Serum level of Human Talin-1Serum level of Human Cripto-1
Serum level of Human Talin-1: To evaluate the clinical utility of Talin-1 measurement in colorectal cancer patients in comparison with healthy controls.
Serum level of Human Cripto-1: To evaluate the clinical utility of Cripto-1 measurement in colorectal cancer patients in comparison with healthy controls.
Study summary
The goals of this study are
* To evaluate the clinical utility of Talin-1 and Cripto-1 measurement in colorectal cancer patients in comparison with healthy controls.
* To Compare the diagnostic significance of serum Talin-1 and Cripto-1 with traditional serum biomarker CEA
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Age \>18 years Old.
* Patients of both sexes who met the clinical diagnostic criteria of colorectal cancer (change in bowel habit, absolute or recurrent constipation, rectal bleeding, significant weight loss or intestinal obstruction)
* Patients diagnosed with colorectal cancer by imaging and histopathology
Exclusion Criteria:
* Age \<18 years old.
* Patients with past history of chemotherapy or surgical excision of tumor
* Patients with familial adenomatous polyposis
* Patients with hereditary non-polyposis colorectal cancer
* Patients with inflammatory bowel disease
* patients with other types of tumors
Primary outcome measure(s)
Serum Talin-1 measurement in colorectal cancer patients — From enrollment up to one week measuring serum level of talin-1 in colorectal cancer patient to compare its level with healthy control
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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