Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate

NCT05821972 · tracked via the Priya Life Science Egypt tracker

Sponsor

Assiut University

Phase

Phase 4

Started

2024-04-10

Last updated

2025-10-03

Condition(s) studied

SedationEmergence Delirium

Investigational drug(s) / intervention(s)

Nebulization of dexmedetomidine and ketamineNebulization of dexmedetomidine

Nebulization of dexmedetomidine and ketamine: Pre-operative nebulization of dexmedetomidine and ketamine

Nebulization of dexmedetomidine: Pre-operative nebulization of dexmedetomidine

Study summary

To compare the efficacy of the pre-operative nebulization of a combination of dexmedetomidine and ketamine versus nebulization of dexmedetomidine alone for sedation and prevention of emergence delirium in children undergoing cleft palate repair surgeries.

Eligibility

Sex

ALL

Min age

12 Months

Max age

48 Months

Healthy volunteers

Inclusion Criteria: * Patients with American Society of Anesthesiologists (ASA) physical status I \& II who will be scheduled for cleft palate repair surgeries Exclusion Criteria: * Parent refusal * Allergy to the study drugs * Suspected difficult airway * Patients with endocrine, renal, hepatic, and cardiac pathology * Psychiatric diseases * Asthmatic patients.

Primary outcome measure(s)

University of Michigan Sedation Scale (UMSS) — Pre-operative
It ranges from 0 = awake, alert to 4 = unarousable

Trial sites (1)

Facility	City	Region	Status
Assiut University	Asyut	Egypt	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05821972 on ClinicalTrials.gov ↗ ← All trials in Egypt