Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery

Condition(s) studied

Investigational drug(s) / intervention(s)

Standard Ventilation: Volume-controlled mechanical ventilation using standard ventilator settings during general anesthesia.

Hypoventilation: Volume-controlled mechanical ventilation using reduced tidal volume and respiratory rate during general anesthesia.

Intermittent Apnea Ventilation: Intermittent apnea periods applied during selected stages of retrograde intrarenal surgery to reduce kidney motion.

One-Lung Ventilation: One-lung ventilation applied during selected stages of retrograde intrarenal surgery to reduce kidney motion.

Study summary

This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia. The study aims to determine whether reducing respiratory-related kidney movement improves surgical success and decreases perioperative complications. Eighty adult patients will be randomly assigned to standard ventilation, hypoventilation, intermittent apnea ventilation, or one-lung ventilation. Surgical outcomes and perioperative complications will be compared between groups.

Eligibility

Primary outcome measure(s)

• Kidney Motion During Retrograde Intrarenal Surgery — During surgery
  Kidney motion during surgery will be evaluated and compared among the four ventilation strategies.

Trial sites (1)

More Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey trials in Turkey

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