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Clinical trial register · China

Clinical Trials in Guangzhou

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 19052 matching records held by the registry are in this view. Synced 22 Sep 2026, 11:10 UTC
19052
Studies in scope
all four open statuses
11786
Recruiting now
open to new participants
2009
Lead sponsors
across recruiting studies
Top sites
Guangzhou 81 Foshan 4 Shantou 3 Guanzhou 3 Shenzhen 3
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Guangzhou81 Foshan4 Shantou3 Guanzhou3 Shenzhen3
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81 of 19052 studies
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Study
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Phase
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Chinese sites
Start
Not yet open
Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial
NCT07686796Local Advanced Rectal Cancer, PD-1 Inhibitor, PCSK9 Inhibitor, RCT
Guangdong Provincial People's Hospital
Phase 3
148
Guangzhou
2027-01-01
Not yet open
Terbinafine for CSA-AKI Prevention
NCT07738328Acute Kidney Injury, Cardiac Surgical Procedures
Guangdong Provincial People's Hospital
Phase 2
208
Guangzhou
2026-09-01
Not yet open
Microbiota in Neoadjuvant Chemoimmunotherapy for NSCLC
NCT07752589Non-Small Cell Carcinoma of Lung, Gut Microbiomes, Neoadjuvant Chemoimmunotherapy
Guangdong Provincial People's Hospital
Observational
100
Guangzhou
2026-07-31
Recruiting
Bevacizumab, Sintilimab, Cetuximab and Irinotecan in Refractory RAS Wild-type Metastatic Colorectal Cancer: BOND-4 Trial
NCT07722754Colorectal Neoplasms Malignant, Neoplasm, Metastatic
Guangdong Provincial People's Hospital
Phase 2
160
Guangzhou
2026-07-23
Not yet open
Multicenter Prospective Validation of AI Models for Malignancy Risk Prediction in Pulmonary Nodules
NCT07727122Pulmonary Nodules
Guangdong Provincial People's Hospital
Observational
3,000
Chongqing, Guangzhou, Xuzhou, Hangzhou
2026-07
Not yet open
Short-Course Radiotherapy, Nal-IRI, Capecitabine, and Camrelizumab for Locally Advanced MSS Rectal Cancer
NCT07521605Rectal Cancer Patients
Guangdong Provincial People's Hospital
Phase 2
44
Guangzhou
2026-05-20
Recruiting
Weight Loss Via Intelligent Guidance in Patients With Coronary Heart Disease and Obesity: a Randomized Clinical Trial
NCT07514611CHD, Overweight or Obese
Guangdong Provincial People's Hospital
Not applicable
140
Guangzhou
2026-04-18
Recruiting
A Novel Intraoperative Fluorescence-guided System for Evaluating Margins During Breast-conserving Surgery for Breast Cancer
NCT07352930Breast-Conserving Surgery
Guangdong Provincial People's Hospital
Not applicable
172
Guangzhou
2026-04-01
Recruiting
Catheter Ablation Plus LAAO Versus Anticoagulation in Frail Elderly Patients With Atrial Fibrillation
NCT07441382Atrial Fibrillation (AF), Stroke, Hemorrhage, Frailty
Guangdong Provincial People's Hospital
Not applicable
200
Guangzhou
2026-03-24
Active, closed
EFficacy and safEty of cRisugabalin on nocipLastic paIn in Patients With Parkinson's Disease (RELIEF-PD): a Multicentre, Double-blind, Randomised Controlled Trial
NCT07483398PARKINSON DISEASE (Disorder)
Guangdong Provincial People's Hospital
Phase 4
166
Guangzhou
2026-03-13
Recruiting
Multimodal Deep Learning Model for Multi-task Diagnosis and Triage Suggestions of Ophthalmic Diseases
NCT07447973Anterior Segment Diseases
Guangdong Provincial People's Hospital
Observational
2,000
Guangzhou
2026-03-10
Not yet open
Efficacy and Safety of Hyperbaric Oxygen Therapy in Improving Nab-paclitaxel-Induced Peripheral Neuropathy
NCT07410169Breast Cancer, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Paclitaxel-induced Peripheral Neuropathy
Guangdong Provincial People's Hospital
Phase 2/3
160
Guangzhou
2026-01-31
Recruiting
Yiyuancong for the Treatment of Sudden Sensorineural Hearing Loss
NCT07505667Sudden Hearing Loss, Sensorineural Hearing Loss
Guangdong Provincial People's Hospital
Not applicable
128
Guangzhou, Shenzhen, Zhongshan, Liuzhou, Ganzhou
2025-11-15
Recruiting
Scientific Validity Assessment and Optimization of AI-Generated A3/A4 Type Questions for the Chinese Medical Licensing Examination
NCT07505862AI (Artificial Intelligence)
Guangdong Provincial People's Hospital
Observational
20
Guangzhou
2025-10-01
Recruiting
A Study of Pegmolesatide of in Dialysis Chronic Kidney Disease (CKD) Patients With Anemia Treated With Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitor (HIF-PHI)
NCT07136792Renal Anemia of Chronic Kidney Disease
Guangdong Provincial People's Hospital
Not applicable
96
Beijing, Longyan, Zhangzhou, Guangzhou, Meizhou, Shantou, Shaoguan, Zhongshan
2025-09-08
Recruiting
Efficacy and Safety of Nalfurafine Hydrochloride ODT for Moderate-to-Severe Pruritus in Patients on Peritoneal Dialysis
NCT07098351Adverse Event, Peritoneal Dialysis, Moderate-to-severe Pruritus, Chronic Kidney Disease-associated Itch
Guangdong Provincial People's Hospital
Not applicable
93
Guangzhou
2025-08-07
Active, closed
Acute Myocardial Infarction Prediction Using Artificial Intelligence Applied to Electrocardiogram Images
NCT07163767Acute Myocardial Infarction (AMI), Electrocardiography, Artifical Intelligence
Guangdong Provincial People's Hospital
Observational
150,000
Guangzhou
2025-08-01
Not yet open
Fasting-Mimicking Diet as an Adjunct to Neoadjuvant Chemotherapy for Hormone-Receptor-Positive Breast Cancer
NCT07077018Fasting-Mimicking Diet, Breast Cancer, Neoadjuvant Chemotherapy
Guangdong Provincial People's Hospital
Not applicable
45
Guangzhou
2025-07-12
Recruiting
A Study of Real-world Events of Vericiguat in Patients With Chronic Kidney Disease and Heart Failure
NCT07047547Hemodialysis Complication, Heart Failure
Guangdong Provincial People's Hospital
Not applicable
118
Guangzhou
2025-06-01
Not yet open
Investigation Into the Safety and Efficacy of ICG-Labeled Fluorescence Imaging Technology in Guiding the Resection of Bone and Soft Tissue Tumors
NCT06979115Bone Neoplasms, Soft Tissue Neoplasms
Guangdong Provincial People's Hospital
Observational
40
Guangzhou
2025-05-25
Not yet open
Magnesium-L-Threonate Improves Menopausal Symptoms
NCT06959745Menopause Syndrome, Magnesium
Guangdong Provincial People's Hospital
Not applicable
50
Guangzhou
2025-05-15
Recruiting
Safety and Efficacy of Exercise in Type-B Aortic Dissection
NCT07009067Type B Aortic Dissection
Guangdong Provincial People's Hospital
Not applicable
20
Guangzhou
2025-05-06
Recruiting
Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study)
NCT07025590Cardiovascular Diseases (CVD), Depression Anxiety Disorder
Guangdong Provincial People's Hospital
Not applicable
106
Guangzhou
2025-04-22
Active, closed
PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer
NCT06933251Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital
Phase 2
30
Guangzhou
2025-04-20
Recruiting
A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Resectable Pancreatic Cancer
NCT06758544Pancreatic Cancer
Guangdong Provincial People's Hospital
Phase 1/2
18
Guangzhou
2025-03-17
Not yet open
Guideline-diRected MAnagement for Chronic Kidney Disease: EValuation of an Education Progamme in a National Cluster Randomized Controlled Trial
NCT06825676Renal Insufficiency, Chronic, Cardiovascular Diseases (CVD)
Guangdong Provincial People's Hospital
Not applicable
1,800
Guangzhou
2025-03
Recruiting
NK010 or NK042 in Combination With Rituximab for Refractory Systemic Lupus Erythematosus/Lupus Nephritis
NCT06676631Refractory Systemic Lupus Erythematosus, Refractory Lupus Nephritis
Guangdong Provincial People's Hospital
Phase 1
18
Guangzhou
2025-02-19
Not yet open
A Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Hormone Receptor Positive Breast Cancer Patients
NCT06825949Breast Cancers
Guangdong Provincial People's Hospital
Not applicable
55
Guangzhou
2025-02-15
Not yet open
A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Triple-Negative and HER2+ Breast Cancer Patients
NCT06825975Breast Cancers
Guangdong Provincial People's Hospital
Not applicable
348
Guangzhou
2025-02-12
Not yet open
Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs
NCT06819501Breast Cancers
Guangdong Provincial People's Hospital
Not applicable
226
Guangzhou
2025-02-05
Recruiting
A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Breast Cancer Patients
NCT06811870Breast Cancers
Guangdong Provincial People's Hospital
Phase 1/2
161
Guangzhou, Shantou
2025-02-01
Recruiting
Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC
NCT06771960Lung Cancer (NSCLC)
Guangdong Provincial People's Hospital
Observational
120
Guangzhou
2025-02-01
By invitation
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
NCT07130968MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
Guangdong Provincial People's Hospital
Observational
200,000
Guangzhou
2025-02-01
Not yet open
This Study Aims to Explore the Efficacy of Hyperbaric Oxygen in the Treatment of Flap Ischaemic Necrosis After Breast Cancer Surgery
NCT06811857Flap Necrosis, Flap Ischemia
Guangdong Provincial People's Hospital
Not applicable
76
Guangzhou
2025-01-31
Recruiting
Community Exercise Treating Effect on Cardiopulmonary Disease Patients
NCT07154355Coronary Heart Disease (CHD), Heart Failure, Cardiomyopathy, COPD
Guangdong Provincial People's Hospital
Not applicable
200
Guangzhou
2025-01-30
Active, closed
A Randomized Controlled Study of Serplulimab Combined With Chemotherapy for Locally Advanced Gastric Adenocarcinoma
NCT07257575Gastric Cancer Stage III
Guangdong Provincial People's Hospital
Phase 2
138
Guangzhou
2025-01-05
Not yet open
MRNA Neoantigen Vaccine in Non-Small Cell Lung Cancer
NCT06735508NSCLC
Guangdong Provincial People's Hospital
Phase EARLY_PHASE1
40
Guangzhou
2025-01
Recruiting
D-BACE in Combination With Chemotherapy and Carelizumab for Resectable II-IIIA or Potentially Resectable T3-4N2 Stage IIIB NSCLC
NCT07016126NSCLC (Non-small Cell Lung Cancer)
Guangdong Provincial People's Hospital
Phase 3
70
Guangzhou
2024-12-22
Recruiting
The Safety and Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Metastatic Adenocarcinoma
NCT06743867Peritoneal Carcinoma Metastatic
Guangdong Provincial People's Hospital
Phase 1
30
Guangzhou
2024-12-11
Not yet open
A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary Nodules
NCT06458673Solitary Lung Nodule, Multiple Pulmonary Nodules
Guangdong Provincial People's Hospital
Observational
1,184
Guangzhou
2024-12-01
Recruiting
Safety and Effectiveness of Early Aspirin Administration After Mitral Valve Repair
NCT06738992Mitral Valve Repair Surgery
Guangdong Provincial People's Hospital
Phase 4
384
Guangzhou
2024-11-14
Recruiting
Organoid-based Functional Precision Therapy for Advanced Breast Cancer
NCT06102824HER2-negative Breast Cancer, Advanced Breast Cancer
Guangdong Provincial People's Hospital
Phase 2
252
Guangzhou
2024-10-01
Active, closed
A Prospective Observational Study of Changes in Cortisol Levels After Neoadjuvant Immunotherapy and Their Prognostic Value in Patients With NSCLC
NCT07530276NSCLC
Guangdong Provincial People's Hospital
Observational
330
Guangzhou
2024-08-30
Not yet open
Safety and Efficacy of Degradable Magnesium Metal Clips in Surgical Margins of Radical Surgery for Malignant Bone and Soft Tissue Tumors
NCT06550765Sarcoma, Soft Tissue, Sarcoma, Spindle Cell
Guangdong Provincial People's Hospital
Not applicable
98
Guangzhou
2024-08-25
Recruiting
Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML
NCT06451861Acute Myeloid Leukemia
Guangdong Provincial People's Hospital
Phase 2
240
Dongguan, Foshan, Guangzhou, Shenzhen, Zhanjiang, Zhuhai, Haikou
2024-08-21
Recruiting
Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue Sarcoma
NCT06506838Soft Tissue Sarcoma, Doxorubicin, Radiotherapy
Guangdong Provincial People's Hospital
Phase 4
39
Guangzhou
2024-08-10
By invitation
The Effects and Neural Mechanisms of Vitamin D and Iron-Immune Homeostasis on Inhibitory Control in Obsessive-Compulsive Disorder
NCT07763977Obsessive Compulsive Disorder (OCD)
Guangdong Provincial People's Hospital
Not applicable
60
Guangzhou
2024-08-06
Recruiting
PARPi or Capecitabine Combined With PD-1 Inhibitors as Adjuvant Therapy in High-risk TNBC
NCT06533384Triple-negative Breast Cancer
Guangdong Provincial People's Hospital
Phase 3
310
Guangzhou
2024-08-01
Active, closed
Brolucizumab Efficacy and Safety Single-Arm Descriptive Trial in Patients With Persistent Diabetic Macular Edema
NCT06498050Diabetic Macular Edema
Guangdong Provincial People's Hospital
Phase 4
52
Guangzhou
2024-07-10
Recruiting
Neoadjuvant Envafolimab Plus Disitamab Vedotin and Carboplatin in Resectable HER2-Mutant Non-Small-Cell Lung Cancer
NCT06734182Non-small Cell Lung Cancer
Guangdong Provincial People's Hospital
Phase 2
25
Guangzhou
2024-06-22
Recruiting
Study of Serplulimab Plus Chemotherapy as Neoadjuvant Therapy for Limited-stage Small Cell Lung Cancer (LS-SCLC)
NCT06911606SCLC, Limited Stage
Guangdong Provincial People's Hospital
Phase 2
45
Guangzhou
2024-05-22
Not yet open
Transfusion in Cardiac Valve Surgery
NCT06332547Cardiac Surgery With Cardiopulmonary Bypass, Valve Heart Disease
Guangdong Provincial People's Hospital
Not applicable
1,600
Guangzhou
2024-04-01
Active, closed
Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC
NCT06300424Non Small Cell Lung Cancer, EGFR Gene Mutation
Guangdong Provincial People's Hospital
Phase 2
32
Guangzhou
2024-04-01
Recruiting
The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis
NCT06244264Spinal Metastases, Blood Transfusion Complication, Lung Cancer, Surgery
Guangdong Provincial People's Hospital
Not applicable
118
Guangzhou
2024-03-15
Recruiting
Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients
NCT06215326Lung Cancer
Guangdong Provincial People's Hospital
Not applicable
100
Guangzhou
2024-01-23
Recruiting
EACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHF
NCT06161987Acute Decompensated Heart Failure
Guangdong Provincial People's Hospital
Not applicable
140
Guangzhou
2023-12-01
Recruiting
A Study of Chidamide With AZA in MRD Positive AML After Transplant
NCT06066905AML, Adult, Minimal Residual Disease
Guangdong Provincial People's Hospital
Not applicable
60
Guangzhou
2023-10-26
Recruiting
Efficacy and Safety of Qishen Yiqi Dropping Pills in Patients With Severe Pulmonary Hypertension
NCT07604805Idiopathic Pulmonary Hypertension
Guangdong Provincial People's Hospital
Not applicable
120
Guangzhou
2023-10-25
Active, closed
Preoperative Evaluation of 3D Reconstruction Tool for Nipple-sparing Mastectomy
NCT06071234Breast Cancer
Guangdong Provincial People's Hospital
Not applicable
126
Guangzhou
2023-10-08
Recruiting
Lenvatinib, Tislelizumab Combined With RALOX Regimen HAIC in Advanced Hepatocellular Carcinoma
NCT05954897Hepatocellular Carcinoma
Guangdong Provincial People's Hospital
Phase 2
29
Guangzhou
2023-09-01
Recruiting
Correlation of Timing of Pegfilgrastim Administration and PIBP.
NCT05841186Pegfilgrastim, Bone Pain, Chemotherapy, Breast Cancer
Guangdong Provincial People's Hospital
Not applicable
156
Guangzhou
2023-05-04
Active, closed
Induction Lorlatinib in Stage III Non-small Cell Lung Cancer
NCT05740943Stage III NSCLC, Surgery
Guangdong Provincial People's Hospital
Phase 2
48
Beijin, Guangzhou, Changsha
2023-03-15
Active, closed
Efficacy of Triple-Combination Therapy in Severe PAH-CHD
NCT06196801Congenital Heart Disease, Pulmonary Arterial Hypertension
Guangdong Provincial People's Hospital
Observational
80
Guangzhou
2022-06-17
Recruiting
Hyperbaric Oxygen in the Prevention of Radiation Pneumonitis
NCT05189496Radiation Pneumonitis
Guangdong Provincial People's Hospital
Not applicable
380
Guangzhou
2022-03-01
Recruiting
Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC
NCT05272696Head and Neck Squamous Cell Carcinoma
Guangdong Provincial People's Hospital
Phase 2
86
Guangzhou
2022-03-01
Recruiting
Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection
NCT06404164Pulmonary Function Assessment, Disease Free Survival, NSCLC, Stage I
Guangdong Provincial People's Hospital
Not applicable
3,000
Guangzhou
2022-01-30
Recruiting
A Real World, Multi-centric, Observational Registry Study of Chronic Kidney Diseases
NCT05188885Chronic Kidney Disease
Guangdong Provincial People's Hospital
Observational
90,000
Foshan, Guangzhou, Meizhou, Qingyuan, Zhuhai, Ganzhou
2021-12-27
Recruiting
Correlation Between the Changes of Retinal Structure and Function and Ischemic Stroke
NCT05281887Ischemic Stroke
Guangdong Provincial People's Hospital
Observational
120
Guangzhou
2021-12-01
Recruiting
MRD Monitoring in Lung Cancer After Resection
NCT04976296Lung Cancer
Guangdong Provincial People's Hospital
Observational
300
Guangzhou
2021-09-01
Active, closed
Effectivity and Safety of PFO Closure vs Medicine in Alleviating Migraine
NCT04946734PFO - Patent Foramen Ovale, Migraine
Guangdong Provincial People's Hospital
Phase 3
440
Xiamen, Guangzhou, Huizhou, Jiangmen, Shenzhen, Zhanjiang, Nanning, Shangqiu
2021-08-12
Recruiting
Thrombus Aspiration in STEMI Patients With High Thrombus Burden
NCT04212494ST-segment Elevation Myocardial Infarction (STEMI)
Guangdong Provincial People's Hospital
Not applicable
3,838
Fuzhou, Foshan, Guangzhou, Huizhou, Jiangmen, Kaiping, Maoming, Shantou
2020-08-30
Active, closed
ASPIrin in Reducing Events in Dialysis ( ASPIRED )
NCT04381143CKD (Chronic Kidney Disease) Stage 5D
Guangdong Provincial People's Hospital
Phase 4
9,082
Fuzhou, Longyan, Lanzhou, Dongguan, Foshan, Guangzhou, Guanzhou, Heyuan
2020-07-30
Recruiting
Correlation of Microbiome and Metabonomics With IgA Nephropathy
NCT05190848IgA Nephropathy
Guangdong Provincial People's Hospital
Observational
600
Guangzhou, Guanzhou
2020-05-01
Active, closed
Efficacy and Safety of HMAs Combined With Venetoclax Versus HMAs Alone in ND Int-and H-risk MDS or CMML
NCT07318662MDS, CMML
Guangdong Provincial People's Hospital
Observational
224
Guangzhou
2020-01-01
Recruiting
A Cohort Study on Biomarkers of Hypertension in Guangdong Province(GDP Study)
NCT04212455Hypertension, Cardiovascular Diseases
Guangdong Provincial People's Hospital
Observational
50,000
Guangzhou
2020-01-01
Recruiting
Home Blood Pressure Monitoring Registration Study in the Elderly(HOME Study)
NCT04212468Blood Pressure
Guangdong Provincial People's Hospital
Observational
6,000
Guangzhou
2020-01-01
Recruiting
Predictive Value of Non-fasting Blood Lipid Levels for Cardiovascular Events in Community Population(PICC Study)
NCT04212520Lipid
Guangdong Provincial People's Hospital
Observational
6,500
Guangzhou
2020-01-01
Recruiting
International Big Data Centre in Emergency Medicine
NCT05616416Emergency Medicine
Guangdong Provincial People's Hospital
Observational
500,000
Guangzhou
2011-01-01
Recruiting
Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes
NCT07495774Pulmonary Hypertension
Guangdong Provincial People's Hospital
Observational
450
Guangzhou
2006-01-04
Recruiting
Association of Inpatient Blood Pressure Levels With In-hospital Adverse Events(APPLE Study)
NCT04226612Blood Pressure
Guangdong Provincial People's Hospital
Observational
100,000
Guangzhou
2000-01-01
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Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-china/city/guangzhou

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