EEG Measurements to Capture DBS-induced Electric Potentials

NCT07115394 · tracked via the Priya Life Science Germany tracker

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Phase

Observational

Started

2025-07-11

Last updated

2025-08-21

Condition(s) studied

Deep Brain StimulationParkinson's Disease

Investigational drug(s) / intervention(s)

EEG recording

EEG recording: EEG will be recorded at high sampling rate

Study summary

To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (\>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (\>100 kHz).

Eligibility

Sex

ALL

Min age

35 Years

Max age

85 Years

Healthy volunteers

Inclusion Criteria: * Provision of written informed consent by the patient * Age 35 - 85 * patient groups: Parkinson's disease, essential tremor, dystonia * \>3 months after surgery for DBS Exclusion Criteria: none.

Primary outcome measure(s)

Electric potential at the EEG locations — during DBS
The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data.

Trial sites (1)

Facility	City	Region	Status
University Medical Center Hamburg-Eppendorf	Hamburg	Germany	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07115394 on ClinicalTrials.gov ↗ ← All trials in Germany