UBT251: UBT251 will be administered subcutaneously once-weekly.
UBT251 Placebo: UBT251 placebo will be administered subcutaneously once-weekly.
Semaglutide: Semaglutide will be administered subcutaneously once-weekly.
Semaglutide Placebo: Semaglutide placebo will be administered subcutaneously once-weekly.
The study is testing UBT251 in participants with type 2 diabetes. The purpose of this clinical study is to find out if UBT251 is effective and safe for treating participants with type 2 diabetes. Participants will either get UBT251, UBT251 placebo, semaglutide, or semaglutide placebo. Which treatment participants get is decided by chance. UBT251 is the treatment being tested and is not yet available for doctors to prescribe, while semaglutide is a medicine used to treat type 2 diabetes that doctors can already prescribe.
| Facility | City | Region | Status |
|---|---|---|---|
| Flourish Research | Birmingham | Alabama | Recruiting |
| Ark Clinical Research | Fountain Valley | California | Recruiting |
| Ark Clinical Research | Long Beach | California | Recruiting |
| Los Angeles Institute for Metabolic Research | Los Angeles | California | Recruiting |
| Catalina Research Institute, LLC | Montclair | California | Recruiting |
| Encore Medical Research LLC | Hollywood | Florida | Recruiting |
| South Broward Research LLC | Miramar | Florida | Recruiting |
| Encore Medical Research of Weston | Weston | Florida | Recruiting |
| Midwest Inst For Clin Res | Indianapolis | Indiana | Not Yet Recruiting |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | Recruiting |
| MD Medical Research | Oxon Hill | Maryland | Recruiting |
| PharmQuest | Greensboro | North Carolina | Not Yet Recruiting |
| KDCILM, LLC & Accellacare US, Inc. | Wilmington | North Carolina | Recruiting |
| Plains Clinical Research Center, LLC_Fargo | Fargo | North Dakota | Not Yet Recruiting |
| Preferred Primary Care Physicians, Inc. | Uniontown | Pennsylvania | Recruiting |
| Monroe Biomedical Research, LLC | North Charleston | South Carolina | Recruiting |
| LifeDoc Health | Memphis | Tennessee | Recruiting |
| IMA Clinical Research | Austin | Texas | Recruiting |
| Private Practice - Dr. Laila A. Hassan | Houston | Texas | Recruiting |
| Radiance Clinical Research | Lampasas | Texas | Recruiting |
| Quality Research Inc | San Antonio | Texas | Recruiting |
| Tekton Research Inc | San Antonio | Texas | Recruiting |
| Consano Clin Res-Shavano Park | Shavano Park | Texas | Recruiting |
| Chrysalis Clinical Research | St. George | Utah | Recruiting |
| The Vancouver Clinic | Vancouver | Washington | Not Yet Recruiting |
| Castle Hill Medical Centre | Castle Hill | New South Wales | Recruiting |
| Novatrials | Charlestown | New South Wales | Not Yet Recruiting |
| Hunter Medical Research Institute - Endocrinology and Diabetes | New Lambton Heights | New South Wales | Not Yet Recruiting |
| Roger Chih Yu Chen | Sydney | New South Wales | Recruiting |
| Royal Adelaide Hospital - Cardiology Department | Adelaide | South Australia | Recruiting |
| Baker Heart and Diabetes Institute | Melbourne | Victoria | Recruiting |
| Versdias - Diabetologikum Amberg | Amberg | Bavaria | Recruiting |
| Herz- und Diabeteszentrum NRW - Bad Oeynhausen | Bad Oeynhausen | Germany | Recruiting |
| Medizinisches Versorgungszentrum Am Bahnhof Spandau GbR | Berlin | Germany | Recruiting |
| DSP Bochum, Diabetes- und Stoffwechselpraxis | Bochum | Germany | Not Yet Recruiting |
| Studiengesellschaft Dres. Könemann/Steinmann GbR | Bünde | Germany | Not Yet Recruiting |
| InnoDiab Forschung GmbH | Essen | Germany | Recruiting |
| Mesut Durmaz, Hof | Hof | Germany | Recruiting |
| CRS Clinical Research Services Mannheim GmbH (hVIVO Mannheim) | Mannheim | Germany | Recruiting |
| Szegedi Tudomanyegyetem St Györgyi Albert Klinikai Központ | Szeged | Csongrád-Csanád | Recruiting |
+ 30 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07668388 on ClinicalTrials.gov ↗ ← All trials in Germany