Maze Therapeutics is the lead sponsor of 3 current clinical trials in our USA, UK, France and EU (CTIS) registers. 2 are recruiting patients now. All registered phases are Phase 2. The most-studied condition is Proteinuric Kidney Disease.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
NCT06830629 · ClinicalTrials.gov ↗ · Proteinuric Kidney Disease
|
Phase 2 | Recruiting | 2025-02 | UK, USA, France |
|
A Study of MZE782 in Adults With PKU
NCT07694440 · ClinicalTrials.gov ↗ · Phenylketonuria (PKU)
|
Phase 2 | Recruiting | 2026-06 | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Authorised or ongoing trials in the EU Clinical Trials Information System with Maze Therapeutics as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.
| Study | Phase | Status | Countries |
|---|---|---|---|
|
A Phase 2, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Safety, Tolerability, and Efficacy of MZE782 in Adults with Phenylketonuria (PKU)
2026-525622-37-01 · Nutritional and Metabolic Diseases
|
Phase 2 | Authorised | Germany, France, Netherlands |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 2 | 2 |
| Clinical trials in UK | 1 | 1 |
| Clinical trials in France | 1 | 1 |
| EU register (CTIS) | 1 | — |
A trial with sites in more than one country appears in each of those registers.
Maze Therapeutics is the lead sponsor of 2 current trials on ClinicalTrials.gov in our USA, UK and France registers, and 1 authorised or ongoing trial in the EU register (CTIS), as of the registry sync on 1 October 2026. Completed and withdrawn studies are not counted.
Yes. 2 of its 2 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 1 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.