Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics

NCT07618650 · tracked via the Priya Life Science Egypt tracker

Sponsor

Tanta University

Phase

Not applicable

Started

2025-06-30

Last updated

2026-06-01

Condition(s) studied

Transversalis Fascia Plane BlockQuadratus Lumborum BlockAppendectomy

Investigational drug(s) / intervention(s)

Transversalis Fascia Plane Block groupQuadratus Lumborum Plane Block group

Transversalis Fascia Plane Block group: 35 Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.

Quadratus Lumborum Plane Block group: 35 patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision

Study summary

This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.

Primary outcomes:

• Proportion of patients needing rescue analgesia within the first 24 postoperative hours.

Secondary outcomes:

* Visual Analogue Scale pain intensity measurements.
* Intraoperative Heart rate and mean arterial blood pressure will be recorded.
* Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
* Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
* Parents' satisfaction score.

Eligibility

Sex

ALL

Min age

7 Years

Max age

12 Years

Healthy volunteers

Inclusion Criteria: * 70 patients aged between 7 and 12 years of both sexes undergoing appendectomy, American Society of Anesthesiologists (ASA) physical status of I or II Exclusion Criteria: * Refusal of parents to participate * Patients with peritonitis * History of allergy to bupivacaine and other amide local anesthetics * Infection at the site of block needle entry * Bleeding diathesis * Neurological disorders * American Society of Anesthesiologists ≥ III

Primary outcome measure(s)

Proportion of patients needing rescue analgesia — within the first 24 postoperative hours.

Trial sites (1)

Facility	City	Region	Status
Tanta University	Tanta	Egypt

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07618650 on ClinicalTrials.gov ↗ ← All trials in Egypt