" The French Gut " is a national contribution aiming to collect 100,000 faecal samples and associated nutritional and clinical data by 2027. Le French Gut is initiated by MetaGenoPolis-INRAE, supported by INRAE with Prof. R. Benamouzig, (AP-HP) as principal investigator of the project. The main goal of this national trial is a better understanding of the observed heterogeneity between gut microbiome of healthy subjects, its connections with the diet and lifestyle, but also changes in gut microbiota associated with diseases (diabetes, obesity, allergies, cancer, Parkinson, Alzheimer…).
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Persons over the age of 18 living in France.
* Consent form signed electronically.
Non inclusion Criteria:
* Non-adult person (declarative);
* Person not living in France (declarative);
* Persons subject to a protective measure, in particular under guardianship or curatorship or unable to express their consent (declarative);
* Person having had a colectomy (declarative);
* Person with a digestive stoma (declarative);
* Person who has not signed the consent;
* Person who did not answer the entry questionnaire;
* Person who has not sent a compliant stool sample;
* Antibiotic intake in the 3 months before inclusion (declarative);
* Performing a colonoscopy in the 3 months preceding inclusion (declarative).
Primary outcome measure(s)
Characterize the heterogeneity and diversity of the gut microbiota of subjects living in France — 5 up to 15 years The gut microbiota of participants will be characterized by describing the presence and abundance in the samples of each gut microbial genes listed in our up-to-date gene catalogue. From these data, the presence and abundance of the different taxonomic ranks will be deduced, ranging from a fine granularity at species and strain level to a more 'zoomed out' phylum level. The richness and diversity of the microbiome (genes and species) will be described. The functional modules, corresponding to the metabolic pathways encoded by the species detected in each sample, will be determined.
Trial sites (1)
Facility
City
Region
Status
Centre de Recherche sur Volontaire
Bobigny
France
Recruiting
More Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement trials in France
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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