Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
SubcostalLateralTransversus Abdominis Plane BlockPostoperative AnalgesiaThoracic Epidural AnalgesiaMajor Abdominal Cancer Surgery
Investigational drug(s) / intervention(s)
Subcostal and lateral transversus abdominis plane blockThoracic epidural anesthesia
Subcostal and lateral transversus abdominis plane block: Patients will receive an ultrasound-guided combined subcostal and lateral transversus abdominis plane block.
Thoracic epidural anesthesia: Patients will receive an ultrasound-guided thoracic epidural anesthesia.
Study summary
This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I-III.
* Scheduled for major abdominal surgeries including: (e.g., gastrectomy, colectomy, hepatectomy, cystectomy, total abdominal hysterectomy, Nephrectomy, pancreatectomy).
Exclusion Criteria:
* Intraoperative hemodynamic instability.
* History or evidence of coagulopathy.
* Infection or abdominal wall masses at injection site.
* Morbid obesity.
* Other Medical conditions including mental illness or substance abuse.
* Known allergy to local anesthetics.
* Chronic opioid use or chronic pain conditions.
* Pregnancy.
Primary outcome measure(s)
Total morphine consumption — 24 hours postoperatively Rescue analgesia of morphine will be given as 3 mg bolus if the Visual Analogue Scale (VAS) \> 3 to be repeated after 30 min if pain persists until the VAS \< 4.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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