025-07-30
Recruiting
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
NCT04433572Peripheral Artery Disease, Critical Limb Ischemia
Mercator MedSystems, Inc.
Phase 3
250
Louisiana, Texas
2025-07-30
Recruiting
A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
NCT07144137Geographic Atrophy Secondary to Age-related Macular Degeneration
Complement Therapeutics
Observational
75
California, Illinois, Indiana, Nevada, North Carolina, Pennsylvania, Texas, Wisconsin
2025-07-30
Active, closed
A Consumer Health Study Evaluating the Impact of Pivit on Weight Loss and Appetite in Overweight Individuals
NCT07245914Obesity &Amp;Amp;Amp; Overweight, Obesity (Body Mass Index &Amp;Amp;Amp;Amp;gt;30 kg/m2)
Olfactive Biosolutions, Inc.
Observational
125
California
2025-07-30
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=30

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