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Priya Life Science Compound trial record
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Compound · clinical trials

Urifron clinical trials

Also listed in trial records as Recombinant Interferon Alfa-2b, Alfatronol, Bioferon, Glucoferon, IFN alpha-2B, Interferon alfa 2b, Interferon Alpha-2b, Sch 30500, Viraferon, Intron-A, IFN-α 2b
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our Canada, Mexico, Israel and Ireland registers that name Urifron as an intervention. Synced 1 Oct 2026
4Current trials
0Recruiting now
2Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov registry records · Last verified · Editorial standards
At a glance

Urifron is named as an intervention in 4 current clinical trials in our Canada, Mexico, Israel and Ireland registers. None are recruiting at the moment. All registered phases are Phase 3. The sponsor with the most trials is National Cancer Institute (NCI) (3). The most-studied condition is Clinical Stage III Cutaneous Melanoma AJCC v8.

Where Urifron is approved

All regulators →

Of the three regulators tracked here, the first to approve Urifron was the US, on 4 Jun 1986. It is approved in 2 of the 3 regulators tracked here.

USUnited States (FDA)
4 Jun 1986
Intron A
BLA103132 on Drugs@FDA
First original NDA/BLA approval
EUEuropean Union (EMA)
9 Mar 2000
IntronA
EMA product page
First centralised authorisation
CACanada (Health Canada)
No new-drug Notice of Compliance since 1994
First new-drug NOC

From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.

Trials by status

  • Active, closed4100%

Trials by phase

  • Phase 34100%
01

Clinical trials of Urifron

4 trials
StudyPhaseStatusLead sponsorRegisters
High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma
NCT00003641 · ClinicalTrials.gov ↗ · Melanoma (Skin)
Phase 3 Active, closed ECOG-ACRIN Cancer Research Group Canada
Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor
NCT00569127 · ClinicalTrials.gov ↗ · Colorectal Neuroendocrine Tumor G1, Gastric Neuroendocrine Tumor G1, Neuroendocrine Neoplasm
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery
NCT01274338 · ClinicalTrials.gov ↗ · Melanoma of Unknown Primary, Recurrent Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Mexico, Israel
Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
NCT02506153 · Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma
Phase 3 Active, closed National Cancer Institute (NCI) Ireland, Canada, Mexico, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Urifron

13 conditions
Clinical Stage III Cutaneous Melanoma AJCC v81Clinical Stage IV Cutaneous Melanoma AJCC v81Metastatic Cutaneous Melanoma1Metastatic Mucosal Melanoma1Melanoma of Unknown Primary1Recurrent Melanoma1Stage IIIB Cutaneous Melanoma AJCC v71Stage IIIC Cutaneous Melanoma AJCC v71Colorectal Neuroendocrine Tumor G11Gastric Neuroendocrine Tumor G11Neuroendocrine Neoplasm1Neuroendocrine Tumor1
All 13 conditions
Condition (as registered)Trials
Clinical Stage III Cutaneous Melanoma AJCC v81
Clinical Stage IV Cutaneous Melanoma AJCC v81
Metastatic Cutaneous Melanoma1
Metastatic Mucosal Melanoma1
Melanoma of Unknown Primary1
Recurrent Melanoma1
Stage IIIB Cutaneous Melanoma AJCC v71
Stage IIIC Cutaneous Melanoma AJCC v71
Colorectal Neuroendocrine Tumor G11
Gastric Neuroendocrine Tumor G11
Neuroendocrine Neoplasm1
Neuroendocrine Tumor1
Melanoma (Skin)1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
National Cancer Institute (NCI)3
ECOG-ACRIN Cancer Research Group1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Canada30
Clinical trials in Mexico30
Clinical trials in Israel30
Clinical trials in Ireland10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Urifron trials

How many clinical trials are testing Urifron?

4 current trials in our Canada, Mexico, Israel and Ireland registers name Urifron (also registered as Recombinant Interferon Alfa-2b) as a drug or biological intervention, as of the registry sync on 1 October 2026. Completed and withdrawn studies are not counted.

Are Urifron trials recruiting patients?

Not at the moment. None of the 4 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors Urifron clinical trials?

National Cancer Institute (NCI) (3) and ECOG-ACRIN Cancer Research Group (1). The number in brackets is how many trials each organisation leads.

Are there Urifron clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Urifron works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Urifron works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Urifron (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 1 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.