External Validation of the MASCAN Score for the Classification of Difficult Mask Ventilation

NCT07114549 · tracked via the Priya Life Science Germany tracker

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Phase

Observational

Started

2025-08-08

Last updated

2025-08-21

Condition(s) studied

Airway ManagementGeneral AnesthesiaMask Ventilation

Study summary

The MASCAN Score is a prospectively developed objective classification for difficult facemask ventilation. This prospective observational study aims to externally validate the MASCAN score in patients undergoing general anaesthesia for surgical procedures and to determine the influence of different approaches and techniques, such as the timing of neuromuscular blocking agents and manual versus controlled facemask ventilation. A secondary aim is to determine the diagnostic value of visual assessments of the capnography curve. Another secondary aim of the study is to compare the assessment of the first attempt success during tracheal intubation between the airway operator and an independent observer.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patients who are scheduled for surgery with general anesthesia and require facemask ventilation and tracheal intubation after induction of anesthesia * Patients aged 18 years or older * Provided informed consent Exclusion Criteria: * Pregnant or breastfeeding woman * Required rapid sequence induction or other contraindications for facemask ventilation * Planned awake tracheal intubation * No consent given

Primary outcome measure(s)

Difficult facemask ventilation — 1 hour
Alert documented in patients health records by the airway operator following facemask ventilation

Trial sites (1)

Facility	City	Region	Status
University Medical Center Hamburg-Eppendorf	Hamburg	Free and Hanseatic City of Hamburg	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07114549 on ClinicalTrials.gov ↗ ← All trials in Germany