The aim of this research is to assess the relationship between metabolic syndrome and gastroesophageal reflux disease (GERD). seeking to determine how components of metabolic syndrome contribute to the risk and severity of GERD.
Eligibility
Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
\- 2.3.1-Type of the study: This study will be designed as an observational, cross-sectional, analytical study.
2.3.2-StudySetting: This study will be performed at internal medicine, Assuit University Hospitals
2.3.3-Studysubjects:
1. Inclusion Criteria:
* Adult patients aged 18 years and above.
* Patients diagnosed with metabolic syndrome based on standard criteria (e.g., NCEP ATP III).
* Patients who will undergo upper gastrointestinal (GI) evaluation for GERD symptoms.
2. Exclusion Criteria:
1. Patients with a history of upper GI surgery.
2. Pregnant or lactating women.
3. Patients with known malignancy or severe comorbid illness.
4. Patients currently taking proton pump inhibitors (PPIs) or other acid-suppressive therapy.
5. Unwilling or unable to provide informed consent.
Exclusion Criteria:
\-
Primary outcome measure(s)
the prevalence and severity of GERD among patients with metabolic syndrome, as determined by endoscopic assesment — 1 year .endoscopic findings los angles criteria Grade A : one or more mucosal breaks not more than 5mm Grade b: one or more mucosal breaks more than 5mm Grade c : one or more mucosal breaks extending between tops of two mucosal folds but involving less than 75% of esophageal circumference Grade D : one or more mucosal breaks involving 75% of oesophageal circumference
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.