Prediction of Postoperative Recurrence in Crohn's Disease
NCT07824791 · ClinicalTrials.gov ↗ · Crohn Disease (CD), Postoperative Recurrence and Metastasis
|
Observational |
Recruiting |
2025-07 |
China |
Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Randomized Controlled Trial
NCT07328958 · ClinicalTrials.gov ↗ · Hypotension During Surgery
|
Not applicable |
Recruiting |
2026-01 |
China |
|
Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer
|
Observational |
Recruiting |
2024-10 |
China |
SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC
NCT07549399 · ClinicalTrials.gov ↗ · Rectal Adenocarcinoma, High-Risk Cancer, MSS
|
Phase 3 |
Recruiting |
2026-05 |
China |
A Prospective, Single-Arm Clinical Study of a Dietary Supplement for the Prevention of Acute Radiation-Induced Rectal Injury During Neoadjuvant Chemoradiotherapy for Rectal Cancer
NCT07802002 · ClinicalTrials.gov ↗ · Radiotherapy, Radiation-Induced Complications
|
Not applicable |
Recruiting |
2026-07 |
China |
Fecal Microbiota Transplantation for Radiation-Induced Proctopathy
NCT06776029 · ClinicalTrials.gov ↗ · Radiation Induced Proctitis
|
Phase 2 |
Recruiting |
2025-02 |
China |
Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer
NCT07154173 · ClinicalTrials.gov ↗ · Rectal Neoplasms, Colon Neoplasms, Microbiota
|
Observational |
Recruiting |
2025-01 |
China |
TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal Response
NCT07510191 · ClinicalTrials.gov ↗ · Crohn Disease (CD)
|
Phase 4 |
Recruiting |
2026-03 |
China |
Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer
NCT06364371 · ClinicalTrials.gov ↗ · Predictive Cancer Model, Pathologic Complete Response
|
Observational |
Recruiting |
2024-06 |
China |
|
Study on Repeat Liposomal Bupivacaine for Post-Surgery Pain in Anal Fistula Patients.
|
Not applicable |
Recruiting |
2025-07 |
China |
Multicenter Prospective Observational Study of Cardiotoxicity in Patients Receiving Targeted Cancer Therapies
NCT07058454 · ClinicalTrials.gov ↗ · Cancer;Cardiovascular;Adverse Events, Cancer
|
Observational |
Recruiting |
2025-09 |
China |
Superior HypogastrIc plExus bLock During Laparoscopic Colorectal Cancer Surgery
NCT07579780 · ClinicalTrials.gov ↗ · Colorectal Cancer (Diagnosis), Laparoscopic Surgery, Superior Hypogastric Plexus Block
|
Not applicable |
Recruiting |
2025-12 |
China |
PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN)
NCT06182215 · ClinicalTrials.gov ↗ · Elective Major Abdominal Surgery
|
Observational |
Recruiting |
2023-12 |
China |
Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer
NCT05943444 · ClinicalTrials.gov ↗ · Rectal Neoplasms, Low Anterior Resection Syndrome, Anastomotic Leak
|
Not applicable |
Recruiting |
2023-08 |
China |
Stereotactic Body Radiation Therapy for Unresectable Locally Recurrent Rectal Cancer
NCT07297004 · ClinicalTrials.gov ↗ · Unresectable Locally Recurrent Rectal Cancer
|
Phase 2 |
Recruiting |
2025-01 |
China |
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
NCT06407518 · ClinicalTrials.gov ↗ · Preoperative, Sleep Disturbance, Anxiety
|
Not applicable |
Recruiting |
2024-07 |
China |
Interleukin-23 Monoclonal Antibody for Inflammatory Bowel Disease: Efficacy and Safety
NCT07216014 · ClinicalTrials.gov ↗ · Crohn's Disease and Ulcerative Colitis
|
Phase 4 |
Recruiting |
2025-12 |
China |
Node-Sparing Hypofractionated Radiotherapy Plus Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Randomized, Phase II Trial
NCT07230639 · ClinicalTrials.gov ↗ · Neoadjuvant Therapies, Immune Checkpoint Therapy, Radiotherapy
|
Phase 2 |
Recruiting |
2025-08 |
China |
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy
NCT03587480 · ClinicalTrials.gov ↗ · Rectal Neoplasm Malignant
|
Not applicable |
Recruiting |
2018-12 |
China |
Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC)
NCT06958419 · ClinicalTrials.gov ↗ · Immune Checkpoint Therapy, Radiotherapy, Metastatic Colorectal Cancer (CRC)
|
Phase 2/3 |
Recruiting |
2025-05 |
China |
Efficacy and Safety of Upatinib in the Treatment of Active Anal Fistulas in Crohn's Disease
NCT06902987 · ClinicalTrials.gov ↗ · Crohn's Diseases, Active Anal Fistula, Upadacitinib
|
Phase 1 |
Recruiting |
2024-01 |
China |
|
Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI
|
Observational |
Recruiting |
2022-06 |
China |
|
Node-Sparing Short-Course Radiotherapy (25 Gy/5 Fractions) Combined With Chemoimmunotherapy as Neoadjuvant Treatment for Locally Advanced Esophageal Squamous Cell Carcinoma:A Prospective Single-Arm, Phase II Study
|
Phase 2 |
Recruiting |
2026-09 |
China |
|
Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer
|
Not applicable |
Recruiting |
2021-01 |
China |
Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients
NCT05797467 · ClinicalTrials.gov ↗ · Colorectal Cancer, Chemotherapy Effect
|
Phase 3 |
Recruiting |
2023-04 |
China |
Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis
NCT03748485 · ClinicalTrials.gov ↗ · Colorectal Cancer, Adjuvant Chemotherapy
|
Not applicable |
Recruiting |
2019-04 |
China |
Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)
NCT06958432 · ClinicalTrials.gov ↗ · Rectal Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy
|
Phase 2/3 |
Recruiting |
2025-05 |
China |
|
Real-World Study of IL-23 Inhibitors in Active Crohn's Disease
|
Observational |
Recruiting |
2026-04 |
China |
Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC
NCT06998758 · ClinicalTrials.gov ↗ · Neoadjuvant Chemotherapy, Weight Loss
|
Phase 3 |
Recruiting |
2025-11 |
China |
Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression
NCT07176182 · ClinicalTrials.gov ↗ · Rectal Cancer Patients, Rectal Cancer Stage II, Rectal Cancer Stage III
|
Phase 2 |
Recruiting |
2026-03 |
China |
A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)
NCT07669220 · ClinicalTrials.gov ↗ · Rectal Adenocarcinoma, High-risk Locally Advanced, Short-course Radiotherapy (SCRT)
|
Phase 2 |
Recruiting |
2026-01 |
China |
ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer
NCT05815082 · ClinicalTrials.gov ↗ · Colorectal Cancer, Liver Metastases, Circulating Tumor Cell
|
Phase 3 |
Recruiting |
2023-02 |
China |
A Retrospective Analysis of Robot-Assisted Versus Endoscopic Breast-Conserving Surgery for Breast Cancer
NCT07321145 · ClinicalTrials.gov ↗ · Breast Cancer, Breast Surgery
|
Not applicable |
Recruiting |
2025-06 |
China |
Efficacy and Safety of Vedolizumab Combined With Upadacitinib in Patients With Ulcerative Colitis
NCT06095596 · ClinicalTrials.gov ↗ · Ulcerative Colitis (UC)
|
Not applicable |
Recruiting |
2023-11 |
China |
Perioperative Oxaliplatin With S-1 Combined H. Pylori Eradication in the Management of Locally Advanced Gastric Cancer
NCT06510010 · ClinicalTrials.gov ↗ · Chemotherapy Effect
|
Phase 2 |
Recruiting |
2024-12 |
China |
|
Exclusive Enteral Nutrition Therapy for Active and Complicated Crohn's Disease
|
Observational |
Recruiting |
2020-06 |
China |
Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Moderate-to-Severe Ulcerative Colitis
NCT07442045 · ClinicalTrials.gov ↗ · Ulcerative Colitis (UC)
|
Observational |
Recruiting |
2023-01 |
China |
Dietary Supplements to Treat Radiation-Induced Rectal Injury
NCT06776016 · ClinicalTrials.gov ↗ · Radiotherapy, Radiation Proctitis
|
Phase 2 |
Recruiting |
2025-01 |
China |
SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer(SPARKLE)
NCT06767007 · ClinicalTrials.gov ↗ · Unresectable Locally Recurrent Rectal Cancer
|
Phase 2 |
Recruiting |
2025-01 |
China |
Association Between Preoperative Metformin Exposure and Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia
NCT07244575 · ClinicalTrials.gov ↗ · Postoperative Nausea and Vomiting
|
Observational |
Recruiting |
2025-12 |
China |
Predicting Gastric Cancer Response to Chemo With Multimodal AI Model
NCT06451393 · ClinicalTrials.gov ↗ · Gastric Cancer, Chemotherapy Effect
|
Observational |
Recruiting |
2013-02 |
China |
Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC
NCT06002789 · ClinicalTrials.gov ↗ · Multiple Cancer, Colorectal Cancer
|
Phase 2 |
Recruiting |
2022-05 |
China |
Tubeless NOSES Versus Laparoscopic Radical Resection for Rectosigmoid Cancers
NCT04037956 · ClinicalTrials.gov ↗ · Tubeless NOSES, Traditional Laparoscopic Radical Resection, Rectosigmoid Cancers
|
Not applicable |
Recruiting |
2019-06 |
China |
Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)
NCT06923345 · ClinicalTrials.gov ↗ · Rectal Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy
|
Phase 2 |
Recruiting |
2025-03 |
China |
The Impact of MTM Model on the Efficacy and Safety of Anticoagulant Therapy in Postoperative Colorectal Cancer Patients
NCT06998745 · ClinicalTrials.gov ↗ · Thrombosis, Venous
|
Not applicable |
Recruiting |
2025-05 |
China |
Association Between Clinical Classification and Prognosis in Chronic Radiation Enteropathy
NCT07378631 · ClinicalTrials.gov ↗ · Radiotherapy, Radiation Proctitis, Radiation Enteritis
|
Observational |
Recruiting |
2025-12 |
China |
Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA
NCT05797077 · ClinicalTrials.gov ↗ · Colorectal Cancer, Liver Metastases, Circulating Tumor Cell
|
Phase 3 |
Recruiting |
2023-02 |
China |
Radical Concurrent Chemoradiotherapy With DDP/5-FU and PD-1 Antibody for Non-metastatic Rectal Squamous Cell Carcinoma
NCT06364384 · ClinicalTrials.gov ↗ · Rectal Squamous Cell Carcinoma
|
Phase 2 |
Recruiting |
2024-04 |
China |
IBD Biomarker Discovery and Validation Platform
NCT07686406 · ClinicalTrials.gov ↗ · Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD)
|
Observational |
Recruiting |
2022-01 |
China |
Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial
NCT07279077 · ClinicalTrials.gov ↗ · Colon Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy
|
Phase 2 |
Recruiting |
2025-11 |
China |
|
Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy
|
Not applicable |
Recruiting |
2016-02 |
China |
S-1 and Oxaliplatin (SOX) Plus Sintilimab in the Locally Advanced Esophagogastric Junction Adenocarcinoma
NCT04989985 · ClinicalTrials.gov ↗ · Locally Advanced Gastroesophageal Junction Adenocarcinoma, Chemotherapy Effect
|
Phase 2 |
Recruiting |
2021-09 |
China |
|
Efficacy and Safety of Dual-targeted Therapy With Upadacitinib and Ustekinumab Versus Intensified Ustekinumab Therapy in Crohn's Disease
|
Phase 4 |
Recruiting |
2024-07 |
China |
Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction
NCT04840264 · ClinicalTrials.gov ↗ · Metastatic Gastric Adenocarcinoma, Metastatic Gastroesophageal Junction Adenocarcinoma, Peritoneal Carcinomatosis
|
Phase 2 |
Recruiting |
2022-01 |
China |
Mesenteric Surgical Margin for Crohn's Disease Endoscopic Recurrence
NCT06241170 · ClinicalTrials.gov ↗ · Endoscopic Recurrence Rate, After Ileocolic Crohn 's Disease Surgery
|
Not applicable |
Recruiting |
2025-07 |
China |
|
Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer
|
Phase 2 |
Not yet open |
2025-01 |
China |
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer
NCT03923335 · ClinicalTrials.gov ↗ · Colorectal Neoplasms
|
Observational |
Not yet open |
2019-04 |
China |
Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery
NCT07601256 · ClinicalTrials.gov ↗ · Sepsis, Lung Injury
|
Not applicable |
Not yet open |
2026-08 |
China |
Node-Sparing Short-Course Radiotherapy Plus First-Line Therapy and PD-1 Inhibitor in Unresectable/Metastastic pMMR/MSS Gastric Cancer (MODIFI-GC)
NCT06980389 · ClinicalTrials.gov ↗ · Immune Checkpoint Therapy, Radiotherapy, Metastatic Gastric Carcinoma
|
Phase 2 |
Not yet open |
2025-05 |
China |
Fruquintinib Combined With PD-1 Inhibitor and FOLFOX as First-Line Treatment For Advanced Gastric Cancer
NCT06871527 · ClinicalTrials.gov ↗ · Gastric (Stomach) Cancer, Gastric Adenocarcinoma, Fruquintinib
|
Phase 1/2 |
Not yet open |
2025-03 |
China |
Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy
NCT07302126 · ClinicalTrials.gov ↗ · Acute Radiation Enteritis
|
Phase 2 |
Not yet open |
2025-12 |
China |
|
Effect of Different Oxygen Concentrations Before Extubation After General Anesthesia on Hypoxemia After Extubation in Post-anesthesia Care Unit
|
Not applicable |
Not yet open |
2025-12 |
China |
Preoperative (Chemo)Radiotherapy for Locally Recurrent Rectal Cancer
NCT06617052 · ClinicalTrials.gov ↗ · Locally Recurrent Rectal Cancer, Preoperative Chemoradiotherapy
|
Observational |
Not yet open |
2024-09 |
China |
Extent of Lymph Node Dissection for Advanced Right-Sided Colon Cance
NCT06986538 · ClinicalTrials.gov ↗ · Advanced Right-sided Colon Cancer, the Extent of Lymph Node Dissection
|
Not applicable |
Not yet open |
2025-06 |
China |
NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC
NCT07765667 · ClinicalTrials.gov ↗ · Rectal Adenocarcinoma, High-Risk Cancer, MSS
|
Phase 2 |
Not yet open |
2026-09 |
China |
Improvement Effect of Dexamethasone Enema for Acute Radiation-induced Rectal Injury
NCT07548736 · ClinicalTrials.gov ↗ · Acute Radiation Enteritis
|
Phase 2 |
Not yet open |
2026-04 |
China |
|
Efficacy and Safety of CDED With Anti-TNF-α Biologics in Crohn's Disease
|
Not applicable |
Not yet open |
2026-08 |
China |
|
High-protein Oral Nutrition With HMB for Active CD Patients With Sarcopenia
|
Not applicable |
By invitation |
2024-03 |
China |
Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation
NCT07239557 · ClinicalTrials.gov ↗ · Major Abdominal Surgery, Atelectasis, Lung-protective Ventilation
|
Not applicable |
By invitation |
2025-12 |
China |
|
Endoscopic Balloon Dilatation Combined With PRP Injection in Colonic Stenosis in Crohn's Disease
|
Not applicable |
By invitation |
2024-03 |
China |
The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery
NCT05733208 · Myocardial Injury, Non-cardiac Surgery, Remote Ischemic Preconditioning
|
Not applicable |
Active, closed |
2023-05 |
China |
Safety and Efficacy of Reduced-port Laparoscopic Surgery for Patients Of Colon and Upper Rectal Cancer
NCT05953662 · ClinicalTrials.gov ↗ · Colorectal Neoplasm
|
Not applicable |
Active, closed |
2023-09 |
China |
Clinical Study on the Effect of Umbilical Cord Mesenchymal Stem Cell Exosomes on Endometrial Repair of Intrauterine Adhesions
NCT07416578 · ClinicalTrials.gov ↗ · Intrauterine Adhesions, Exosomes
|
Not applicable |
Active, closed |
2026-01 |
China |
Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers
NCT07038122 · ClinicalTrials.gov ↗ · Locally Advanced Rectal Carcinoma
|
Not applicable |
Active, closed |
2025-07 |
China |