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Trackers› Clinical trials› León
Clinical trial register · Spain

Clinical Trials in León, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Spain and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5885 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:52 UTC
5885
Studies in scope
all four open statuses
3103
Recruiting now
open to new participants
1139
Lead sponsors
across recruiting studies
Top sites
Barcelona 3233 Madrid 3015 Valencia 1201 Seville 1055 Málaga 741
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Recruitment status
Phase
Lead sponsor
Fundación EPIC6 Eli Lilly and Company6 AbbVie5 AstraZeneca3 MedSIR3
Site location
Barcelona3233 Madrid3015 Valencia1201 Seville1055 Málaga741
All 455 locations
Target enrolment
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Trials with a site in León

69 of 5885 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Spain
Start
Not yet open
Study to Evaluate the Safety and Preliminary Efficacy of CD19 CAR-T Cell Therapy (TranspoCART19) in Patients With Refractory Lupus Nephritis
NCT07799116Lupus Nephritis, Lupus Nephritis (LN)
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Phase 1/2
10
Badalona, Santiago de Compostela, Pamplona, León, Madrid, Murcia, Salamanca, Seville
2026-09
Active, closed
Is Hypoxemia Driving Outcome in Acute Hypoxemic Respiratory Failure? (HOMELAND Study)
NCT07708506Acute Hypoxemic Respiratory Failure
Jesus Villar
Observational
1,241
Barakaldo, Albacete, Barcelona, León, Madrid, Murcia, Valencia, Valladolid
2026-07-13
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
NCT07667803Weight Management
DrugElecoglipron
AstraZeneca
Phase 3
4,500
A Coruña, Almería, Badalona, Barcelona, León, Madrid, Santander, Santiago de Compostela
2026-06-29
Recruiting
A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer
NCT07401381Hormone Receptor Positive Early Breast Cancer
Rovi Pharmaceuticals Laboratories
Phase 1
120
Alcorcón, Barcelona, Granada, León, Lleida, Manresa, Málaga, Murcia
2026-06-08
Recruiting
Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution
NCT07634952Heat Strain
University of Cyprus
Not applicable
102
León
2026-05-01
Active, closed
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
NCT07503210Obesity
DrugNNC0487-0111
Novo Nordisk A/S
Phase 3
606
Almería, Barcelona, León, Madrid, Málaga, Pozuelo de Alarcón, Seville
2026-04-21
Recruiting
Efficacy and Safety of Camizestrant Plus Ribociclib in Patients With Breast Cancer
NCT07195227Hormon Receptor Positive Breast Cancer, Breast Cancer
DrugsCamizestrant·Ribociclib
MedSIR
Phase 2
150
Alicante, Barcelona, Girona, Granada, Jerez de la Frontera, León, Madrid, Málaga
2026-03-24
Recruiting
Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary Syndrome
NCT07476859Acute Coronary Syndromes (ACS), Iron Deficiencies, Elderly (People Aged 65 or More)
DrugsFerinject·Ferric Carboxymaltose
Fundación para la Investigación del Hospital Clínico de Valencia
Phase 4
538
El Palmar, Vigo, Badajoz, Barcelona, Granada, León, Madrid, Pamplona
2026-03-05
Recruiting
LONG NAGOMI™ PMCF STUDY
NCT07399002Coronary Artery Disease, Ischemic Heart Disease
Fundación EPIC
Observational
1,039
Cabueñes, Ciudad Real, Elche, Huelva, León, Málaga, Pamplona, Santander
2026-02-27
Recruiting
A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
NCT07095452Multiple Myeloma
DrugsEtentamig·Daratumumab·Lenalidomide·Dexamethasone
AbbVie
Phase 2/3
680
Santiago de Compostela, Badalona, Santander, Las Palmas de Gran Canaria, Pamplona, Barcelona, León, Madrid
2026-01-08
Recruiting
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
NCT07286578Cardiovascular Diseases, Myocardial Ischemia, Heart Diseases, Arteriosclerosis
Fundación EPIC
Not applicable
700
Barcelona, León, Madrid
2025-12-22
Recruiting
WATCHMAN FLX Pro European Registry
NCT07262255Non-valvular Atrial Fibrillation (AF), Left Atrial Appendage Closure
Boston Scientific Corporation
Observational
1,000
León, Pamplona, Pontevedra, Salamanca
2025-12-17
Recruiting
Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry
NCT07256249Cardiovascular Diseases
Fundación EPIC
Observational
960
Vilagarcía de Arousa, Badalona, Barcelona, León, San Cristóbal de La Laguna, Santander, Santiago de Compostela, Seville
2025-12-11
Recruiting
Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis
NCT07505355Multiple Sclerosis, Healthy Controls Group - Age and Sex-matched
Hasselt University
Observational
100
León
2025-11-10
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Ribociclib·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Alicante, Barcelona, Granada, León, Lleida, Madrid, Murcia, Seville
2025-11-03
Recruiting
Saccharomyces Boulardii CNCM I-745 in Irritable Bowel Syndrome
NCT07168434IBS (Irritable Bowel Syndrome), IBS-D (Diarrhea-predominant), IBS, Mixed Symptoms
DrugSaccharomyces boulardii
Biocodex
Phase 3
406
Barcelona, León, Madrid, Marbella, Málaga, Oviedo
2025-10-22
Recruiting
Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque Psoriasis
NCT07039110Plaque Psoriasis
AbbVie
Observational
700
Málaga, León, Cartagena, El Palmar, Murcia, Pontevedra, Toledo
2025-09-09
Recruiting
Repotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain Metastasis
NCT06315010NSCLC, Brain Metastases, ROS1 Gene Rearrangement
DrugRepotrectinib
MedSIR
Phase 2
20
Elche, Barcelona, Girona, Madrid, Reus, Alicante, Barakaldo, León
2025-06-27
Active, closed
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
NCT06948435Hypertension, Overweight or Obesity
DrugOrforglipron
Eli Lilly and Company
Phase 3
487
A Coruña, Barcelona, Centelles, León, Seville
2025-04-30
Active, closed
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
NCT06952530Hypertension
DrugOrforglipron
Eli Lilly and Company
Phase 3
487
A Coruña, Barcelona, Centelles, León, Seville
2025-04-30
Active, closed
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
NCT06948422Hypertension
DrugOrforglipron
Eli Lilly and Company
Phase 3
974
A Coruña, Barcelona, Centelles, León, Seville
2025-04-30
Recruiting
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
NCT06712355Extensive-stage Small-cell Lung Cancer
DrugsPumitamig·Etoposide·Atezolizumab·Carboplatin
BioNTech SE
Phase 3
621
Badajoz, Barcelona, Castellon, León, Madrid, Málaga, Seville, Torrejón de Ardoz
2025-02-03
Recruiting
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
NCT06712316Non-small Cell Lung Cancer
DrugsPumitamig·Pemetrexed·Paclitaxel·Carboplatin
BioNTech SE
Phase 2/3
1,580
A Coruña, Badajoz, Badalona, Barcelona, Castellon, Las Palmas de Gran Canaria, León, Lleida
2025-01-07
Recruiting
Pembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage TNBC
NCT06078384Triple-negative Breast Cancer
DrugsTaxol·Keytruda·Paclitaxel·Pembrolizumab
UNICANCER
Phase 2
354
Alicante, Badalona, Barcelona, El Palmar, Granada, L'Hospitalet de Llobregat, León, Lleida
2024-12-27
Recruiting
DEBSCAN-IVL. Drug Eluting Balloon or Drug Eluting Stent to Treat CAlcified Nodules After IntraVascular Lithotripsy.
NCT06657833Coronary Artery Disease
Fundación EPIC
Not applicable
128
Barcelona, Fuencarral-El Pardo, Galdakao, León, Madrid, Moncloa-Aravaca, Pamplona, Valencia
2024-12-17
Active, closed
A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)
NCT06537414Chronic Hepatitis B Virus Infection, Hepatitis B
DrugBepirovirsen
GlaxoSmithKline
Phase 2
283
Barcelona, León, Madrid, Salamanca, Santander, Valencia
2024-11-11
Recruiting
DRUG RELEASING BALL vs. PHARMACOACTIVE STENT IN LARGE VESSELS: MORPHOLOGICAL ANALYSIS AND FUNCTION VASOMOTOR (DEBORA STUDY) IN LARGE VESSELS: MORPHOLOGICAL ANALYSIS AND FUNCTION VASOMOTOR (DEBORA STUDY)
NCT06448637Coronary Artery Disease
Fundación EPIC
Not applicable
94
Barcelona, Gijón, Huelva, León, Lugo, Oviedo, Pontevedra, Tarragona
2024-10-23
Active, closed
Randomized Double-Blind Trial on Safety and Efficacy of Nanordica Advanced Antibacterial Wound Dressing for Diabetic Foot Ulcer
NCT06667752Diabetic Foot Ulcer, Diabetic Foot Infection
Nanordica Medical OU
Not applicable
136
Arcos de la Frontera, Cadiz, Jerez de la Frontera, León, Madrid, San Sebastián
2024-10-17
Recruiting
Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer
NCT06446882HER2-positive Breast Cancer, Early-stage Breast Cancer
Fundacio Clinic Barcelona
Not applicable
304
L'Hospitalet de Llobregat, Granada, Santiago de Compostela, León, Madrid, Murcia, Reus, Bilbao
2024-10-11
Recruiting
A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease
NCT06613698Liver Diseases, Alcoholic
DrugGSK4532990
GlaxoSmithKline
Phase 2
393
Barcelona, León, Madrid, Santander, Seville, Valencia, Valladolid, Vigo
2024-09-27
Active, closed
RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms
NCT06243458Low Risk Myelodysplastic Syndromes
DrugRVU120
GCP-Service International West GmbH
Phase 2
41
Barcelona, León, Madrid, Pamplona, Salamanca, Valencia
2024-09-10
Active, closed
A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
NCT06440967Hot Flashes
DrugsFezolinetant·Tamoxifen
Astellas Pharma Global Development, Inc.
Phase 3
982
Barcelona, Elche, Girona, Granada, Jaén, León, Madrid, Majadahonda
2024-07-31
Active, closed
PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
NCT06172127HER2-positive Breast Cancer
DrugsPhesgo·Trastuzumab deruxtecan
MedSIR
Phase 2
165
Seville, Alicante, Barcelona, Bilbao, Castellon, Córdoba, Granada, León
2024-07-22
Active, closed
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06158841Multiple Myeloma
DrugsElotuzumab·Etentamig·Carfilzomib·Selinexor
AbbVie
Phase 3
421
Badalona, Ourense, León, Madrid, Salamanca, Valencia
2024-05-19
Recruiting
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
NCT06119581Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
DrugsOlomorasib·Pemetrexed·Cisplatin·Carboplatin
Eli Lilly and Company
Phase 3
1,264
A Coruña, Badajoz, Barakaldo, Barcelona, Hospitalet, Jerez de la Frontera, Las Palmas de Gran Canaria, León
2023-12-21
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NCT05963698Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
Hamilton Health Sciences Corporation
Not applicable
4,000
Vigo, Alicante, Barcelona, Huelva, León, Madrid, Valladolid
2023-11-30
Active, closed
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT06016738Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Exemestane·Anastrozole·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
510
Badajoz, Badalona, Manresa, Girona, León, Lleida, Madrid, Pamplona
2023-11-16
Active, closed
A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain
NCT06125795Chronic Lymphocytic Leukemia
AbbVie
Observational
146
Vitoria-Gasteiz, Manresa, Terrassa, Jerez de la Frontera, Laredo, Santander, Las Palmas de Gran Canaria, León
2023-11-06
Active, closed
Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy
NCT05952206Coronary Artery Disease
Drug12-month DAPT
iVascular S.L.U.
Phase 3
2,312
A Coruña, Almería, Barcelona, Cáceres, Huelva, Jerez de la Frontera, Las Palmas de Gran Canaria, León
2023-10-13
Recruiting
A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma
NCT05730036Relapsed Refractory Multiple Myeloma (RRMM)
DrugsElotuzumab·Linvoseltamab·Pomalidomide·Dexamethasone
Regeneron Pharmaceuticals
Phase 3
410
Santiago de Compostela, Vitoria-Gasteiz, Palma, Palma Mallorca, Badalona, Terrassa, Santander, León
2023-09-18
Recruiting
The ReTAVI Prospective Observational Registry
NCT05601453Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
Institut für Pharmakologie und Präventive Medizin
Observational
250
Barcelona, León, Madrid, Oviedo, Vigo
2023-09-05
Recruiting
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT05797831Endometrial Cancer
DrugNavtemadlin
Kartos Therapeutics, Inc.
Phase 2/3
268
A Coruña, Barcelona, Galdakao, Jaén, Jerez de la Frontera, Las Palmas, León, Santiago de Compostela
2023-07-17
Active, closed
Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients
NCT05705973Cardiovascular Disease, Coronary Artery Occlusion, Ischemic Heart Disease
Terumo Europe N.V.
Observational
3,000
Barcelona, Huelva, León, Salamanca, Seville
2023-04-25
Active, closed
A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma
NCT05572515Relapsed or Refractory Multiple Myeloma
DrugsTeclistamab·Carfilzomib·Pomalidomide·Bortezomib
Janssen Research & Development, LLC
Phase 3
614
Badalona, Jerez de la Frontera, L'Hospitalet de Llobregat, León, Madrid, Murcia, Oviedo, Palma de Mallorca
2023-03-29
Recruiting
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
NCT05712200Atrial Fibrillation (AF)
DrugAbelacimab
Anthos Therapeutics, Inc.
Phase 3
2,500
A Coruña, Almería, Barcelona, Cabra, Granada, Jaén, León, Madrid
2022-12-27
Active, closed
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
NCT05581303Atherosclerotic Cardiovascular Disease
DrugOlpasiran
Amgen
Phase 3
7,297
Córdoba, Málaga, Seville, Zaragoza, León, Badalona, Barcelona, L'Hospitalet de Llobregat
2022-12-14
Active, closed
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796Obesity
DrugsCagrilintide·Semaglutide
Novo Nordisk A/S
Phase 3
3,400
Pamplona, Barcelona, Castilleja de la Cuesta, León, Madrid, Seville
2022-11-01
Active, closed
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
NCT05455320Multiple Myeloma
DrugsTalquetamab·Pomalidomide·Daratumumab·Dexamethasone
Janssen Research & Development, LLC
Phase 3
864
Badalona, Barcelona, El Palmar, Jerez de la Frontera, León, Madrid, Málaga, Pamplona
2022-10-13
Active, closed
A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
NCT05556512Obesity, Overweight
DrugTirzepatide
Eli Lilly and Company
Phase 3
15,374
A Coruña, Almería, Alzira, Barcelona, Bilbao, Ferrol, Granada, León
2022-10-11
Recruiting
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT05519085Relapsed or Refractory Multiple Myeloma
DrugsMezigdomide·Pomalidomide·Bortezomib·Dexamethasone
Celgene
Phase 3
810
Palma, Barcelona, Murcia, Marbella, Cáceres, León, Madrid
2022-09-20
Recruiting
Spanish Academy of Dermatology and Venereology (AEDV) Melanoma Registry
NCT05673681Melanoma
Fundación Academia Española de Dermatología
Observational
7,000
Badalona, A Coruña, Barcelona, Córdoba, Las Palmas, León, Madrid, Oviedo
2022-06-01
Active, closed
Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer
NCT05296746Breast Cancer Stage II
DrugRibociclib
SOLTI Breast Cancer Research Group
Phase 2
1,100
Palma de Mallorca, Badalona, L'Hospitalet de Llobregat, Barcelona, Granada, León, Madrid, Salamanca
2022-05-03
Active, closed
Endometrial Cancer Patientes MMR Deficient Comparing Chemotherapy vs Dostarlimab in First Line
NCT05201547Endometrial Cancer
DrugsCarboplatin/Paclitaxel·Dostarlimab
ARCAGY/ GINECO GROUP
Phase 3
260
Elche, Badalona, Córdoba, León, Palma, Palma de Mallorca, Santiago de Compostela, Valencia
2022-04-15
Active, closed
Parenteral Antiplatelet Agents in Real-world Spanish PCI Patients
NCT05193019Ischemic Heart Disease, Acute Coronary Syndrome
Fundación EPIC
Observational
717
L'Hospitalet de Llobregat, Barakaldo, Galdakao, Gijón, León, Madrid, Pamplona, Salamanca
2022-03-14
Active, closed
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
DrugsZanubrutinib·Obinutuzumab·Lenalidomide·Rituximab
BeOne Medicines
Phase 3
799
Badalona, Burgos, Cadiz, Granada, L'Hospitalet de Llobregat, León, Madrid, Majadahonda
2022-03-10
Active, closed
A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)
NCT04819100Carcinoma, Non-Small-Cell Lung
DrugSelpercatinib
Eli Lilly and Company
Phase 3
152
Santiago de Compostela, Cadiz, Córdoba, Badalona, Barcelona, L'Hospitalet Del Llobregat, Mataró, León
2021-12-20
Active, closed
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
NCT04954859Hepatitis B
DrugBepirovirsen
GlaxoSmithKline
Phase 2
360
HebrOn, León, Madrid, Santander, Valencia, Vigo
2021-12-14
Recruiting
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma
NCT05160584Relapsed/Refractory Multiple Myeloma
Janssen Pharmaceutica N.V., Belgium
Observational
300
Barcelona, Gijón, Granada, Jerez de la Frontera, León, Madrid, Palma, Pamplona
2021-11-18
Active, closed
Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases
NCT05012254Non Small Cell Lung Cancer, Brain Metastases, Adult, Lung Cancer
DrugsYervoy·Paraplatin·Taxol·Opdivo
Fundación GECP
Phase 2
71
Badalona, Barcelona, L'Hospitalet de Llobregat, Castellon, Las Palmas de Gran Canaria, Jaén, A Coruña, León
2021-11-18
Active, closed
A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
NCT04765059Non-small Cell Lung Cancer
DrugCarboplatin
AstraZeneca
Phase 3
98
Alicante, Barcelona, Córdoba, León, Madrid, Málaga, Murcia, Oviedo
2021-09-12
Active, closed
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728NASH - Nonalcoholic Steatohepatitis
Inventiva Pharma
Phase 3
1,000
Almería, Badalona, Palma de Mallorca, Barcelona, Sabadell, León, Madrid, Majadahonda
2021-08-19
Recruiting
Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery
NCT04926597Malnutrition
Philipp Schuetz
Not applicable
1,200
Barcelona, Getafe, León, Madrid, Málaga, Valladolid
2021-08-05
By invitation
Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting
NCT04451044Coronary Artery Disease, Ischemic Heart Disease
Philips Clinical & Medical Affairs Global
Not applicable
3,212
Córdoba, León, Madrid, Santander
2021-06-17
Active, closed
Study With Atezolizumab in Combination With Trastuzumab and Vinorelbine in HER2-positive Advanced/Metastatic Breast Cancer
NCT04759248Breast Cancer
DrugsVinorelbine·Trastuzumab·Atezolizumab
SOLTI Breast Cancer Research Group
Phase 2
55
Granada, Barcelona, L'Hospitalet de Llobregat, Santa Cruz de Tenerife, A Coruña, Alicante, Cáceres, León
2021-03-15
Not yet open
Prospective i-FactorTM Analysis Fusion Rate and Quality of Life
NCT04610021Spinal Deformity, Bone Graft, Fusion Rate, Quality of Life
Complejo Asistencial Universitario de León Urgencias
Not applicable
128
León
2021-03
Active, closed
CHAMPION-AF Clinical Trial
NCT04394546Atrial Fibrillation, Stroke, Bleeding
DrugNon-Vitamin K Anticoagulant
Boston Scientific Corporation
Not applicable
3,000
Vigo, León, Salamanca
2020-10-15
Active, closed
A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma.
NCT03539744Multiple Myeloma
DrugsPomalidomide·Venetoclax·Dexamethasone
AbbVie
Phase 3
265
Palma de Mallorca, Marbella, Ourense, San Cristóbal de La Laguna, Barcelona, Girona, León, Madrid
2018-10-22
Active, closed
Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)
NCT02453282Non-Small-Cell Lung Carcinoma NSCLC
DrugsTremelimumab·Durvalumab·Pemetrexed·Gemcitabine
AstraZeneca
Phase 3
1,118
A Coruña, Alicante, Barcelona, Girona, Jaén, León, Madrid, Majadahonda
2015-07-21
Recruiting
Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)
NCT06911099Atrial Functional Mitral Regurgitation, Mitral Insufficiency
University Hospital of Cologne
Observational
1,000
Barcelona, Córdoba, León, Oviedo, Vigo
2010-01-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Spanish investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 28 September 2026. https://priyalifescience.com/clinical-trials-spain/city/le-n

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Spain and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,885 studies in total at the last sync on 26 Sep 2026, 19:52 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 69 of those studies with a site in León.

How many clinical trials are recruiting in León?

33 of the 69 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:52 UTC sync. A further 2 have not yet opened recruitment, 33 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (León), 69 studies
PhaseStudiesRecruitingShare
Phase 328840.6%
Observational13918.8%
Not applicable11715.9%
Phase 211415.9%
Phase 2/3334.3%
Phase 1111.4%
Phase 1/2101.4%
Phase 4111.4%

Most active sponsors

Lead sponsors with the most studies (León)
Lead sponsorStudiesRecruiting
Eli Lilly and Company61
Fundación EPIC65
AbbVie52
AstraZeneca31
GlaxoSmithKline31
MedSIR32
BioNTech SE22
Boston Scientific Corporation21
Janssen Research & Development, LLC20
Novo Nordisk A/S20
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.