Mechanical Ventilation Pressure HighBariatric Surgery Candidate
Investigational drug(s) / intervention(s)
titated PEEP to best static compliance
titated PEEP to best static compliance: the Intraoperative PEEP will be titrated to best static compliance for each patient
Study summary
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics.
In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications
Eligibility
Sex
ALL
Min age
16 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Patients were eligible for participation if the met the following criteria
* Age between 18 and 60 years old.
* Body mass index \> 40
* Laparoscopic bariatric elective surgery under general anesthesia.
* ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.
Exclusion Criteria:
* Previous lung surgery
* ASA status III or IV.
* Moderate to severe obstructive or restrictive lung disease .
* Persistant intraoperative hemodynamic instability .
* Need for postoperative mechanical ventilation
Primary outcome measure(s)
postoperative pulmonary complication — postoperative 10 days after surgery pneumonia-atelactasis-bronchospasm-respiratory failure
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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