Standardized military march: 6 km march carrying 15 kg of equipment. The march will be conducted in uniform in accordance with central military regulations. Participants will be equipped with a continuous glucose monitor an electrocardiography wearable during the march.
Before and after the march blood and urine samples will be obtained.
Study summary
As part of the mandatory annual assessment of physical fitness, soldiers are required to complete a standardized military march. A total of 100 healthy volunteer participants will be recruited from soldiers serving at the Bundeswehr Hospital Ulm. During this march, physiological and metabolic parameters will be assessed.
At baseline, anthropometric data and information on medical history, lifestyle, and fitness status will be collected, including a validated questionnaire on physical activity. Blood and urine samples will be obtained to determine routine laboratory and metabolic parameters, and body composition will be assessed using bioelectrical impedance analysis. In addition, selected sensors will be applied to continuously record physiological data.
Participants will then complete a 6 km march carrying 15 kg of equipment. After completion of the march, sensors will be removed and additional blood and urine samples will be collected to evaluate metabolic responses to physical exertion, including catecholamine levels.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* BMI between 18.5 and 30 kg/m\^2
Exclusion Criteria:
* Pregnancy or lactation
* cardiovascular disease
* vegan diet
* drug or alcohol abuse
* Drug therapy that raises or lowers blood sugar, e.g. steroids, antidiabetics, insulin or influences the autonomic nervous system
* No consent to be informed about incidentally discovered pathological findings
* Any other (clinical) condition that would endanger participants safety or question scientific success according to the physicians opinion.
Primary outcome measure(s)
Glucose dynamics during exercise — 1 hour Interstitial glucose responses during the standardized endurance exercise (6 kilometer march with 15 kilogram load) measured via continuous glucose monitoring.
Sympathetic nervous system activation (catecholamines) — Baseline, immediately after the march (approximately 1 hour after baseline) Activation of the sympathetic nervous system during a standardized endurance exercise measured via changes in catecholamine levels.
Correlation between sympathetic activation (catecholamines) and glucose dynamics during endurance exercise — Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline) Correlation between sympathetic nervous system activation measured via catecholamine levels and glucose responses during a standardized endurance exercise (6 kilometer march with 15 kilogram load).
Heart rate variability — Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline) Heat rate variability during a standardized endurance exercise measured via electrocardiography.
Correlation between heart rate variability and glucose dynamics during endurance exercise — Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline) Correlation between heart rate variability and glucose responses during a standardized endurance exercise (6 kilometer march with 15 kilogram load).
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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