Design and Validation of a Personalized Preventive System for Adolescents Based on Biological Maturity, Body Composition, and Musculoskeletal Function.

Condition(s) studied

Investigational drug(s) / intervention(s)

Personalized Preventive Physiotherapy and Exercise Program: This intervention consists of a personalized preventive physiotherapy and exercise program designed according to each participant's biological maturation status and functional assessment. The program lasts 12 weeks and includes two supervised sessions per week. Sessions focus on neuromuscular control, strength development, mobility, balance, core stability, and postural control. The intervention is individualized based on baseline and periodic reassessments, allowing progression and adjustment throughout the program. All sessions are supervised by qualified professionals.

Study summary

This study aims to evaluate the effectiveness of a personalized preventive physiotherapy and exercise program based on biological maturation status in adolescents aged 14 to 15 years. During adolescence, rapid growth and differences in biological maturation can increase the risk of musculoskeletal imbalances, pain, and injuries, especially in physically active youth. However, most preventive programs are designed according to chronological age rather than biological development.

Participants will be assessed using non-invasive methods to determine biological maturation, body composition, and musculoskeletal function, including strength, balance, mobility, and postural control. Based on these assessments, participants in the intervention group will receive a 12-week individualized preventive physiotherapy program adapted to their maturation stage, while the control group will continue with their usual school or sports activities without structured intervention.

The study will compare changes in musculoskeletal function, body composition, pain perception, and lifestyle-related variables between baseline and post-intervention assessments. The results are expected to provide evidence for a maturation-based preventive approach that can be applied in clinical, school, and sports settings to reduce injury risk and improve musculoskeletal health in adolescents.

Eligibility

Primary outcome measure(s)

• Lower-limb Strength (Isometric) — Baseline and 12 weeks
  Change in lower-limb isometric strength assessed using digital dynamometry during standardized testing procedures.
• Postural Balance — Baseline and 12 weeks
  Change in postural balance assessed using instrumented balance testing (e.g., force platform and inertial sensors) during standardized static and dynamic tasks.

Trial sites (1)

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