Transversalis fascia plane block: Patients will receive spinal anesthesia (using 2.5 mL of hyperbaric bupivacaine 0.5%) with bilateral transversalis fascia plane (TFP) block (using 20 mL of bupivacaine 0.25%) at the end of surgery.
Intrathecal dexmedetomidine: Patients will receive spinal anesthesia (using 2.5 mL of hyperbaric bupivacaine 0.5%) + (5 µg intrathecal dexmedetomidine diluted in 0.5ml saline) with a sham block at the end of surgery.
Study summary
This study aims to compare the analgesic efficacy of the transversalis fascia plane (TFP) block and intrathecal dexmedetomidine in patients undergoing cesarean section (CS).
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
40 Years
Healthy volunteers
No
Inclusion Criteria:
* Age from 18 to 40 years.
* American Society of Anesthesiology (ASA) physical status II.
* Women undergoing cesarean section under spinal anesthesia.
Exclusion Criteria:
* Contraindication to spinal anesthesia.
* Women with body mass index \>40 kg/m2.
* Pregnancy-induced hypertension
* Local infection at the site of injection.
* Known cardiovascular disease
* Coagulation abnormality.
* History of chronic pain.
* Abuse of drugs or alcohol.
* History of allergies to any study medications.
* Seizure disorders.
* Any pregnancy complications requiring conversion to general anesthesia.
Primary outcome measure(s)
Degree of pain — 24 hours postoperatively Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS will be assessed at post-anesthesia care unit (PACU), 2, 4, 6, 8, 12, 18 and 24 h postoperatively.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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