Neuropathic Characteristics of Subacromial Pain Syndrome

NCT07057128 · tracked via the Priya Life Science Turkey tracker

Sponsor

Izmir City Hospital

Phase

Observational

Started

2025-09-15

Last updated

2026-04-14

Condition(s) studied

Neuropathic PainCentral SensitizationSubacromial Pain Syndrome

Study summary

This single-center observational study aims to investigate neuropathic pain descriptors and their relationship with central sensitization in patients diagnosed with subacromial pain syndrome (SAPS) who have had shoulder pain for at least 3 months. A total of 82 participants aged 19 years or older will be recruited from the Physical Medicine and Rehabilitation outpatient clinic of Izmir City Hospital. After obtaining informed consent, participants will complete validated questionnaires assessing pain severity (VAS), neuropathic pain characteristics (painDETECT), central sensitization (Central Sensitization Inventory), and shoulder function (SPADI). Range of motion will be measured using a goniometer. No imaging or invasive procedures will be performed. Using the central sensitization scale and pain detect, the presence or absence of the 7 pain descriptors will be investigated in patients with subacromial pain syndrome with or without central sensitization and neuropathic pain pattern and it will be investigated whether the contribution of hyperalgesia, one of these pain descriptors, to neuropathic pain and central sensitization in patients with subacromial pain syndrome is greater than the contribution of other pain descriptors.The results of this study are expected to provide insight into pain mechanisms and guide clinical management in patients with SAPS.

Eligibility

Sex

ALL

Min age

19 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. Clinical diagnosis of subacromial pain syndrome (SAPS) 2. Age ≥ 19 years 3. Shoulder pain lasting for at least 3 months 4. Shoulder pain intensity rated as 3 or higher on the Visual Analog Scale (VAS) in the past week 5. Positive findings on the following clinical tests: Hawkins-Kennedy test Painful arc test Infraspinatus muscle strength test Exclusion Criteria: 1. History of inflammatory disease involving the shoulder joint 2. History of neurological disorders 3. History of prior shoulder surgery 4. Positive drop arm test 5. Loss of passive range of motion in the shoulder joint 6. Presence of muscle strength loss 7. Structurally confirmed shoulder pathology based on imaging studies 8. Full-thickness tear of the rotator cuff muscles 9. Presence of neurodeficit in the upper extremity 10. Diagnosis of cancer or active infection 11. Use of medications for neuropathic pain within the past 3 months for any reason

Primary outcome measure(s)

Hyperalgesia — At baseline (single assessment)
Hyperalgesia is defined as an exaggerated pain response to a painful stimulus that is disproportionate to the intensity of the stimulus. It is one of the pain descriptors assessed in the painDETECT questionnaire, which evaluates neuropathic pain features.It is one of the 7 questions in the painDETECT scale that evaluates neuropathic pain and is scored on a 6-point Likert scale and receives a score between 0-5.

Trial sites (1)

Facility	City	Region	Status
İzmir City Hospital	Izmir	İzmir	Recruiting

More Izmir City Hospital trials in Turkey

Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled Trial Starting soon

Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis Recruiting

Preoperative Residual Gastric Volume Active, not recruiting

Live Parent-Child Video Interaction and Cartoon Watching for Emergence Agitation in Children Recruiting

Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement Recruiting

Other trials for the same condition

Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia Recruiting

Impact of GON PRF on Central Sensitization in Migraine Patients Active, not recruiting

Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees Recruiting

Central Sensitization and Ultrasound in Lateral Epicondylitis Recruiting

Comparison of Treatment Alternatives for Myofascial Pain Causing Central Sensitization Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07057128 on ClinicalTrials.gov ↗ ← All trials in Turkey