moderate-intensity continuous traininghigh-intensity interval training
moderate-intensity continuous training: Each MICT session consists of 30 minutes of cycling. Workload will be gradually titrated from 50% to 60% peak WR throughout training to sustain a target RPE of 12-14 on the Borg 6-20 scale.
high-intensity interval training: Each HIIT session consists of15 cycles, includes a 60-second high-intensity interval at 80-95% peak WR (target RPE 15-17) followed by a 60-second active recovery phase at 25% peak WR.
Study summary
The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients scheduled for lung resections.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
1. Age\>18 years.
2. Suspected or confirmed primary lung cancer with scheduled surgical treatment.
3. Moderate-to-high perioperative risk, defined as FEV1\<60% of predicted value (wedge) or ppo FEV1\<60% of predicted value (lobectomy/segmentectomy) or VO2peak\<20 ml/kg/ min.
4. Sign informed consent and accept to comply with the requirements of the study protocol.
5. Completion of a baseline Complete cardiopulmonary exercise testing (CPET).
Exclusion Criteria:
1. Concurrent or previous history of other malignant tumors.
2. Life expectancy less than 1 year.
3. Dementia; infirmity; or inability to participate in sports (musculoskeletal limitations, namely, injuries, frailty, and weakness).
4. Inability to maintain exercise training.
5. Irregular vital signs (heart rate: \< 40 or \> 120 bpm at rest; blood pressure: systolic blood pressure \> 200 mm Hg or diastolic pressure \> 110 mm Hg; T: ≥ 38.5 or ≤ 36◦C; SpO2 ≤ 90%).
6. Currently enrolling in any other clinical trials.
7. Patient refusal.
Primary outcome measure(s)
cardiopulmonary fitness — baseline，2 weeks The post-training change in cardiorespiratory fitness will be measured by the VO2peak in ml/kg/min.VO2peak will be evaluated by a cardiopulmonary exercise test.
Trial sites (1)
Facility
City
Region
Status
Guangdong Provincial People's Hospital
Guangzhou
Guangdong
Recruiting
More Guangdong Provincial People's Hospital trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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