caudal block using dexmedetomidine with bupivacainecaudal block with bupivacaine
caudal block using dexmedetomidine with bupivacaine: Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 µg/kg of dexmedetomidine (diluted in 1 mL of normal saline).
caudal block with bupivacaine: Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 mL of normal saline
Study summary
This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.
Eligibility
Sex
ALL
Min age
2 Years
Max age
7 Years
Healthy volunteers
No
inclusion criteria:
* ASA (American Society of Anesthesiologists) physical status I or II.
* Legal guardian provides written informed consent. Exclusion Criteria
* Refusal of participation by the legal guardian.
* Known allergy or hypersensitivity to local anesthetics or dexmedetomidine.
* Coagulation disorder or receiving anticoagulant therapy.
* Active infection at or near the injection site.
* Significant anatomical abnormalities of the lumbosacral spine.
* Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions.
* Anticipated surgery time of more than 2.5 hours.
* Patients with severe asthma or active wheezing.
Primary outcome measure(s)
Time to First Rescue Analgesia: — Up to 24 hours post-caudal block Defined as the time interval in minutes from the performance of the caudal block until the first administration of rescue analgesia (ibuprofen), which is prompted by a FLACC pain score of ≥ 4.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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