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Compound · clinical trials

Nirmatrelvir/ritonavir clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our Canada, Ireland, India, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Czechia, Portugal, Japan, Australia, Israel, Norway and Brazil registers that name Nirmatrelvir/ritonavir as an intervention. Synced 28 Sep 2026
4Current trials
3Recruiting now
4Lead sponsors
17Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Nirmatrelvir/ritonavir is named as an intervention in 4 current clinical trials in our Canada, Ireland, India, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Czechia, Portugal, Japan, Australia, Israel, Norway and Brazil registers. 3 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is UMC Utrecht (1). The most-studied condition is COVID-19.

Nirmatrelvir/ritonavir also has an approved-drug profile on this site (FDA label data): Paxlovid (Nirmatrelvir/ritonavir) →

Trials by status

  • Recruiting375%
  • Active, closed125%

Trials by phase

  • Phase 3250%
  • Phase 4125%
  • Phase 2125%
01

Clinical trials of Nirmatrelvir/ritonavir

4 trials
StudyPhaseStatusLead sponsorRegisters
Antiviral Strategies in the Prevention of Long-term Cardiovascular Outcomes Following COVID-19: The paxloviD/Remdesivir Effectiveness For the prEvention of loNg coviD Clinical Trial
NCT06792214 · ClinicalTrials.gov ↗ · SARS CoV-2 Post-Acute Sequelae
Phase 4 Recruiting Mount Sinai Hospital, Canada Canada
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
NCT02735707 · ClinicalTrials.gov ↗ · Community-acquired Pneumonia, Influenza, COVID-19
Phase 3 Recruiting UMC Utrecht Ireland, India, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Czechia, Portugal, Canada, Japan, Australia, Israel
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)
NCT05041907 · ClinicalTrials.gov ↗ · COVID-19
Phase 2 Recruiting University of Oxford Brazil
PAxlovid loNg cOvid-19 pRevention triAl With recruitMent In the Community in Norway
NCT05852873 · ClinicalTrials.gov ↗ · Post COVID-19 Condition, Unspecified, SARS-CoV2 Infection, COVID-19
Phase 3 Active, closed Haukeland University Hospital Norway

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Nirmatrelvir/ritonavir

5 conditions
COVID-192Community-acquired Pneumonia, Influenza, COVID-191Post COVID-19 Condition, Unspecified1SARS-CoV2 Infection1SARS CoV-2 Post-Acute Sequelae1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
UMC Utrecht1
Haukeland University Hospital1
Mount Sinai Hospital, Canada1
University of Oxford1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Canada22
Clinical trials in Ireland11
Clinical trials in India11
Clinical trials in Germany11
Clinical trials in France11
Clinical trials in Spain11
Clinical trials in Italy11
Clinical trials in Netherlands11
Clinical trials in Belgium11
Clinical trials in Switzerland11
Clinical trials in Czechia11
Clinical trials in Portugal11
Clinical trials in Japan11
Clinical trials in Australia11
Clinical trials in Israel11
Clinical trials in Norway10
Clinical trials in Brazil11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Nirmatrelvir/ritonavir trials

How many clinical trials are testing Nirmatrelvir/ritonavir?

4 current trials in our Canada, Ireland, India, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Czechia, Portugal, Japan, Australia, Israel, Norway and Brazil registers name Nirmatrelvir/ritonavir as a drug or biological intervention, as of the registry sync on 28 September 2026. Completed and withdrawn studies are not counted.

Are Nirmatrelvir/ritonavir trials recruiting patients?

Yes. 3 of the 4 trials are recruiting: 2 with sites in Canada, 1 with sites in Ireland, 1 with sites in India, 1 with sites in Germany, 1 with sites in France, 1 with sites in Spain, 1 with sites in Italy, 1 with sites in Netherlands, 1 with sites in Belgium, 1 with sites in Switzerland, 1 with sites in Czechia, 1 with sites in Portugal, 1 with sites in Japan, 1 with sites in Australia, 1 with sites in Israel and 1 with sites in Brazil. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Nirmatrelvir/ritonavir clinical trials?

UMC Utrecht (1), Haukeland University Hospital (1), Mount Sinai Hospital, Canada (1) and University of Oxford (1). The number in brackets is how many trials each organisation leads.

Are there Nirmatrelvir/ritonavir clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Nirmatrelvir/ritonavir works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Nirmatrelvir/ritonavir works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Nirmatrelvir/ritonavir (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 28 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.